CA2985435A1 - Small scale cultivation method for suspension cells - Google Patents

Small scale cultivation method for suspension cells

Info

Publication number
CA2985435A1
CA2985435A1 CA2985435A CA2985435A CA2985435A1 CA 2985435 A1 CA2985435 A1 CA 2985435A1 CA 2985435 A CA2985435 A CA 2985435A CA 2985435 A CA2985435 A CA 2985435A CA 2985435 A1 CA2985435 A1 CA 2985435A1
Authority
CA
Canada
Prior art keywords
culture
cells
cell
small scale
culture medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2985435A
Other languages
English (en)
French (fr)
Inventor
Steffen Goletz
Rainer Stahn
Steffen KREYE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glycotope GmbH
Original Assignee
Glycotope GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56108615&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2985435(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glycotope GmbH filed Critical Glycotope GmbH
Publication of CA2985435A1 publication Critical patent/CA2985435A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2511/00—Cells for large scale production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2985435A 2015-05-29 2016-05-25 Small scale cultivation method for suspension cells Abandoned CA2985435A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
LU92727 2015-05-29
LU92727 2015-05-29
EP16151811.3 2016-01-19
EP16151811 2016-01-19
PCT/EP2016/061763 WO2016193083A1 (en) 2015-05-29 2016-05-25 Small scale cultivation method for suspension cells

Publications (1)

Publication Number Publication Date
CA2985435A1 true CA2985435A1 (en) 2016-12-08

Family

ID=56108615

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2985435A Abandoned CA2985435A1 (en) 2015-05-29 2016-05-25 Small scale cultivation method for suspension cells

Country Status (10)

Country Link
US (1) US20180135091A1 (enExample)
EP (1) EP3303557B1 (enExample)
JP (1) JP6737813B2 (enExample)
KR (1) KR20180010200A (enExample)
CN (1) CN108138128A (enExample)
AU (1) AU2016272566A1 (enExample)
BR (1) BR112017023624A2 (enExample)
CA (1) CA2985435A1 (enExample)
RU (1) RU2730656C2 (enExample)
WO (1) WO2016193083A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108138128A (zh) 2015-05-29 2018-06-08 葛莱高托普有限公司 用于悬浮细胞的小规模养殖方法
US11713458B2 (en) 2016-06-20 2023-08-01 Octapharma Ag Means and methods for modifying multiple alleles
WO2018062358A1 (ja) * 2016-09-29 2018-04-05 Ｃｏａｉｄｏ株式会社 災害緊急用地域一斉架電システム
JP7317466B2 (ja) * 2017-12-12 2023-07-31 株式会社日立製作所 細胞株及び培養条件のスクリーニング方法、及びその装置
CN111139216B (zh) * 2018-11-01 2024-09-03 上海药明生物技术有限公司 高通量、自动化的细胞连续培养方法及其应用
EP3947632A1 (en) * 2019-04-01 2022-02-09 The Automation Partnership (Cambridge) Ltd. Operation process for a cell cultivation system
US20220328128A1 (en) * 2019-05-08 2022-10-13 Zymergen Inc. Downscaling parameters to design experiments and plate models for micro-organisms at small scale to improve prediction of performance at larger scale
CA3144960A1 (en) * 2019-07-01 2021-01-07 Ology Bioservices, Inc. Method for cultivation of adherent cells in a multiparallel bioreactor
CN118064651B (zh) * 2024-03-11 2025-03-11 上海迈邦生物科技有限公司 一种细胞灌流培养体系维持稳态的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5320963A (en) * 1992-11-25 1994-06-14 National Research Council Of Canada Bioreactor for the perfusion culture of cells
JP2997771B2 (ja) * 1998-06-29 2000-01-11 金沢大学長 細胞の懸濁培養方法
US20040185535A1 (en) 2003-03-21 2004-09-23 Giles Wilson Industrial-scale serum-free production of recombinant FVII in mammalian cells
US20040185534A1 (en) * 2000-10-02 2004-09-23 Knudsen Ida Molgaard Industrial-scale serum-free production of recombinant proteins in mammalian cells
WO2007071072A1 (en) 2005-12-22 2007-06-28 Corporation De L'ecole Polytechnique De Montreal High-rate perfusion bioreactor
CN101490239A (zh) * 2006-07-14 2009-07-22 帝斯曼知识产权资产管理有限公司 改进的细胞培养方法
EP2014760A1 (en) 2007-06-13 2009-01-14 CMC Biopharmaceuticals A/S A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process
DK2501822T3 (da) * 2009-11-17 2017-11-27 Squibb & Sons Llc Fremgangsmåder til forbedret proteinproduktion
US9359427B2 (en) * 2010-12-21 2016-06-07 Glycotope Gmbh Methods for culturing human myeloid leukaemia cells and cells derived therefrom
EP2599651A1 (de) 2011-12-01 2013-06-05 Magna E-Car Systems GmbH & Co OG Heiz-/Kühlsystem für eine Batterie eines Kraftfahrzeugs sowie Betriebsverfahren hierfür
CN102690781B (zh) * 2012-04-28 2014-04-30 苏州金盟生物技术有限公司 一种灌流式细胞培养的培养基更换方法
CN104195187B (zh) 2014-08-01 2018-02-16 润科生物工程（福建）有限公司 沉降‑逆灌流‑放流偶联制备富含dha油脂的方法及其专用细胞沉降槽
CN108138128A (zh) 2015-05-29 2018-06-08 葛莱高托普有限公司 用于悬浮细胞的小规模养殖方法

Also Published As

Publication number Publication date
RU2017140920A (ru) 2019-07-01
WO2016193083A1 (en) 2016-12-08
AU2016272566A1 (en) 2017-11-23
US20180135091A1 (en) 2018-05-17
KR20180010200A (ko) 2018-01-30
EP3303557A1 (en) 2018-04-11
RU2730656C2 (ru) 2020-08-24
BR112017023624A2 (pt) 2018-07-17
EP3303557B1 (en) 2021-05-05
JP2018516077A (ja) 2018-06-21
CN108138128A (zh) 2018-06-08
RU2017140920A3 (enExample) 2019-07-17
JP6737813B2 (ja) 2020-08-12

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20220816