RU2622021C2 - Лечение кахексии - Google Patents

Лечение кахексии Download PDF

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Publication number
RU2622021C2
RU2622021C2 RU2014111662A RU2014111662A RU2622021C2 RU 2622021 C2 RU2622021 C2 RU 2622021C2 RU 2014111662 A RU2014111662 A RU 2014111662A RU 2014111662 A RU2014111662 A RU 2014111662A RU 2622021 C2 RU2622021 C2 RU 2622021C2
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RU
Russia
Prior art keywords
subject
patients
cachexia
mab
human
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RU2014111662A
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English (en)
Russian (ru)
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RU2014111662A (ru
Inventor
Джон СИМАРД
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ИксБиотеч, Инк.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2014111662A 2011-09-23 2012-09-21 Лечение кахексии RU2622021C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161538309P 2011-09-23 2011-09-23
US61/538,309 2011-09-23
PCT/US2012/056492 WO2013043973A2 (en) 2011-09-23 2012-09-21 Cachexia treatment

Publications (2)

Publication Number Publication Date
RU2014111662A RU2014111662A (ru) 2015-10-27
RU2622021C2 true RU2622021C2 (ru) 2017-06-08

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014111662A RU2622021C2 (ru) 2011-09-23 2012-09-21 Лечение кахексии

Country Status (16)

Country Link
US (2) US9809649B2 (enExample)
EP (1) EP2750709B1 (enExample)
JP (1) JP6204915B2 (enExample)
KR (1) KR102039198B1 (enExample)
CN (2) CN108404127B (enExample)
AU (1) AU2012312225B2 (enExample)
CA (1) CA2849710C (enExample)
DK (1) DK2750709T3 (enExample)
ES (1) ES2695102T3 (enExample)
IL (1) IL231622B (enExample)
MX (1) MX356808B (enExample)
PH (1) PH12014500645A1 (enExample)
PT (1) PT2750709T (enExample)
RU (1) RU2622021C2 (enExample)
WO (1) WO2013043973A2 (enExample)
ZA (1) ZA201402057B (enExample)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
RU2843348C2 (ru) * 2021-06-30 2025-07-14 ШАНХАЙ ДжейЭмТи-БАЙО ТЕКНОЛОДЖИ КО., ЛТД. Антитело к GFRAL и его применение

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US9545441B2 (en) 2012-09-18 2017-01-17 Xbiotech, Inc. Treatment of diabetes
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JP7145162B2 (ja) 2017-02-16 2022-09-30 ヤンセン バイオテク，インコーポレイテッド 化膿性汗腺炎の処置
US10975146B2 (en) 2018-06-29 2021-04-13 Cedars-Sinai Medical Center Interleukin-1 inhibition for combination treatment of pancreatic cancer
CA3095740A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin alpha (il-1a)
CA3095675A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin 1 alpha (il-1a)
CA3095679A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleuken 1 alpha (il-1a)
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2843348C2 (ru) * 2021-06-30 2025-07-14 ШАНХАЙ ДжейЭмТи-БАЙО ТЕКНОЛОДЖИ КО., ЛТД. Антитело к GFRAL и его применение

Also Published As

Publication number Publication date
US20180037647A1 (en) 2018-02-08
ZA201402057B (en) 2016-08-31
EP2750709B1 (en) 2018-08-15
WO2013043973A2 (en) 2013-03-28
PH12014500645A1 (en) 2014-05-05
CA2849710C (en) 2020-04-28
JP2014526559A (ja) 2014-10-06
HK1199616A1 (en) 2015-07-10
KR102039198B1 (ko) 2019-10-31
CN108404127A (zh) 2018-08-17
US10202449B2 (en) 2019-02-12
PT2750709T (pt) 2018-11-22
CA2849710A1 (en) 2013-03-28
US9809649B2 (en) 2017-11-07
US20130078258A1 (en) 2013-03-28
ES2695102T3 (es) 2019-01-02
JP6204915B2 (ja) 2017-09-27
RU2014111662A (ru) 2015-10-27
AU2012312225A1 (en) 2014-04-10
DK2750709T3 (en) 2018-12-03
IL231622B (en) 2018-10-31
CN103906536A (zh) 2014-07-02
MX356808B (es) 2018-06-14
AU2012312225B2 (en) 2017-10-05
EP2750709A4 (en) 2015-06-10
CN108404127B (zh) 2025-12-12
KR20140078690A (ko) 2014-06-25
IL231622A0 (en) 2014-05-28
MX2014003402A (es) 2015-03-05
EP2750709A2 (en) 2014-07-09

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