RU2706694C1 - Preparation for treating and preventing skin diseases of infectious etiology of cattle and small cattle, pigs based on copper chelates - Google Patents

Abstract

FIELD: veterinary science.SUBSTANCE: invention refers to veterinary science, particularly to a preparation for treating and preventing skin diseases of infectious etiology of cattle and small cattle, pigs based on copper chelates in the form of an aerosol spray. Preparation contains following components in following proportions, %: copper chelate – 20–30, lentex M4 -30–40, lentex B352R – 30–40, dye – 0.01–0.05.EFFECT: invention provides higher clinical effectiveness and prevention.1 cl, 1 ex, 4 tbl

Description

The drug belongs to the field of veterinary medicine, in particular to the substances used for the treatment and prevention of inflammatory, purulent-necrotic, ulcerative processes of infectious etiology that affect the skin and skin, including the distal extremities of farm animals: cattle and small cattle, pigs .

Diseases of the skin and skin are widespread and cause significant economic damage to livestock, due to the early culling of sick animals and a significant decrease in their mass and productivity (from 20 to 50%), reproductive ability. Such diseases include finger dermatitis, interdigital dermatitis, interdigital necrobacillosis, crumb erosion, eczema, skin dermatitis, in pigs also, traumatic purulent pododermatitis, crumb phlegmon, corolla.

These diseases develop according to a similar type and, in particular, have a similar microbial component and treatment methods, which allows us to consider them in combination.

There is a gel for hoofs Solka Hoofgel, which has antibacterial and wound healing properties (Zemlyankin V.V. et al., Improving the efficiency of treatment of cows in Mortellaro's disease, Bulletin of the Ulyanovsk State Agricultural Academy, 2018, No. 1 (41), pp. 86-91). As the active components of the gel, metal chelating compounds are used in the ratio: zinc (3.27%) and copper (3.3%) and organic acids. The gel showed high therapeutic efficacy, however, data on performance indicators vary. The gel is applied to the affected area of the hoof after preliminary fixation of the diseased limb and clearing, removing necrotic tissue, washing the hoof and drying. After applying the gel to fix the limb, it is necessary to wait until the gel has completely dried - a few minutes.

The objective of the invention is the creation of a drug in the form of an aerosol for the effective treatment of infectious and non-infectious diseases of the skin and skin in farm animals: cattle and small cattle, pigs.

This is achieved by preparing the drug in the form of an aerosol spray containing in its composition the following components in such proportions,%:

Copper chelate 20-30 Lentex M4 35 30-40 Lentex B352R 35 30-40 Dye 0.01-0.05

The drug for the treatment and prevention of skin and skin diseases in the form of an aerosol has a bactericidal, anti-inflammatory, drying and wound healing effect.

The drug is prepared by thoroughly mixing the components to achieve a uniform consistency.

The drug is a homogeneous clear liquid with a blue tint.

The drug is applied using a spray gun with a directed dispersed stream to the affected areas of the skin, reaching a full dense coating layer. In severe tissue damage, the use of an immobilizing dressing is necessary.

The drug can be used only at positive temperatures (from 0 degrees). All used components of the drug are widely represented on the country's market and are not expensive, that is, the invention is available for every household.

Execution example

At the farm of LLC UK Green Valley Group of Companies 4 groups of animals were formed for diseases with different stages of pathological processes, interdigital dermatitis - 20 animals, interdigital necrobacillosis - 10 animals, crumb erosion - 6 animals and skin eczema - 20 animals were recorded.

For each group, treatment was applied with the same concentration of the drug according to the scheme: 1 day - treatment; 3 day - inspection; Day 5 - inspection, processing as necessary; Day 7 - inspection.

Results:

1. Interdigital dermatitis

2. Interdigital necrobacillosis

3. Erosion of the crumb

4. Eczema skin

Thus, the drug is universal for the treatment of diseases of the skin and skin of farm animals, infectious and non-infectious etiology, showing its high therapeutic efficacy in experimental use.

Information sources

1. Kovalenko A.M. Development and testing of agents against Montellaro cattle disease / A.M. Kovalenko, P.M. Anisko // Bulletin of the Kursk State Agricultural Academy. - No. 5, 2017. - p. 28-31.

2. Yavnikov N.V. Testing the drug based on silver nanoparticles for the treatment of purulent-necrotic lesions of the distal extremities of cows in a dairy complex / N.V. Yavnikov, A.M. Kovalenko, P.M. Anisko, V.A. Kuzmin, A.V. Tsyganov, N.P. Ponomarenko // Hippology and Veterinary Medicine. - St. Petersburg., 2018. - N 1. - p. 93-98.

3. RU 2035183 C1, A61K 35/78 (1995.01), A61K 31/00 (1995.01), 05/20/1995, Ointment for the treatment of purulent wounds / Pisarenko V.F., Kovalenko A.M., Levitskaya I.L.

4. RU 2521247 C2, A61K 33/08 (2006.01), A61P 31/02 (2006.01), 06/15/2012, Drug for the treatment of digital dermatitis in cattle (Dermatitis digitalis) / Pisarenko V.F., Kovalenko AM, Levitskaya I .L.

5. RU 2655521 C1, A61K 9/06 (2006.01), A61K 31/60 (2006.01), A61K 33/00 (2006.01), A drug for the treatment of digital dermatitis and sole ulcers of cattle / Kovalenko AM, Yavnikov N.V., Dorofeev A.F., Kim V.V.

Claims (2)

The drug for the treatment and prevention of diseases of the skin and skin of an infectious etiology of cattle and small cattle, pigs based on copper chelates in the form of an aerosol spray containing the following components in its composition in the following proportions,%: Copper chelate 20-30 Lentex M4 30-40 Lentex B352R 30-40 Dye 0.01-0.05