RU2622021C2 - Лечение кахексии - Google Patents

Лечение кахексии Download PDF

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Publication number
RU2622021C2
RU2622021C2 RU2014111662A RU2014111662A RU2622021C2 RU 2622021 C2 RU2622021 C2 RU 2622021C2 RU 2014111662 A RU2014111662 A RU 2014111662A RU 2014111662 A RU2014111662 A RU 2014111662A RU 2622021 C2 RU2622021 C2 RU 2622021C2
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RU
Russia
Prior art keywords
subject
patients
cachexia
mab
human
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RU2014111662A
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English (en)
Russian (ru)
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RU2014111662A (ru
Inventor
Джон СИМАРД
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ИксБиотеч, Инк.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2014111662A 2011-09-23 2012-09-21 Лечение кахексии RU2622021C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161538309P 2011-09-23 2011-09-23
US61/538,309 2011-09-23
PCT/US2012/056492 WO2013043973A2 (en) 2011-09-23 2012-09-21 Cachexia treatment

Publications (2)

Publication Number Publication Date
RU2014111662A RU2014111662A (ru) 2015-10-27
RU2622021C2 true RU2622021C2 (ru) 2017-06-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014111662A RU2622021C2 (ru) 2011-09-23 2012-09-21 Лечение кахексии

Country Status (16)

Country Link
US (2) US9809649B2 (https=)
EP (1) EP2750709B1 (https=)
JP (1) JP6204915B2 (https=)
KR (1) KR102039198B1 (https=)
CN (2) CN108404127B (https=)
AU (1) AU2012312225B2 (https=)
CA (1) CA2849710C (https=)
DK (1) DK2750709T3 (https=)
ES (1) ES2695102T3 (https=)
IL (1) IL231622B (https=)
MX (1) MX356808B (https=)
PH (1) PH12014500645A1 (https=)
PT (1) PT2750709T (https=)
RU (1) RU2622021C2 (https=)
WO (1) WO2013043973A2 (https=)
ZA (1) ZA201402057B (https=)

Cited By (1)

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RU2843348C2 (ru) * 2021-06-30 2025-07-14 ШАНХАЙ ДжейЭмТи-БАЙО ТЕКНОЛОДЖИ КО., ЛТД. Антитело к GFRAL и его применение

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US9724409B2 (en) 2011-04-01 2017-08-08 Xbiotech, Inc. Treatment of inflammatory skin disease
CN108404127B (zh) 2011-09-23 2025-12-12 埃克斯生物科技公司 恶病质治疗
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US10975146B2 (en) 2018-06-29 2021-04-13 Cedars-Sinai Medical Center Interleukin-1 inhibition for combination treatment of pancreatic cancer
CA3095740A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin alpha (il-1a)
CA3095679A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleuken 1 alpha (il-1a)
CA3095676A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin 1 alpha (il-1a)
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2843348C2 (ru) * 2021-06-30 2025-07-14 ШАНХАЙ ДжейЭмТи-БАЙО ТЕКНОЛОДЖИ КО., ЛТД. Антитело к GFRAL и его применение

Also Published As

Publication number Publication date
KR20140078690A (ko) 2014-06-25
MX2014003402A (es) 2015-03-05
ES2695102T3 (es) 2019-01-02
EP2750709B1 (en) 2018-08-15
WO2013043973A2 (en) 2013-03-28
ZA201402057B (en) 2016-08-31
IL231622B (en) 2018-10-31
CN108404127A (zh) 2018-08-17
CN108404127B (zh) 2025-12-12
JP6204915B2 (ja) 2017-09-27
US20180037647A1 (en) 2018-02-08
EP2750709A2 (en) 2014-07-09
CN103906536A (zh) 2014-07-02
PH12014500645A1 (en) 2014-05-05
CA2849710C (en) 2020-04-28
AU2012312225A1 (en) 2014-04-10
US20130078258A1 (en) 2013-03-28
EP2750709A4 (en) 2015-06-10
JP2014526559A (ja) 2014-10-06
KR102039198B1 (ko) 2019-10-31
US9809649B2 (en) 2017-11-07
RU2014111662A (ru) 2015-10-27
DK2750709T3 (en) 2018-12-03
MX356808B (es) 2018-06-14
HK1199616A1 (en) 2015-07-10
US10202449B2 (en) 2019-02-12
PT2750709T (pt) 2018-11-22
AU2012312225B2 (en) 2017-10-05
IL231622A0 (en) 2014-05-28
CA2849710A1 (en) 2013-03-28

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