RU2724895C2 - Противомикробная иммуномодуляция - Google Patents
Противомикробная иммуномодуляция Download PDFInfo
- Publication number
- RU2724895C2 RU2724895C2 RU2016147048A RU2016147048A RU2724895C2 RU 2724895 C2 RU2724895 C2 RU 2724895C2 RU 2016147048 A RU2016147048 A RU 2016147048A RU 2016147048 A RU2016147048 A RU 2016147048A RU 2724895 C2 RU2724895 C2 RU 2724895C2
- Authority
- RU
- Russia
- Prior art keywords
- cells
- macrophages
- pathogenic
- infection
- antigenic
- Prior art date
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0266—Klebsiella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461988117P | 2014-05-02 | 2014-05-02 | |
| US61/988,117 | 2014-05-02 | ||
| PCT/CA2015/050377 WO2015164979A1 (en) | 2014-05-02 | 2015-05-01 | Anti-microbial immunomodulation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2020120075A Division RU2020120075A (ru) | 2014-05-02 | 2015-05-01 | Противомикробная иммуномодуляция |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2016147048A RU2016147048A (ru) | 2018-06-05 |
| RU2016147048A3 RU2016147048A3 (enExample) | 2019-02-22 |
| RU2724895C2 true RU2724895C2 (ru) | 2020-06-26 |
Family
ID=54357960
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016147048A RU2724895C2 (ru) | 2014-05-02 | 2015-05-01 | Противомикробная иммуномодуляция |
| RU2020120075A RU2020120075A (ru) | 2014-05-02 | 2015-05-01 | Противомикробная иммуномодуляция |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2020120075A RU2020120075A (ru) | 2014-05-02 | 2015-05-01 | Противомикробная иммуномодуляция |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US10251946B2 (enExample) |
| EP (1) | EP3137108A4 (enExample) |
| JP (1) | JP6632607B2 (enExample) |
| CN (2) | CN106456740B (enExample) |
| AU (2) | AU2015252726B2 (enExample) |
| CA (2) | CA3254723A1 (enExample) |
| RU (2) | RU2724895C2 (enExample) |
| WO (1) | WO2015164979A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8980279B2 (en) * | 2010-07-26 | 2015-03-17 | Qu Biologics | Personalized site-specific immunomodulation |
| JP6632607B2 (ja) * | 2014-05-02 | 2020-01-22 | クー バイオロジックス インク.Qu Biologics Inc. | 抗微生物免疫修飾 |
| WO2017185180A1 (en) | 2016-04-26 | 2017-11-02 | Qu Biologics Inc. | Therapeutically triggering an innate immune response in a target tissue |
| US12491153B2 (en) | 2018-01-03 | 2025-12-09 | Qu Biologics Inc. | Innate targeting of adoptive cellular therapies |
| CN113226342A (zh) * | 2018-10-17 | 2021-08-06 | 西巴克股份有限公司 | 治疗和预防肺部状况的活的生物治疗剂 |
| US12194157B2 (en) | 2020-04-09 | 2025-01-14 | Finncure Oy | Carrier for targeted delivery to a host |
| AU2021252164A1 (en) | 2020-04-09 | 2022-12-15 | Finncure Oy | Mimetic nanoparticles for preventing the spreading and lowering the infection rate of novel coronaviruses |
| WO2022067219A1 (en) * | 2020-09-28 | 2022-03-31 | The Regents Of The University Of Michigan | Methods and compositions for intestinal inflammation |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012012874A1 (en) * | 2010-07-26 | 2012-02-02 | Qu Biologics Inc. | Immunogenic anti-inflammatory compositions |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3928565A (en) | 1971-10-19 | 1975-12-23 | Yuzuru Homma | Pharmaceutical preparation of pseudomonas aeruginosa bacterial component possessing anti-tumor and anti-infection properties |
| JPS5946493B2 (ja) | 1978-03-31 | 1984-11-13 | 株式会社三和化学研究所 | 異種死菌体混合物を有効成分とする抗腫瘍剤 |
| JPS568320A (en) | 1979-07-04 | 1981-01-28 | Chisato Maruyama | Drug for tumor immunotherapy comprising lipopolysaccharide as active constituent |
| JPS56108716A (en) | 1980-01-30 | 1981-08-28 | Sanwa Kagaku Kenkyusho:Kk | Antiviral agent containing different kind dead cell mixture as effective component |
