RU2685706C2 - Фармацевтические композиции, содержащие 15-гэпк, и способы лечения астмы и заболеваний легких с их применением - Google Patents

Фармацевтические композиции, содержащие 15-гэпк, и способы лечения астмы и заболеваний легких с их применением Download PDF

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RU2685706C2
RU2685706C2 RU2016132762A RU2016132762A RU2685706C2 RU 2685706 C2 RU2685706 C2 RU 2685706C2 RU 2016132762 A RU2016132762 A RU 2016132762A RU 2016132762 A RU2016132762 A RU 2016132762A RU 2685706 C2 RU2685706 C2 RU 2685706C2
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RU2016132762A3 (enExample
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Мехар МАНКУ
Джон КЛАЙМАКС
Кевин ДАФФИ
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Эфиммьюн Лимитед
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
RU2016132762A 2014-01-10 2015-01-12 Фармацевтические композиции, содержащие 15-гэпк, и способы лечения астмы и заболеваний легких с их применением RU2685706C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461926052P 2014-01-10 2014-01-10
US61/926,052 2014-01-10
PCT/US2015/011054 WO2015106215A2 (en) 2014-01-10 2015-01-12 Pharmaceutical compositions comprising 15-hepe and methods of treating asthma and lung disorders using same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2019110980A Division RU2019110980A (ru) 2014-01-10 2015-01-12 Фармацевтические композиции, содержащие 15-гэпк, и способы лечения астмы и заболеваний легких с их применением

Publications (3)

Publication Number Publication Date
RU2016132762A RU2016132762A (ru) 2018-02-16
RU2016132762A3 RU2016132762A3 (enExample) 2018-09-20
RU2685706C2 true RU2685706C2 (ru) 2019-04-23

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RU2016132762A RU2685706C2 (ru) 2014-01-10 2015-01-12 Фармацевтические композиции, содержащие 15-гэпк, и способы лечения астмы и заболеваний легких с их применением
RU2019110980A RU2019110980A (ru) 2014-01-10 2015-01-12 Фармацевтические композиции, содержащие 15-гэпк, и способы лечения астмы и заболеваний легких с их применением

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RU2019110980A RU2019110980A (ru) 2014-01-10 2015-01-12 Фармацевтические композиции, содержащие 15-гэпк, и способы лечения астмы и заболеваний легких с их применением

Country Status (15)

Country Link
US (2) US20150196521A1 (enExample)
EP (1) EP3091959A4 (enExample)
JP (2) JP2017505809A (enExample)
KR (1) KR20160132372A (enExample)
CN (1) CN106029051A (enExample)
AU (1) AU2015204531B2 (enExample)
BR (1) BR112016015997A2 (enExample)
CA (1) CA2935986A1 (enExample)
IL (1) IL246623A0 (enExample)
MX (1) MX2016008953A (enExample)
PH (1) PH12016501371A1 (enExample)
RU (2) RU2685706C2 (enExample)
SG (2) SG11201605601UA (enExample)
WO (1) WO2015106215A2 (enExample)
ZA (1) ZA201605492B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013259503B2 (en) 2012-05-10 2017-03-16 Solutex Na Llc Oils with anti-inflammatory activity containing natural specialized proresolving mediators and their precursors
ES2727387T3 (es) 2013-11-15 2019-10-15 Ds Biopharma Ltd Sal de lisina de ácido 15-hidroxi-8(Z),11(Z),13(E)-eicosatrienoico
CN107405324A (zh) * 2015-01-16 2017-11-28 艾菲穆恩有限公司 包含15‑hepe的组合物和其使用方法
CN112245420A (zh) * 2015-07-21 2021-01-22 艾菲穆恩有限公司 用于治疗或预防癌症和神经疾病的包括15-hepe的组合物
WO2017041094A1 (en) 2015-09-03 2017-03-09 Solutex Na Llc Compositions comprising omega-3 fatty acids, 17-hdha and 18- hepe and methods of using same
AU2016370626B2 (en) * 2015-12-18 2020-08-20 Afimmune Limited Compositions comprising 15-HEPE and methods of using the same
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases
CN111481550A (zh) * 2020-05-14 2020-08-04 王兆霖 含有噻托溴铵和阿福特罗的药物制剂

