RU2730656C2 - Маломасштабный способ культивирования суспендированных клеток - Google Patents
Маломасштабный способ культивирования суспендированных клеток Download PDFInfo
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- RU2730656C2 RU2730656C2 RU2017140920A RU2017140920A RU2730656C2 RU 2730656 C2 RU2730656 C2 RU 2730656C2 RU 2017140920 A RU2017140920 A RU 2017140920A RU 2017140920 A RU2017140920 A RU 2017140920A RU 2730656 C2 RU2730656 C2 RU 2730656C2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0062—General methods for three-dimensional culture
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2511/00—Cells for large scale production
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- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
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- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU92727 | 2015-05-29 | ||
| LU92727 | 2015-05-29 | ||
| EP16151811 | 2016-01-19 | ||
| EP16151811.3 | 2016-01-19 | ||
| PCT/EP2016/061763 WO2016193083A1 (en) | 2015-05-29 | 2016-05-25 | Small scale cultivation method for suspension cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2017140920A RU2017140920A (ru) | 2019-07-01 |
| RU2017140920A3 RU2017140920A3 (enExample) | 2019-07-17 |
| RU2730656C2 true RU2730656C2 (ru) | 2020-08-24 |
Family
ID=56108615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017140920A RU2730656C2 (ru) | 2015-05-29 | 2016-05-25 | Маломасштабный способ культивирования суспендированных клеток |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20180135091A1 (enExample) |
| EP (1) | EP3303557B1 (enExample) |
| JP (1) | JP6737813B2 (enExample) |
| KR (1) | KR20180010200A (enExample) |
| CN (1) | CN108138128A (enExample) |
| AU (1) | AU2016272566A1 (enExample) |
| BR (1) | BR112017023624A2 (enExample) |
| CA (1) | CA2985435A1 (enExample) |
| RU (1) | RU2730656C2 (enExample) |
| WO (1) | WO2016193083A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016272566A1 (en) | 2015-05-29 | 2017-11-23 | Glycotope Gmbh | Small scale cultivation method for suspension cells |
| EP3472338B1 (en) | 2016-06-20 | 2024-05-22 | Octapharma AG | Means and methods for modifying multiple alleles |
| EP3522128B1 (en) * | 2016-09-29 | 2021-01-27 | Coaido Inc. | Disaster emergency system for simultaneously calling telephones in region |
| JP7317466B2 (ja) * | 2017-12-12 | 2023-07-31 | 株式会社日立製作所 | 細胞株及び培養条件のスクリーニング方法、及びその装置 |
| CN111139216B (zh) * | 2018-11-01 | 2024-09-03 | 上海药明生物技术有限公司 | 高通量、自动化的细胞连续培养方法及其应用 |
| US20220177818A1 (en) * | 2019-04-01 | 2022-06-09 | The Automation Partnership (Cambridge ) Ltd. | Operation process for a cell cultivation system |
| CN113795885A (zh) * | 2019-05-08 | 2021-12-14 | 齐默尔根公司 | 缩小参数以设计在小规模下的微生物的实验及板模型以改进对在更大规模下的性能的预测 |
| BR112022000061A2 (pt) * | 2019-07-01 | 2022-05-24 | Ology Bioservices Inc | Método para o cultivo de células aderentes em um bioreator multiparalelo |
| CN118064651B (zh) * | 2024-03-11 | 2025-03-11 | 上海迈邦生物科技有限公司 | 一种细胞灌流培养体系维持稳态的方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0599651A2 (en) * | 1992-11-25 | 1994-06-01 | National Research Council Of Canada | Bioreactor for the perfusion culture of cells |
