PT2619576T - Meios e métodos para a previsão de resposta ao tratamento de um paciente com cancro - Google Patents
Meios e métodos para a previsão de resposta ao tratamento de um paciente com cancroInfo
- Publication number
- PT2619576T PT2619576T PT117733816T PT11773381T PT2619576T PT 2619576 T PT2619576 T PT 2619576T PT 117733816 T PT117733816 T PT 117733816T PT 11773381 T PT11773381 T PT 11773381T PT 2619576 T PT2619576 T PT 2619576T
- Authority
- PT
- Portugal
- Prior art keywords
- prediction
- methods
- cancer patient
- treatment response
- response
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/7051—T-cell receptor (TcR)-CD3 complex
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70517—CD8
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96436—Granzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Compression Of Band Width Or Redundancy In Fax (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10010537 | 2010-09-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2619576T true PT2619576T (pt) | 2020-09-14 |
Family
ID=44862915
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT117733816T PT2619576T (pt) | 2010-09-24 | 2011-09-20 | Meios e métodos para a previsão de resposta ao tratamento de um paciente com cancro |
Country Status (10)
Country | Link |
---|---|
US (1) | US9726676B2 (pt) |
EP (1) | EP2619576B1 (pt) |
DK (1) | DK2619576T3 (pt) |
ES (1) | ES2816625T3 (pt) |
HR (1) | HRP20201424T1 (pt) |
HU (1) | HUE051674T2 (pt) |
PL (1) | PL2619576T3 (pt) |
PT (1) | PT2619576T (pt) |
SI (1) | SI2619576T1 (pt) |
WO (1) | WO2012038068A2 (pt) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108997498A (zh) | 2008-12-09 | 2018-12-14 | 霍夫曼-拉罗奇有限公司 | 抗-pd-l1抗体及它们用于增强t细胞功能的用途 |
US20120171694A1 (en) * | 2010-07-30 | 2012-07-05 | Vermillion, Inc. | Predictive markers and biomarker panels for ovarian cancer |
RU2626540C2 (ru) | 2011-04-18 | 2017-07-28 | Диамир, Ллс | Способы обнаружения патологических изменений в органе или системе органов |
US9760760B2 (en) * | 2012-01-19 | 2017-09-12 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Histology recognition to automatically score and quantify cancer grades and individual user digital whole histological imaging device |
US20130203614A1 (en) * | 2012-02-08 | 2013-08-08 | Jerome Galon | Methods for predicting the survival time of a patient suffering from a solid cancer |
AU2013240224A1 (en) * | 2012-03-30 | 2014-10-16 | Sloan-Kettering Institute For Cancer Research | S100A8/A9 as a diagnostic marker and a therapeutic target |
US20150218650A1 (en) * | 2012-08-06 | 2015-08-06 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and kits for screening patients with a cancer |
DK2888591T3 (da) * | 2012-08-21 | 2019-01-02 | Medetect Ab | Fremgangsmåde til forbedret celleidentifikation |
WO2014039654A1 (en) * | 2012-09-06 | 2014-03-13 | Joslin Diabetes Center, Inc. | Isolation and characterization of muscle regenerating cells |
WO2014114595A1 (en) | 2013-01-23 | 2014-07-31 | Roche Glycart Ag | Predictive biomarker for cancer treatment with adcc-enhanced antibodies |
WO2014173860A1 (en) * | 2013-04-23 | 2014-10-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the responsiveness of a patient affected with a tumor to a treatment with a combination of iron uptake inhibitor and vitamin d receptor agonist |
WO2015073972A1 (en) | 2013-11-18 | 2015-05-21 | Diamir, Llc | METHODS OF USING mIRNAs FROM BODILY FLUIDS FOR DETECTION AND MONITORING OF PARKINSON'S DISEASE (PD) |
