RU2613422C2 - Антитело к blys - Google Patents
Антитело к blys Download PDFInfo
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- RU2613422C2 RU2613422C2 RU2014133410A RU2014133410A RU2613422C2 RU 2613422 C2 RU2613422 C2 RU 2613422C2 RU 2014133410 A RU2014133410 A RU 2014133410A RU 2014133410 A RU2014133410 A RU 2014133410A RU 2613422 C2 RU2613422 C2 RU 2613422C2
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- blys
- amino acid
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210160474.3A CN103421113B (zh) | 2012-05-22 | 2012-05-22 | 抗BLyS抗体 |
| CN201210160474.3 | 2012-05-22 | ||
| PCT/CN2013/076074 WO2013174264A1 (zh) | 2012-05-22 | 2013-05-22 | 抗BLyS抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2014133410A RU2014133410A (ru) | 2016-07-10 |
| RU2613422C2 true RU2613422C2 (ru) | 2017-03-16 |
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| RU2014133410A RU2613422C2 (ru) | 2012-05-22 | 2013-05-22 | Антитело к blys |
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| WO (1) | WO2013174264A1 (enExample) |
| ZA (1) | ZA201408955B (enExample) |
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|---|---|---|---|---|
| GB0615672D0 (en) | 2006-08-07 | 2006-09-13 | Rencol Tolerance Rings Ltd | Assembly of a shaft and a housing assembly |
| KR101935088B1 (ko) | 2012-08-24 | 2019-01-04 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | Ror1 암을 치료하고 전이를 저해하는데 이용을 위한 항체와 백신 |
| CN104045713B (zh) * | 2013-03-13 | 2019-02-12 | 江苏诺迈博生物医药科技有限公司 | 一种抗Blys的单克隆抗体及含有该抗体的药物组合物 |
| CN104804090B (zh) * | 2014-01-29 | 2018-03-27 | 普瑞金（深圳）生物技术有限公司 | 一种抗b细胞生长刺激因子的纳米抗体和用途 |
| CN104804092B (zh) * | 2014-01-29 | 2018-03-27 | 天津胜发生物技术有限公司 | 一种抗b细胞生长刺激因子的纳米抗体及其用途 |
| CN104804091B (zh) * | 2014-01-29 | 2018-03-27 | 普瑞金（深圳）生物技术有限公司 | 一种抗b细胞生长刺激因子的纳米抗体及用途 |
| EP3151857A4 (en) * | 2014-06-03 | 2018-04-18 | Merck Sharp & Dohme Corp. | Anti-blys antibodies |
| CN104628856A (zh) * | 2015-01-23 | 2015-05-20 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 一种抗BLyS单链抗体及其制备方法和用途 |
| CN105061596B (zh) * | 2015-08-05 | 2019-01-29 | 江苏诺迈博生物医药科技有限公司 | 人b淋巴细胞刺激因子的单克隆抗体及其应用 |
| CN106916224B (zh) * | 2015-12-28 | 2021-03-23 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 抗b淋巴细胞刺激因子单克隆抗体及其制备方法和用途 |
| IL299099B2 (en) | 2016-06-27 | 2025-07-01 | Univ California | Cancer treatment combinations |
| US20210347873A1 (en) * | 2016-07-06 | 2021-11-11 | Shanghai Pharmaexplorer Co., Ltd. | Blys antibody, preparation method therefor and application thereof |
| WO2018157169A1 (en) * | 2017-02-27 | 2018-08-30 | Caerus Therapeutics, Inc. | Antibody constructs and methods of treating cancer |
| US12404346B2 (en) | 2019-01-31 | 2025-09-02 | Siemens Healthcare Diagnostics Inc. | Anti-naloxone and anti-naltrexone monoclonal antibodies and methods of production and use thereof |
| CN112111461B (zh) * | 2020-08-17 | 2022-08-30 | 浙江正熙生物医药有限公司 | 一种单细胞分选构建单克隆抗体高产株细胞工作库的方法 |
| WO2022223028A1 (zh) * | 2021-04-23 | 2022-10-27 | 上海君实生物医药科技股份有限公司 | 抗BLyS抗体、其药物组合物及其用途 |
| US20240182599A1 (en) * | 2022-10-07 | 2024-06-06 | Abwiz Bio, Inc. | Anti-ige antibodies |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002002641A1 (en) * | 2000-06-16 | 2002-01-10 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to blys |
| RU2005141541A (ru) * | 2003-06-05 | 2006-06-27 | Дженентек, Инк. (Us) | Комбинированная терапия в-клеточных нарушений |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2266439C (en) * | 1996-10-25 | 2009-06-16 | Human Genome Sciences, Inc. | Neutrokine .alpha. |
| US6812327B1 (en) * | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
| US7879328B2 (en) | 2000-06-16 | 2011-02-01 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator |
| AU2002364954A1 (en) | 2001-11-16 | 2003-07-15 | Human Genome Sciences, Inc. | ANTIBODIES THAT IMMUNOSPECIFICALLY BIND TO BLyS |
| US20020150579A1 (en) * | 2002-01-10 | 2002-10-17 | Kimberly Robert P. | B lymphocyte stimulator (BLyS) as a marker in management of systemic lupus erythematosus |
| CN1168831C (zh) * | 2002-05-24 | 2004-09-29 | 张志方 | 一种重组人b淋巴细胞刺激因子表达载体的构建、dna免疫制备单克隆抗体及其应用 |
| AU2004285455A1 (en) | 2003-10-20 | 2005-05-12 | Biogen Idec Ma Inc. | Therapeutic regimens for BAFF antagonists |
| CN101851291B (zh) * | 2010-02-09 | 2011-10-26 | 中国人民解放军第四军医大学 | 一种抗人baff单克隆抗体的重链和轻链可变区 |
-
2012
- 2012-05-22 CN CN201210160474.3A patent/CN103421113B/zh active Active
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2013
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2014
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002002641A1 (en) * | 2000-06-16 | 2002-01-10 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to blys |
| RU2005141541A (ru) * | 2003-06-05 | 2006-06-27 | Дженентек, Инк. (Us) | Комбинированная терапия в-клеточных нарушений |
Non-Patent Citations (1)
| Title |
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| MOORE P.A. et al., BLyS: Member of the Tumor Necrosis Factor Family and B Lymphocyte Stimulator, SCIENCE, 1999, vol.285, pp.260-263. SHU H.B. et al.,TALL-1 is a novel member of the TNF family that is down-regulated by mitogens, Journal of Leukocyte Biology, 1999, vol.65 no.5, pp.680-683. * |
Also Published As
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| IN2014MN02367A (enExample) | 2015-08-14 |
| CN103421113B (zh) | 2018-01-19 |
| EP2853543A1 (en) | 2015-04-01 |
| CN103421113A (zh) | 2013-12-04 |
| JP6006404B2 (ja) | 2016-10-12 |
| BR112014025651A2 (pt) | 2017-07-04 |
| EP3792280A2 (en) | 2021-03-17 |
| US20150259409A1 (en) | 2015-09-17 |
| JP2015517505A (ja) | 2015-06-22 |
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| RU2014133410A (ru) | 2016-07-10 |
| EP2853543A4 (en) | 2016-03-30 |
| ZA201408955B (en) | 2015-12-23 |
| EP2853543B1 (en) | 2020-09-02 |
| US9828423B2 (en) | 2017-11-28 |
| WO2013174264A1 (zh) | 2013-11-28 |
| EP2853543A8 (en) | 2015-05-13 |
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