| JPS5839624A (ja) | 1981-09-02 | 1983-03-08 | Meiji Seika Kaisha Ltd | 抗腫瘍剤 |
| JPS6012071A (ja) | 1983-06-30 | 1985-01-22 | 東レ株式会社 | 抗腫瘍作用を有する体液処理剤 |
| US4880626A (en) | 1985-01-18 | 1989-11-14 | Mcmichael John | Immunotherapeutic methods and compositions for the treatment of diseases of viral origin, including acquired immune deficiency syndrome |
| US5292513A (en) | 1992-05-18 | 1994-03-08 | Anthony G. Gristina | Method for nonspecific cellular immune stimulation |
| US5652332A (en) | 1993-03-12 | 1997-07-29 | Xoma | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
| GB9406301D0 (en) | 1994-03-30 | 1994-05-25 | Univ London | Immunotherapeutic agent and its use |
| US6902743B1 (en) | 1995-05-22 | 2005-06-07 | The United States Of America As Represented By The Secretary Of The Army | Therapeutic treatment and prevention of infections with a bioactive material(s) encapuslated within a biodegradable-bio-compatable polymeric matrix |
| US5869057A (en) | 1995-06-07 | 1999-02-09 | Rock; Edwin P. | Recombinant vaccines to break self-tolerance |
| WO1997036614A1 (en) | 1996-03-29 | 1997-10-09 | Terman David S | Polymerized staphylococcal protein a for treatment of diseases |
| US6348586B1 (en) | 1996-07-25 | 2002-02-19 | The Trustees Of Columbia University In The City Of New York | Unique associated Kaposi's sarcoma virus sequences and uses thereof |
| US20020128240A1 (en) | 1996-12-30 | 2002-09-12 | Bone Care International, Inc. | Treatment of hyperproliferative diseases using active vitamin D analogues |
| US6028060A (en) | 1997-01-29 | 2000-02-22 | Vanderbilt University | Treatment of chronic inflammatory diseases with CM101/GBS toxin |
| ES2368824T3 (es) | 1998-03-27 | 2011-11-22 | Oregon Health & Science University | Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos. |
| WO2001056387A1 (en) | 2000-02-01 | 2001-08-09 | Donnell Michael A O | Immunotherapeutic treatment methodology for patients afflicted with superficial bladder cancer who previously failed at least one immunostimulatory therapeutic treatment regimen |
| US20020044948A1 (en) | 2000-03-15 | 2002-04-18 | Samir Khleif | Methods and compositions for co-stimulation of immunological responses to peptide antigens |
| AUPQ761200A0 (en) * | 2000-05-19 | 2000-06-15 | Hunter Immunology Limited | Compositions and methods for treatment of mucosal infections |
| TWI306760B (en) | 2000-08-07 | 2009-03-01 | Abbott Lab | Use of an endothelin et-a receptor antagonist and orally delivered pharmaceutical composition comprising the same |
| US7118740B1 (en) | 2000-09-22 | 2006-10-10 | Mayo Foundation For Medical Education And Research | Method for limiting the growth of cancer cells using an attenuated measles virus |
| FR2816844A1 (fr) | 2000-11-17 | 2002-05-24 | Pf Medicament | Domaine periplasmique d'une proteine omp d'enterobacterie et son utilisation comme porteur et/ou adjuvant |
| GB2370770B (en) | 2001-01-03 | 2005-06-01 | Simon Connolly | Uses of Streptococcus Vaccines |
| FR2822071B1 (fr) | 2001-03-15 | 2005-07-01 | Pf Medicament | Utilisation d'une fraction membranaire de bacteries a gram negatif pour induire la maturation des cellules dendritiques |
| EP1379224B2 (en) | 2001-03-29 | 2013-10-02 | Synergy Pharmaceuticals, Inc. | Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis |
| US7273602B2 (en) | 2001-07-19 | 2007-09-25 | Akira Hayashi | Immunotherapy for humans |
| EP1281767A3 (en) | 2001-07-31 | 2003-05-28 | Aladar A. Szalay | Light emitting microorganisms and cells for diagnosis and therapy of tumors |
| AU2002353366A1 (en) | 2001-12-10 | 2003-06-23 | Bakulesh Mafatlal Khamar | The process of manufacturing a pharmaceutical composition useful for management of cancer |
| CN1602199B (zh) | 2001-12-11 | 2012-04-04 | 巴斯德研究院 | 用于治疗包含免疫失调的疾病的革兰氏阳性菌制剂 |