WO2015117164A1 (en) * | 2014-02-03 | 2015-08-06 | Memorial Sloan-Kettering Cancer Center | Tumor-associated macrophages and methods and compositions for targeting cancer therapy and identifying potential responders |
ES2701092T5 (es) * | 2014-02-24 | 2022-05-12 | Ventana Med Syst Inc | Procedimientos, kits y sistemas para puntuar la respuesta inmunitaria al cáncer por detección simultánea de CD3, CD8, CD20 y FOXP3 |
EP3215852A4 (en) * | 2014-11-05 | 2018-04-04 | The Regents of the University of California | Methods for stratifying non-responders to therapies that block pd1/pdl1 axis |
KR101751929B1 (ko) * | 2015-01-05 | 2017-06-28 | 서울대학교 산학협력단 | 신규 간암 환자의 소라페닙 저항성 예측 마커 |
US20160258848A1 (en) * | 2015-03-04 | 2016-09-08 | Agilent Technologies, Inc. | Methods and compositions for multiplex tissue section analyses using visible and non-visible labels |
EP3839510A3 (en) * | 2015-04-17 | 2021-08-25 | Merck Sharp & Dohme Corp. | Blood-based biomarkers of tumor sensitivity to pd-1 antagonists |
US10839509B2 (en) | 2015-07-10 | 2020-11-17 | 3Scan Inc. | Spatial multiplexing of histological stains |
EP3341732B1 (en) * | 2015-08-27 | 2023-07-12 | INSERM - Institut National de la Santé et de la Recherche Médicale | Methods for predicting the survival time of patients suffering from a lung cancer |
AU2016341306B2 (en) * | 2015-10-23 | 2022-10-27 | Novartis Ag | Computer processes behind an enhanced version of aqua |
US10975436B2 (en) | 2016-01-05 | 2021-04-13 | Diamir, Llc | Methods of using miRNA from bodily fluids for diagnosis and monitoring of neurodevelopmental disorders |
WO2017165458A1 (en) | 2016-03-21 | 2017-09-28 | Diamir, Llc | Methods of using mirnas from bodily fluids for detection and differentiation of neurodegenerative diseases |
WO2017189526A1 (en) * | 2016-04-25 | 2017-11-02 | Musc Foundation For Research Development | Activated cd26-high immune cells and cd26-negative immune cells and uses thereof |
CN106084114B (zh) * | 2016-06-08 | 2017-11-10 | 渤海大学 | 一种恩诺沙星适配体/分子印迹杂化型上转换荧光探针的制备方法 |
US9990713B2 (en) * | 2016-06-09 | 2018-06-05 | Definiens Ag | Detecting and visualizing correlations between measured correlation values and correlation reference values of a pathway |
EP3500290A4 (en) * | 2016-08-19 | 2020-04-29 | Brooklyn Immunotherapeutics LLC | USES OF PD-1 / PD-L1 INHIBITORS AND / OR CTLA-4 INHIBITORS WITH A BIOLOGICAL CONTAINING MULTIPLE CYTOKINE COMPONENTS TO TREAT CANCER |
EP3515495A4 (en) * | 2016-09-26 | 2020-08-26 | Ensemble Group Holdings | METHOD OF EVALUATION AND TREATMENT OF CANCER IN HUMANS WITH DYSREGULATED LYMPHATIC SYSTEMS |
WO2018102567A1 (en) * | 2016-12-01 | 2018-06-07 | Yale University | Prediction of response to immune-modulatory therapies |
US20200147210A1 (en) * | 2017-05-11 | 2020-05-14 | The General Hospital Corporation | Methods and compositions of use of cd8+ tumor infiltrating lymphocyte subtypes and gene signatures thereof |
US20180357361A1 (en) * | 2017-06-13 | 2018-12-13 | Feliks Frenkel | Systems and methods for identifying responders and non-responders to immune checkpoint blockade therapy |
EP3649250A4 (en) * | 2017-07-05 | 2021-03-24 | The Regents of the University of California | ASSAY FOR PREOPERATIVE PREDICTION OF RESTORATION OF ORGAN FUNCTION |
US10781487B2 (en) | 2017-07-24 | 2020-09-22 | Diamir, Llc | miRNA-based methods for detecting and monitoring aging |
US10950424B2 (en) * | 2017-09-25 | 2021-03-16 | Bruker Daltonik, Gmbh | Method for monitoring the quality of mass spectrometric imaging preparation workflows |