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055538A1 (en) * 2000-02-16 2002-05-09 Serhan Charles N. Aspirin-triggered lipid mediators
WO2003063793A2 (en) * 2002-01-31 2003-08-07 Pilot Therapeutics, Inc. Fatty acid-containing compositions and methods for the treatment of cytokine mediated disorders
WO2012135032A2 (en) * 2011-03-25 2012-10-04 The Brigham And Women's Hospital, Inc. Anti-inflammatory particles
US20120264705A1 (en) * 2012-01-26 2012-10-18 Dignity Sciences Limited Antimicrobial compositions comprising 15-hetre and methods of use thereof

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JPH05186342A (ja) * 1992-01-10 1993-07-27 Fujirebio Inc 免疫調節作用を併せもつ抗炎症剤
US20060160095A1 (en) * 2002-12-13 2006-07-20 Eirx Therapeutics Limited Survivin
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
SI1863476T1 (sl) * 2005-03-16 2016-05-31 Meda Pharma Gmbh & Co. Kg Kombinacija antiholinergikov in antagonistov receptorja levkotriena za zdravljenje respiratornih bolezni
EP2607358A4 (en) * 2010-08-19 2014-01-29 Univ Tokyo NEW OMEGA-3 FATTY ACIDS RECOVERY-RESISTANT METABOLITE
US8293790B2 (en) * 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
US20130267598A1 (en) * 2012-02-23 2013-10-10 Dignity Sciences Limited Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15-hetre and methods of reducing sebum production using same
AU2013259503B2 (en) * 2012-05-10 2017-03-16 Solutex Na Llc Oils with anti-inflammatory activity containing natural specialized proresolving mediators and their precursors
GB201301626D0 (en) * 2013-01-30 2013-03-13 Dignity Sciences Ltd Composition comprising 15-OHEPA and methods of using the same
MA41120A (fr) * 2014-12-02 2017-10-10 Afimmune Ltd Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055538A1 (en) * 2000-02-16 2002-05-09 Serhan Charles N. Aspirin-triggered lipid mediators
WO2003063793A2 (en) * 2002-01-31 2003-08-07 Pilot Therapeutics, Inc. Fatty acid-containing compositions and methods for the treatment of cytokine mediated disorders
WO2012135032A2 (en) * 2011-03-25 2012-10-04 The Brigham And Women's Hospital, Inc. Anti-inflammatory particles
US20120264705A1 (en) * 2012-01-26 2012-10-18 Dignity Sciences Limited Antimicrobial compositions comprising 15-hetre and methods of use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
WHEELOCK A.M. et al. American Journal of Respiratory and Critical Care Medicine // Allergic asthmatics exhibit altered response in oxylipin profile as compared to healthy and asthmatic controls after allergen provocation, 2011, 183:1, . *
WHEELOCK A.M. et al. American Journal of Respiratory and Critical Care Medicine // Allergic asthmatics exhibit altered response in oxylipin profile as compared to healthy and asthmatic controls after allergen provocation, 2011, 183:1, реферат. *

Also Published As

Publication number Publication date
AU2015204531A1 (en) 2016-08-18
EP3091959A2 (en) 2016-11-16
WO2015106215A2 (en) 2015-07-16
IL246623A0 (en) 2016-08-31
JP2017505809A (ja) 2017-02-23
US20150196521A1 (en) 2015-07-16
CA2935986A1 (en) 2015-07-16
AU2015204531B2 (en) 2019-11-14
PH12016501371A1 (en) 2016-08-15
BR112016015997A2 (pt) 2018-03-27
EP3091959A4 (en) 2017-09-20
RU2019110980A (ru) 2019-08-26
WO2015106215A3 (en) 2016-02-18
SG11201605601UA (en) 2016-08-30
RU2016132762A (ru) 2018-02-16
JP2020002150A (ja) 2020-01-09
MX2016008953A (es) 2017-02-02
KR20160132372A (ko) 2016-11-18
CN106029051A (zh) 2016-10-12
SG10202000496XA (en) 2020-03-30
US20160324820A1 (en) 2016-11-10
ZA201605492B (en) 2018-11-28
RU2016132762A3 (enExample) 2018-09-20

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Effective date: 20210113