| WO2003063593A1 (en) | 2002-01-28 | 2003-08-07 | Vion Pharmaceuticals, Inc. | Methods for treating cancer by administering tumor-targetted bacteria and an immunomodulatory agent |
| WO2003068812A2 (de) | 2002-02-15 | 2003-08-21 | Agelab Pharma Gmbh | Immunmodulierendes peptid aus s. aureus enterotoxin b |
| MXPA04012443A (es) | 2002-06-11 | 2005-04-19 | Glaxosmithkline Biolog Sa | Composiciones inmunogenicas. |
| JP4618970B2 (ja) | 2002-08-02 | 2011-01-26 | マルホ株式会社 | 肛門圧低下外用剤 |
| IL152127A0 (en) | 2002-10-06 | 2003-05-29 | Bio Balance Corp | Probiotic compositions for the treatment of inflammatory bowel disease |
| ES2397836T3 (es) | 2003-01-21 | 2013-03-11 | Yeda Research And Development Co., Ltd. | Copolímero 1 para el tratamiento de enfermedades inflamatorias del intestino |
| AR043692A1 (es) | 2003-02-06 | 2005-08-10 | Novartis Ag | 2-cianopirrolopirimidinas y sus usos farmaceuticos |
| MXPA05011409A (es) | 2003-04-23 | 2005-12-12 | Medarex Inc | Composiciones y metodos para la terapia de enfermedad inflamatoria intestinal. |
| WO2005049056A2 (en) | 2003-11-14 | 2005-06-02 | Ucl Biomedica Plc | Immune modulator comprising whole cell rhodococcus, gordonia, nocardia, dietzia, tsukamurella or nocardioides bacteria |
| US20050175630A1 (en) | 2003-12-23 | 2005-08-11 | Eyal Raz | Immunogenic compositions and methods of use thereof |
| EP1586330A1 (en) | 2004-04-16 | 2005-10-19 | Georg-August-Universität Göttingen | Vaccination against malignant melanoma |
| US9107864B2 (en) | 2004-06-07 | 2015-08-18 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to treat cancers |
| WO2008049231A1 (en) | 2006-10-27 | 2008-05-02 | Harold David Gunn | Tissue targeted antigenic activation of the immune response to treat cancers |
| US8034359B2 (en) * | 2004-06-07 | 2011-10-11 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to cancers |
| CA2611377C (en) | 2004-06-07 | 2019-04-09 | Harold David Gunn | Bacterial compositions for the treatment of cancer |
| US8501198B2 (en) * | 2004-06-07 | 2013-08-06 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to treat cancers |
| US8029777B2 (en) | 2004-08-13 | 2011-10-04 | Marshall Barry J | Helicobacter system and uses thereof |
| JP5234445B2 (ja) | 2004-10-05 | 2013-07-10 | 源一郎 杣 | 薬剤 |
| WO2007136719A2 (en) | 2006-05-18 | 2007-11-29 | Biobalance Llc | Biotherapeutic compositions comprising probiotic escherichia coli and uses thereof |
| CN101573134B (zh) | 2006-08-28 | 2013-03-06 | 李季男 | 抗感染候选药物 |
| CA2997459C (en) | 2006-10-27 | 2020-09-22 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to cancers |
| US8333977B2 (en) | 2007-07-23 | 2012-12-18 | Vaccine Research International Plc | Inactivated staphylococcal whole-cell vaccine |
| US8178340B2 (en) | 2007-08-16 | 2012-05-15 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Human specific Escherichia coli strains |
| HUP0700552A2 (en) | 2007-08-27 | 2009-03-30 | Janos Dr Feher | Method and composition inhibiting inflammation |
| WO2010068413A1 (en) | 2008-11-25 | 2010-06-17 | Emergent Product Development Gaithersburg Inc. | Chlamydia vaccine comprising htra polypeptides |
| CN101954076A (zh) * | 2009-04-27 | 2011-01-26 | 免疫制剂美国公司 | 自身免疫性肝炎的免疫疗法和预防 |
| US8980279B2 (en) * | 2010-07-26 | 2015-03-17 | Qu Biologics | Personalized site-specific immunomodulation |
| US9974848B2 (en) * | 2013-11-14 | 2018-05-22 | Duke University | Tetanus toxoid and CCL3 improve DC vaccines |
| JP6632607B2 (ja) * | 2014-05-02 | 2020-01-22 | クー バイオロジックス インク.Qu Biologics Inc. | 抗微生物免疫修飾 |
-
2015
- 2015-05-01 JP JP2017508718A patent/JP6632607B2/ja active Active
- 2015-05-01 EP EP15786308.5A patent/EP3137108A4/en active Pending
- 2015-05-01 RU RU2016147048A patent/RU2724895C2/ru active