| WO2012085162A1 (en) * | 2010-12-21 | 2012-06-28 | Glycotope Gmbh | Methods for culturing human myeloid leukaemia cells and cells derived therefrom |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2997771B2 (ja) * | 1998-06-29 | 2000-01-11 | 金沢大学長 | 細胞の懸濁培養方法 |
| US20040185534A1 (en) * | 2000-10-02 | 2004-09-23 | Knudsen Ida Molgaard | Industrial-scale serum-free production of recombinant proteins in mammalian cells |
| US20040185535A1 (en) | 2003-03-21 | 2004-09-23 | Giles Wilson | Industrial-scale serum-free production of recombinant FVII in mammalian cells |
| WO2007071072A1 (en) | 2005-12-22 | 2007-06-28 | Corporation De L'ecole Polytechnique De Montreal | High-rate perfusion bioreactor |
| CN101490239A (zh) * | 2006-07-14 | 2009-07-22 | 帝斯曼知识产权资产管理有限公司 | 改进的细胞培养方法 |
| EP2014760A1 (en) | 2007-06-13 | 2009-01-14 | CMC Biopharmaceuticals A/S | A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process |
| NO2501822T3 (enExample) * | 2009-11-17 | 2018-01-13 | ||
| EP2599651A1 (de) | 2011-12-01 | 2013-06-05 | Magna E-Car Systems GmbH & Co OG | Heiz-/Kühlsystem für eine Batterie eines Kraftfahrzeugs sowie Betriebsverfahren hierfür |
| CN102690781B (zh) * | 2012-04-28 | 2014-04-30 | 苏州金盟生物技术有限公司 | 一种灌流式细胞培养的培养基更换方法 |
| CN104195187B (zh) | 2014-08-01 | 2018-02-16 | 润科生物工程（福建）有限公司 | 沉降‑逆灌流‑放流偶联制备富含dha油脂的方法及其专用细胞沉降槽 |
| AU2016272566A1 (en) | 2015-05-29 | 2017-11-23 | Glycotope Gmbh | Small scale cultivation method for suspension cells |
-
2016
- 2016-05-25 AU AU2016272566A patent/AU2016272566A1/en not_active Abandoned
- 2016-05-25 JP JP2017560971A patent/JP6737813B2/ja active Active
- 2016-05-25 CA CA2985435A patent/CA2985435A1/en not_active Abandoned
- 2016-05-25 EP EP16727348.1A patent/EP3303557B1/en not_active Revoked
- 2016-05-25 BR BR112017023624A patent/BR112017023624A2/pt not_active Application Discontinuation
- 2016-05-25 RU RU2017140920A patent/RU2730656C2/ru active
- 2016-05-25 US US15/574,250 patent/US20180135091A1/en not_active Abandoned
- 2016-05-25 CN CN201680030077.0A patent/CN108138128A/zh active Pending
- 2016-05-25 WO PCT/EP2016/061763 patent/WO2016193083A1/en not_active Ceased
- 2016-05-25 KR KR1020177034153A patent/KR20180010200A/ko not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0599651A2 (en) * | 1992-11-25 | 1994-06-01 | National Research Council Of Canada | Bioreactor for the perfusion culture of cells |
| WO2012085162A1 (en) * | 2010-12-21 | 2012-06-28 | Glycotope Gmbh | Methods for culturing human myeloid leukaemia cells and cells derived therefrom |
Non-Patent Citations (1)
| Title |
|---|
| WOODSIDE S.M., et al. "Mammalian cell retention devices for stirred perfusion bioreactors", Cytotechnology.1998; 28:163-175;. ГОРДЕЕВ А.А. "Методы скрининга живых клеток", Успехи биологической химии. 2018; 58:173-222. * |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2017140920A (ru) | 2019-07-01 |
| RU2017140920A3 (enExample) | 2019-07-17 |
| JP6737813B2 (ja) | 2020-08-12 |
| CA2985435A1 (en) | 2016-12-08 |
| EP3303557A1 (en) | 2018-04-11 |
| US20180135091A1 (en) | 2018-05-17 |
| AU2016272566A1 (en) | 2017-11-23 |
| EP3303557B1 (en) | 2021-05-05 |
| KR20180010200A (ko) | 2018-01-30 |
| CN108138128A (zh) | 2018-06-08 |
| JP2018516077A (ja) | 2018-06-21 |
| WO2016193083A1 (en) | 2016-12-08 |
| BR112017023624A2 (pt) | 2018-07-17 |
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