US20210341483A1 (en) * | 2017-11-30 | 2021-11-04 | Singapore Health Services Pte. Ltd. | System and method for classifying cancer patients into appropriate cancer treatment groups and compounds for treating the patient |
EP3887548A1 (en) * | 2018-11-30 | 2021-10-06 | GBG Forschungs GmbH | Method for predicting the response to cancer immunotherapy in cancer patients |
CN109655624A (zh) * | 2019-02-11 | 2019-04-19 | 臻和(北京)科技有限公司 | 一种用于预测癌症免疫治疗效果的标志物及其应用、试剂盒和试剂盒的制备方法 |
WO2020245155A1 (en) * | 2019-06-03 | 2020-12-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for modulating a treatment regimen |
CN110895280B (zh) * | 2019-12-03 | 2022-11-18 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | 用于预测鼻咽癌转移的免疫评分及其应用 |
WO2021156360A1 (en) * | 2020-02-05 | 2021-08-12 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for discontinuing a treatment with a tyrosine kinase inhibitor (tki) |
CN115398556A (zh) * | 2020-02-07 | 2022-11-25 | 赛诺菲 | 用于预测患者反应的系统和方法 |
US20210277345A1 (en) * | 2020-03-06 | 2021-09-09 | Tomoyuki Aratani | Cell-containing container, method for evaluating test substance, and method for manufacturing cell-containing container |
EP4321625A1 (en) * | 2021-04-06 | 2024-02-14 | Industry Foundation of Chonnam National University | Method for predicting prognosis and responsiveness to anticancer therapy of cancer patients |
CN113358872B (zh) * | 2021-06-03 | 2022-10-21 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | 用于评估肿瘤免疫治疗疗效的标志物组及系统 |
CN114622023A (zh) * | 2021-09-09 | 2022-06-14 | 四川省肿瘤医院 | 一种预测肿瘤化疗联合免疫治疗疗效的标志物及其应用 |
CN114019163B (zh) * | 2021-11-02 | 2024-07-23 | 复旦大学附属中山医院 | 基于活化b细胞表达的结肠癌预后诊断用标记物及其用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6711283B1 (en) * | 2000-05-03 | 2004-03-23 | Aperio Technologies, Inc. | Fully automatic rapid microscope slide scanner |
EP1428169B1 (en) * | 2002-02-22 | 2017-01-18 | Olympus America Inc. | Focusable virtual microscopy apparatus and method |
WO2005100606A2 (en) * | 2004-04-09 | 2005-10-27 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
EP1777523A1 (en) | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
GB0601509D0 (en) * | 2006-01-26 | 2006-03-08 | Maddison John | Method And Apparatus For Aligning Microscope Images |
-
2011
- 2011-09-20 US US13/825,729 patent/US9726676B2/en active Active
- 2011-09-20 HU HUE11773381A patent/HUE051674T2/hu unknown
- 2011-09-20 PL PL11773381T patent/PL2619576T3/pl unknown
- 2011-09-20 DK DK11773381.6T patent/DK2619576T3/da active
- 2011-09-20 EP EP11773381.6A patent/EP2619576B1/en active Active
- 2011-09-20 SI SI201131914T patent/SI2619576T1/sl unknown
- 2011-09-20 PT PT117733816T patent/PT2619576T/pt unknown
- 2011-09-20 ES ES11773381T patent/ES2816625T3/es active Active
- 2011-09-20 WO PCT/EP2011/004710 patent/WO2012038068A2/en active Application Filing
-
2020
- 2020-09-07 HR HRP20201424TT patent/HRP20201424T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
WO2012038068A3 (en) | 2012-05-31 |
US9726676B2 (en) | 2017-08-08 |
DK2619576T3 (da) | 2020-09-07 |
WO2012038068A8 (en) | 2013-11-28 |
HUE051674T2 (hu) | 2021-03-29 |
US20130330325A1 (en) | 2013-12-12 |
WO2012038068A2 (en) | 2012-03-29 |
SI2619576T1 (sl) | 2021-03-31 |
PL2619576T3 (pl) | 2021-07-05 |
ES2816625T3 (es) | 2021-04-05 |
EP2619576B1 (en) | 2020-06-10 |
HRP20201424T1 (hr) | 2021-02-19 |
EP2619576A2 (en) | 2013-07-31 |
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