- 2015-05-01 US US15/308,302 patent/US10251946B2/en active Active
- 2015-05-01 AU AU2015252726A patent/AU2015252726B2/en not_active Ceased
- 2015-05-01 CA CA3254723A patent/CA3254723A1/en active Pending
- 2015-05-01 RU RU2020120075A patent/RU2020120075A/ru unknown
- 2015-05-01 CN CN201580030591.XA patent/CN106456740B/zh active Active
- 2015-05-01 CN CN202110547299.2A patent/CN113855791B/zh active Active
- 2015-05-01 CA CA2947631A patent/CA2947631A1/en active Pending
- 2015-05-01 WO PCT/CA2015/050377 patent/WO2015164979A1/en not_active Ceased
-
2019
- 2019-01-31 US US16/264,040 patent/US10946083B2/en active Active
-
2020
- 2020-12-01 AU AU2020281030A patent/AU2020281030B2/en not_active Ceased
-
2021
- 2021-01-21 US US17/154,536 patent/US11819543B2/en active Active
-
2023
- 2023-10-12 US US18/379,422 patent/US20240091330A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012012874A1 (en) * | 2010-07-26 | 2012-02-02 | Qu Biologics Inc. | Immunogenic anti-inflammatory compositions |
Non-Patent Citations (4)
| Title |
|---|
| Cross AS et al. Active immunization with a detoxified Escherichia coli J5 lipopolysaccharide group B meningococcal outer membrane protein complex vaccine protects animals from experimental sepsis //J Infect Dis. 2001 Apr 1;183(7):1079-86. * |
| Cross AS et al. Active immunization with a detoxified Escherichia coli J5 lipopolysaccharide group B meningococcal outer membrane protein complex vaccine protects animals from experimental sepsis //J Infect Dis. 2001 Apr 1;183(7):1079-86. Leen Moens et al. Cross-Protective Immunity against Heterologous Streptococcus pneumoniae // Infect Immun. 2012 May; 80(5): 1944-1945. Wang E et al. Pulmonary and systemic host response to Streptococcus pneumoniae and Klebsiella pneumoniae bacteremia in normal and immunosuppressed mice //Infect Immun. 2001 Sep;69(9):5294-304. * |
| Leen Moens et al. Cross-Protective Immunity against Heterologous Streptococcus pneumoniae // Infect Immun. 2012 May; 80(5): 1944-1945. * |
| Wang E et al. Pulmonary and systemic host response to Streptococcus pneumoniae and Klebsiella pneumoniae bacteremia in normal and immunosuppressed mice //Infect Immun. 2001 Sep;69(9):5294-304. * |
Also Published As
| Publication number | Publication date |
|---|---|
| US10946083B2 (en) | 2021-03-16 |
| CN113855791B (zh) | 2024-11-19 |
| RU2016147048A3 (enExample) | 2019-02-22 |
| JP2017514895A (ja) | 2017-06-08 |
| AU2020281030B2 (en) | 2024-08-08 |
| US20240091330A1 (en) | 2024-03-21 |
| AU2015252726B2 (en) | 2020-12-24 |
| EP3137108A1 (en) | 2017-03-08 |
| US10251946B2 (en) | 2019-04-09 |
| JP6632607B2 (ja) | 2020-01-22 |
| CN106456740B (zh) | 2021-06-08 |
| US20170087237A1 (en) | 2017-03-30 |
| RU2020120075A (ru) | 2020-07-03 |
| CA3254723A1 (en) | 2025-04-15 |
| WO2015164979A1 (en) | 2015-11-05 |
| US11819543B2 (en) | 2023-11-21 |
| RU2016147048A (ru) | 2018-06-05 |
| AU2015252726A1 (en) | 2016-11-10 |
| CN106456740A (zh) | 2017-02-22 |
| US20190247484A1 (en) | 2019-08-15 |
| US20210138057A1 (en) | 2021-05-13 |
| EP3137108A4 (en) | 2017-09-27 |
| CA2947631A1 (en) | 2015-11-05 |
| AU2020281030A1 (en) | 2021-01-07 |
| CN113855791A (zh) | 2021-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2724895C2 (ru) | Противомикробная иммуномодуляция | |
| EP3235506B1 (en) | Immunogenic anti-inflammatory compositions | |
| AU2011200580B2 (en) | Bacterial compositions for the treatment of cancer | |
| US20200121784A1 (en) | Tissue Targeted Antigenic Activation of the Immune Response to Treat Cancers | |
| CN105816865A (zh) | 免疫原性抗炎组合物 | |
| BRPI0607774A2 (pt) | uso de uma composiÇço, e, composiÇço para uso na estimulaÇço de uma resposta imune contra mpt em um animal | |
| BR112013001794B1 (pt) | Uso de uma composição anti-inflamatória |