RU2619184C2 - Антисмысловые нуклеиновые кислоты - Google Patents

Антисмысловые нуклеиновые кислоты Download PDF

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RU2619184C2
RU2619184C2 RU2014130600A RU2014130600A RU2619184C2 RU 2619184 C2 RU2619184 C2 RU 2619184C2 RU 2014130600 A RU2014130600 A RU 2014130600A RU 2014130600 A RU2014130600 A RU 2014130600A RU 2619184 C2 RU2619184 C2 RU 2619184C2
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exon
seq
pmo
nucleotides
nucleic acid
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RU2014130600A (ru
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Наоки ВАТАНАБЕ
Харуна СЕО
Син'ити ТАКЕДА
Тецуя НАГАТА
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Ниппон Синяку Ко., Лтд.
Нэшнл Сентер Оф Ньюролоджи Энд Сайкайэтри
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    • A—HUMAN NECESSITIES
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    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
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    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/323—Chemical structure of the sugar modified ring structure
    • C12N2310/3233—Morpholino-type ring
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    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications
    • C12N2320/33—Alteration of splicing

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2014130600A 2011-12-28 2012-12-27 Антисмысловые нуклеиновые кислоты RU2619184C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2011288040 2011-12-28
JP2011-288040 2011-12-28
JP2012043092 2012-02-29
JP2012-043092 2012-02-29
PCT/JP2012/084295 WO2013100190A1 (ja) 2011-12-28 2012-12-27 アンチセンス核酸

Related Child Applications (1)

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RU2017114509A Division RU2651468C1 (ru) 2011-12-28 2012-12-27 Антисмысловые нуклеиновые кислоты

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RU2014130600A RU2014130600A (ru) 2016-02-20
RU2619184C2 true RU2619184C2 (ru) 2017-05-12

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RU2014130600A RU2619184C2 (ru) 2011-12-28 2012-12-27 Антисмысловые нуклеиновые кислоты
RU2017114509A RU2651468C1 (ru) 2011-12-28 2012-12-27 Антисмысловые нуклеиновые кислоты
RU2018109906A RU2681470C1 (ru) 2011-12-28 2018-03-21 Антисмысловые нуклеиновые кислоты

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RU2018109906A RU2681470C1 (ru) 2011-12-28 2018-03-21 Антисмысловые нуклеиновые кислоты

Country Status (12)

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US (5) US9512424B2 (https=)
EP (2) EP2799548B1 (https=)
JP (6) JP6141770B2 (https=)
KR (2) KR102240139B1 (https=)
CN (10) CN117721110A (https=)
AU (2) AU2012360702C1 (https=)
CA (2) CA2861247C (https=)
ES (1) ES2748868T3 (https=)
IN (1) IN2014DN06220A (https=)
RU (3) RU2619184C2 (https=)
TW (1) TWI606059B (https=)
WO (1) WO2013100190A1 (https=)

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