RU2744615C2 - Использование 1-метилникотинамида для лечения заболеваний, связанных с c-реактивным белком - Google Patents
Использование 1-метилникотинамида для лечения заболеваний, связанных с c-реактивным белком Download PDFInfo
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- RU2744615C2 RU2744615C2 RU2019104343A RU2019104343A RU2744615C2 RU 2744615 C2 RU2744615 C2 RU 2744615C2 RU 2019104343 A RU2019104343 A RU 2019104343A RU 2019104343 A RU2019104343 A RU 2019104343A RU 2744615 C2 RU2744615 C2 RU 2744615C2
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| US201662363712P | 2016-07-18 | 2016-07-18 | |
| US62/363,712 | 2016-07-18 | ||
| PCT/IB2017/054293 WO2018015861A1 (en) | 2016-07-18 | 2017-07-16 | 1-methylnicotinamide for the treatment of diseases associated with c-reactive protein |
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| RU2019104343A RU2019104343A (ru) | 2020-08-18 |
| RU2019104343A3 RU2019104343A3 (https=) | 2020-09-17 |
| RU2744615C2 true RU2744615C2 (ru) | 2021-03-11 |
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| RU (1) | RU2744615C2 (https=) |
| WO (1) | WO2018015861A1 (https=) |
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| WO2020115765A1 (en) | 2018-12-05 | 2020-06-11 | Celagenex Research (India) Pvt. Ltd. | Novel synergistic composition comprising sirt1 and ampk activators for treating metabolic syndrome |
| CN112294786A (zh) * | 2019-08-01 | 2021-02-02 | 深圳大学 | 一种含乙胺丁醇与他汀类药物的抗结核组合药物 |
| WO2021205341A1 (en) | 2020-04-07 | 2021-10-14 | Pharmena S.A. | 1-methylnicotinamide for the prevention/treatment of inflammatory airway diseases |
| WO2022047730A1 (en) * | 2020-09-04 | 2022-03-10 | Shanghai Pharmaceuticals Holding Co., Ltd. | Methods to treat inflammatory bowel disease |
| EP4213821A2 (en) * | 2020-09-21 | 2023-07-26 | The Regents of the University of California | Immunological effects of metabolites |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2007074406A2 (en) * | 2005-07-11 | 2007-07-05 | Pharmena North America Inc. | Formulations for treatment of lipoprotein abnormalities comprising a statin a statin and a methylnicotinamide derivative |
| US20080249140A1 (en) * | 2005-12-09 | 2008-10-09 | Jacques Gosteli | Quaternary 3 -Amido, N-Methylpyridinium Salts as Anti-Inflammatory Agents |
| US20090118225A1 (en) * | 2007-09-28 | 2009-05-07 | Cortria Corporation | 1-Methyl Nicotinamide and Derivatives for Treatment of Gastric Injury |
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| AT131118B (de) | 1929-04-19 | 1933-01-10 | Ig Farbenindustrie Ag | Verfahren zur Darstellung von N-Methylpyridiniumchlorid. |
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3614408A (en) | 1969-02-20 | 1971-10-19 | British Petroleum Co | Waveform analyzing system, particularly for chromatographs, wherein the waveform is integrated between selected peaks and valleys |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4115390A (en) | 1977-08-19 | 1978-09-19 | Nardi John C | Method for the preparation of 1-alkyl pyridinium chlorides |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5007790A (en) | 1989-04-11 | 1991-04-16 | Depomed Systems, Inc. | Sustained-release oral drug dosage form |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US7030152B1 (en) | 1997-04-02 | 2006-04-18 | The Brigham And Women's Hospital, Inc. | Systematic inflammatory markers as diagnostic tools in the prevention of atherosclerotic diseases and as tools to aid in the selection of agents to be used for the prevention and treatment of atherosclerotic disease |
| PL364348A1 (en) * | 2004-01-12 | 2005-07-25 | PHARMENA Sp.z o.o. | Application of quaternary pyridine salts as vessel protection agent |
| WO2006024545A1 (en) * | 2004-09-03 | 2006-03-09 | Stichting Voor De Technische Wetenschappen | Fused bicyclic natural compounds and their use as inhibitors of parp and parp-mediated inflammatory processes |
| DK2026651T3 (da) * | 2006-03-08 | 2013-07-08 | Cortria Corp | Kombinationsterapi med ikke-selektive COX-inhibitorer til forebyggelse af COX-relaterede maveskader |
| PL381862A1 (pl) * | 2007-02-28 | 2008-09-01 | Trigendo Spółka Z Ograniczoną Odpowiedzialnością | Zastosowanie związków pirydyniowych i sposób leczenia |
| PL2211858T3 (pl) * | 2007-10-12 | 2015-06-30 | Politechnika Lodzka | Zastosowanie czwartorzędowych soli pirydyniowych do hamowania przerzutów nowotworowych |
| WO2009137527A1 (en) * | 2008-05-06 | 2009-11-12 | Cortria Corporation | 1-methylnicotinamide analogs |
| WO2011047358A1 (en) * | 2009-10-15 | 2011-04-21 | Crescendo Bioscience | Biomarkers and methods for measuring and monitoring inflammatory disease activity |
| PL226999B1 (pl) * | 2013-06-11 | 2017-10-31 | Univ Jagiellonski | Azotan (III) 3 -karbamoilo -1-metylopirydyniowy, sposób jego otrzymywania izastosowanie |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007074406A2 (en) * | 2005-07-11 | 2007-07-05 | Pharmena North America Inc. | Formulations for treatment of lipoprotein abnormalities comprising a statin a statin and a methylnicotinamide derivative |
| US20080249140A1 (en) * | 2005-12-09 | 2008-10-09 | Jacques Gosteli | Quaternary 3 -Amido, N-Methylpyridinium Salts as Anti-Inflammatory Agents |
| US20090118225A1 (en) * | 2007-09-28 | 2009-05-07 | Cortria Corporation | 1-Methyl Nicotinamide and Derivatives for Treatment of Gastric Injury |
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| Е.В. Хоролец и др. Диагностическая значимость С-реактивного белка в генезе патологии сердечно-сосудистой системы / Журнал фундаментальной медицины и биологии, 2013, N 1. * |
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| PL3484475T3 (pl) | 2024-03-11 |
| FI3484475T3 (fi) | 2023-12-12 |
| MX389845B (es) | 2025-03-20 |
| ES2967074T3 (es) | 2024-04-25 |
| RU2019104343A3 (https=) | 2020-09-17 |
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| US20190282560A1 (en) | 2019-09-19 |
| RU2019104343A (ru) | 2020-08-18 |
| AU2017298648B2 (en) | 2023-05-11 |
| JP2019521160A (ja) | 2019-07-25 |
| CA3030805A1 (en) | 2018-01-25 |
| DK3484475T3 (da) | 2023-11-27 |
| AU2017298648A1 (en) | 2019-01-31 |
| EP3484475B1 (en) | 2023-09-27 |
| WO2018015861A1 (en) | 2018-01-25 |
| EP3484475A1 (en) | 2019-05-22 |
| CN109562108A (zh) | 2019-04-02 |
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