RU2698194C2 - Кристаллическая форма 6-[(4r)-4-метил-1,1-диоксидо-1,2,6-тиадиазинан-2-ил]изохинолин-1-карбонитрила - Google Patents
Кристаллическая форма 6-[(4r)-4-метил-1,1-диоксидо-1,2,6-тиадиазинан-2-ил]изохинолин-1-карбонитрила Download PDFInfo
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- RU2698194C2 RU2698194C2 RU2016144671A RU2016144671A RU2698194C2 RU 2698194 C2 RU2698194 C2 RU 2698194C2 RU 2016144671 A RU2016144671 A RU 2016144671A RU 2016144671 A RU2016144671 A RU 2016144671A RU 2698194 C2 RU2698194 C2 RU 2698194C2
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- methyl
- carbonitrile
- isoquinoline
- dioxo
- thiadiazinan
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461993693P | 2014-05-15 | 2014-05-15 | |
| US61/993,693 | 2014-05-15 | ||
| US201562138037P | 2015-03-25 | 2015-03-25 | |
| US62/138,037 | 2015-03-25 | ||
| PCT/IB2015/053194 WO2015173684A1 (en) | 2014-05-15 | 2015-05-01 | Crystalline form of 6-[(4r)-4-methyl-1,2-dioxido-1,2,6-thiadiazinan-2-yl]isoquinoline-1-carbonitrile |
Publications (3)
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| RU2016144671A RU2016144671A (ru) | 2018-06-15 |
| RU2016144671A3 RU2016144671A3 (enExample) | 2018-06-15 |
| RU2698194C2 true RU2698194C2 (ru) | 2019-08-23 |
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| CA2950390C (en) * | 2014-05-30 | 2020-09-22 | Pfizer Inc. | Carbonitrile derivatives as selective androgen receptor modulators |
| WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1194257A3 (ru) * | 1982-05-15 | 1985-11-23 | Пфайзер Корпорейшн (Фирма) | Способ получени хиназолиновых производных или их фармацевтически приемлемых солей |
| WO2005018573A2 (en) * | 2003-08-22 | 2005-03-03 | Ligand Pharmaceuticals Incorporated | 6-cycloamino-2-quinolinone derivatives as androgen receptor modulator compounds |
| WO2009082437A2 (en) * | 2007-12-21 | 2009-07-02 | Ligand Pharmaceuticals Incorporated | Selective androgen receptor modulators (sarms) and uses thereof |
| WO2014087298A1 (en) * | 2012-12-03 | 2014-06-12 | Pfizer Inc. | Novel selective androgen receptor modulators |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0089139A2 (en) | 1982-03-16 | 1983-09-21 | Beecham Group Plc | Antibiotics, their preparation and use |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| GB9518953D0 (en) | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
| WO2000035296A1 (en) | 1996-11-27 | 2000-06-22 | Wm. Wrigley Jr. Company | Improved release of medicament active agents from a chewing gum coating |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| EP1636167A2 (en) | 2003-06-10 | 2006-03-22 | SmithKline Beecham Corporation | 1-aminonaphthalenes as modulators of androgen, glucocorticoid, mineralocorticoid and progesterone receptors |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1194257A3 (ru) * | 1982-05-15 | 1985-11-23 | Пфайзер Корпорейшн (Фирма) | Способ получени хиназолиновых производных или их фармацевтически приемлемых солей |
| WO2005018573A2 (en) * | 2003-08-22 | 2005-03-03 | Ligand Pharmaceuticals Incorporated | 6-cycloamino-2-quinolinone derivatives as androgen receptor modulator compounds |
| WO2009082437A2 (en) * | 2007-12-21 | 2009-07-02 | Ligand Pharmaceuticals Incorporated | Selective androgen receptor modulators (sarms) and uses thereof |
| WO2014087298A1 (en) * | 2012-12-03 | 2014-06-12 | Pfizer Inc. | Novel selective androgen receptor modulators |
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| TWI553007B (zh) | 2016-10-11 |
| RU2016144671A (ru) | 2018-06-15 |
| MX2016014999A (es) | 2017-04-11 |
| JP2015218166A (ja) | 2015-12-07 |
| CY1123826T1 (el) | 2022-05-27 |
| ES2845639T3 (es) | 2021-07-27 |
| EP3143019A1 (en) | 2017-03-22 |
| US9920043B2 (en) | 2018-03-20 |
| TW201546069A (zh) | 2015-12-16 |
| PL3143019T3 (pl) | 2021-03-22 |
| EP3143019B1 (en) | 2020-12-16 |
| PT3143019T (pt) | 2021-01-28 |
| AU2015260906B2 (en) | 2017-08-31 |
| MX371014B (es) | 2020-01-10 |
| ZA201606796B (en) | 2018-04-25 |
| CN106459025A (zh) | 2017-02-22 |
| SI3143019T1 (sl) | 2021-03-31 |
| HUE052692T2 (hu) | 2021-05-28 |
| WO2015173684A1 (en) | 2015-11-19 |
| SG11201608320QA (en) | 2016-11-29 |
| AU2015260906A1 (en) | 2016-10-20 |
| CA2891398A1 (en) | 2015-11-15 |
| DK3143019T3 (da) | 2021-01-04 |
| KR20160144478A (ko) | 2016-12-16 |
| JP6523782B2 (ja) | 2019-06-05 |
| RU2016144671A3 (enExample) | 2018-06-15 |
| CN106459025B (zh) | 2019-05-28 |
| CA2891398C (en) | 2019-09-24 |
| US20170073338A1 (en) | 2017-03-16 |
| IL248918A0 (en) | 2017-01-31 |
| KR101817889B1 (ko) | 2018-01-11 |
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