RU2663687C2 - Композиции наночастиц альбумина и паклитаксела - Google Patents

Композиции наночастиц альбумина и паклитаксела Download PDF

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Publication number
RU2663687C2
RU2663687C2 RU2015131141A RU2015131141A RU2663687C2 RU 2663687 C2 RU2663687 C2 RU 2663687C2 RU 2015131141 A RU2015131141 A RU 2015131141A RU 2015131141 A RU2015131141 A RU 2015131141A RU 2663687 C2 RU2663687 C2 RU 2663687C2
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Russia
Prior art keywords
albumin
composition
pharmaceutical composition
paclitaxel
nanoparticles
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RU2015131141A
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English (en)
Russian (ru)
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RU2015131141A (ru
Inventor
Нейл П. ДИСЭЙ
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АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
RU2015131141A 2012-12-28 2013-12-19 Композиции наночастиц альбумина и паклитаксела RU2663687C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261747123P 2012-12-28 2012-12-28
US61/747,123 2012-12-28
US13/794,705 US20140186447A1 (en) 2012-12-28 2013-03-11 Nanoparticle compositions of albumin and paclitaxel
US13/794,705 2013-03-11
PCT/US2013/076630 WO2014105644A1 (en) 2012-12-28 2013-12-19 Nanoparticle compositions of albumin and paclitaxel

Publications (2)

Publication Number Publication Date
RU2015131141A RU2015131141A (ru) 2017-02-03
RU2663687C2 true RU2663687C2 (ru) 2018-08-08

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RU2015131141A RU2663687C2 (ru) 2012-12-28 2013-12-19 Композиции наночастиц альбумина и паклитаксела

Country Status (19)

Country Link
US (2) US20140186447A1 (OSRAM)
EP (1) EP2938340A4 (OSRAM)
JP (2) JP2016504362A (OSRAM)
KR (1) KR20150100903A (OSRAM)
CN (1) CN105007912A (OSRAM)
AU (1) AU2013370955B2 (OSRAM)
BR (1) BR112015015319A2 (OSRAM)
CA (1) CA2896288A1 (OSRAM)
CR (1) CR20150386A (OSRAM)
HK (1) HK1216611A1 (OSRAM)
IL (1) IL239593A0 (OSRAM)
MX (1) MX2015008361A (OSRAM)
NI (1) NI201500090A (OSRAM)
NZ (1) NZ630912A (OSRAM)
PH (1) PH12015501486B1 (OSRAM)
RU (1) RU2663687C2 (OSRAM)
SG (1) SG11201505111TA (OSRAM)
WO (1) WO2014105644A1 (OSRAM)
ZA (1) ZA201504762B (OSRAM)

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Also Published As

Publication number Publication date
CA2896288A1 (en) 2014-07-03
SG11201505111TA (en) 2015-07-30
RU2015131141A (ru) 2017-02-03
HK1216611A1 (zh) 2016-11-25
EP2938340A4 (en) 2016-08-03
KR20150100903A (ko) 2015-09-02
JP2016504362A (ja) 2016-02-12
EP2938340A1 (en) 2015-11-04
AU2013370955A1 (en) 2015-07-16
CN105007912A (zh) 2015-10-28
WO2014105644A1 (en) 2014-07-03
NI201500090A (es) 2015-12-22
IL239593A0 (en) 2015-08-31
US20140186447A1 (en) 2014-07-03
AU2013370955B2 (en) 2018-12-06
PH12015501486A1 (en) 2015-09-21
NZ630912A (en) 2017-05-26
BR112015015319A2 (pt) 2017-07-11
JP2018087241A (ja) 2018-06-07
MX2015008361A (es) 2016-03-11
PH12015501486B1 (en) 2020-12-16
US20190192477A1 (en) 2019-06-27
ZA201504762B (en) 2016-10-26
CR20150386A (es) 2015-10-07

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