RU2602739C2 - Производное пиразола и его применение в медицинских целях - Google Patents

Производное пиразола и его применение в медицинских целях Download PDF

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Publication number
RU2602739C2
RU2602739C2 RU2014149181/15A RU2014149181A RU2602739C2 RU 2602739 C2 RU2602739 C2 RU 2602739C2 RU 2014149181/15 A RU2014149181/15 A RU 2014149181/15A RU 2014149181 A RU2014149181 A RU 2014149181A RU 2602739 C2 RU2602739 C2 RU 2602739C2
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constipation
group
compound
administration
administered
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RU2014149181/15A
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Russian (ru)
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RU2014149181A (ru
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Масаюки ИЗАДЗИ
Масааки ТАКЕМУРА
Хидетоси ИСАВА
Юкихико ХОТЕИ
Итару МИЯСИТА
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Киссеи Фармасьютикал Ко., Лтд.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2014149181/15A 2012-05-07 2013-05-02 Производное пиразола и его применение в медицинских целях RU2602739C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012-105847 2012-05-07
JP2012105847 2012-05-07
PCT/JP2013/062755 WO2013168671A1 (ja) 2012-05-07 2013-05-02 ピラゾール誘導体及びその医薬用途

Publications (2)

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RU2014149181A RU2014149181A (ru) 2016-06-27
RU2602739C2 true RU2602739C2 (ru) 2016-11-20

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RU2014149181/15A RU2602739C2 (ru) 2012-05-07 2013-05-02 Производное пиразола и его применение в медицинских целях

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US (2) US9273085B2 (cg-RX-API-DMAC7.html)
EP (1) EP2848254B1 (cg-RX-API-DMAC7.html)
JP (2) JP5663699B2 (cg-RX-API-DMAC7.html)
KR (1) KR101868991B1 (cg-RX-API-DMAC7.html)
CN (1) CN104284665B (cg-RX-API-DMAC7.html)
AU (1) AU2013258566B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014027841B1 (cg-RX-API-DMAC7.html)
CA (1) CA2872002C (cg-RX-API-DMAC7.html)
DK (1) DK2848254T3 (cg-RX-API-DMAC7.html)
ES (1) ES2601127T3 (cg-RX-API-DMAC7.html)
MX (1) MX359988B (cg-RX-API-DMAC7.html)
PL (1) PL2848254T3 (cg-RX-API-DMAC7.html)
PT (1) PT2848254T (cg-RX-API-DMAC7.html)
RU (1) RU2602739C2 (cg-RX-API-DMAC7.html)
WO (1) WO2013168671A1 (cg-RX-API-DMAC7.html)

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CA2899834C (en) 2013-02-04 2020-09-01 Taisho Pharmaceutical Co., Ltd. Use of 4-isopropylphenyl glucitol compounds in the treatment of constipation
JP6751020B2 (ja) 2014-06-25 2020-09-02 Ｅａファーマ株式会社 固形製剤及びその着色防止又は着色低減方法
CN106573033A (zh) * 2014-06-25 2017-04-19 Ea制药株式会社 固体制剂及其稳定化方法
US11596644B2 (en) 2018-03-28 2023-03-07 Avolynt Method for treating post-prandial hypoglycemia
TW202015699A (zh) 2018-06-05 2020-05-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽汁酸調節劑之用途
US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
FI3810581T3 (fi) 2018-06-20 2025-02-28 Albireo Ab Odeviksibaatin kiteiset modifikaatiot
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
US10975045B2 (en) 2019-02-06 2021-04-13 Aibireo AB Benzothiazepine compounds and their use as bile acid modulators
US10941127B2 (en) 2019-02-06 2021-03-09 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
ES2937153T3 (es) 2019-02-06 2023-03-24 Albireo Ab Compuestos de benzotiadiazepinas y su uso como moduladores de ácidos biliares
US11014898B1 (en) 2020-12-04 2021-05-25 Albireo Ab Benzothiazepine compounds and their use as bile acid modulators
CN114761018B (zh) 2019-12-04 2025-12-02 阿尔比里奥公司 苯并硫杂二氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途
KR20220109450A (ko) 2019-12-04 2022-08-04 알비레오 에이비 벤조티아(디)아제핀 화합물 및 담즙산 조절제로서의 이의 용도
ES2973355T3 (es) 2019-12-04 2024-06-19 Albireo Ab Compuestos de benzotia(di)azepina y su uso como moduladores del ácido biliar
CA3158276A1 (en) 2019-12-04 2021-06-10 Per-Goran Gillberg Benzothia(di)azepine compounds and their use as bile acid modulators
CA3186857A1 (en) 2020-08-03 2022-02-10 Per-Goran Gillberg Benzothia(di)azepine compounds and their use as bile acid modulators
JP2023549226A (ja) 2020-11-12 2023-11-22 アルビレオ エービー 進行性家族性肝内胆汁うっ滞症（ｐｆｉｃ）を処置するためのオデビキシバット
CN116583504A (zh) 2020-12-04 2023-08-11 阿尔比里奥公司 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途
TW202313579A (zh) 2021-06-03 2023-04-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途

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WO2009084531A1 (ja) * 2007-12-27 2009-07-09 Kissei Pharmaceutical Co., Ltd. ピラゾール誘導体のモノセバシン酸塩
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RU2437888C2 (ru) * 2006-04-26 2011-12-27 Дженентек, Инк. Ингибиторы фосфоинозитид-3-киназы и содержащие их фармацевтические композиции

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WO2009084531A1 (ja) * 2007-12-27 2009-07-09 Kissei Pharmaceutical Co., Ltd. ピラゾール誘導体のモノセバシン酸塩
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US9694027B2 (en) 2017-07-04
PT2848254T (pt) 2016-10-05
KR101868991B1 (ko) 2018-06-19
DK2848254T3 (en) 2016-10-31
EP2848254A4 (en) 2015-07-15
CN104284665B (zh) 2016-11-16
MX359988B (es) 2018-10-18
US20150141631A1 (en) 2015-05-21
CN104284665A (zh) 2015-01-14
BR112014027841A8 (pt) 2021-09-28
RU2014149181A (ru) 2016-06-27
AU2013258566B2 (en) 2017-03-16
JP6105546B2 (ja) 2017-03-29
WO2013168671A1 (ja) 2013-11-14
JPWO2013168671A1 (ja) 2016-01-07
PL2848254T3 (pl) 2017-03-31
US20160129031A1 (en) 2016-05-12
ES2601127T3 (es) 2017-02-14
KR20150013671A (ko) 2015-02-05
MX2014013696A (es) 2015-02-05
US9273085B2 (en) 2016-03-01
JP2015083580A (ja) 2015-04-30
EP2848254A1 (en) 2015-03-18
CA2872002A1 (en) 2013-11-14
AU2013258566A1 (en) 2014-11-27
EP2848254B1 (en) 2016-08-03
BR112014027841A2 (pt) 2017-06-27
HK1204773A1 (en) 2015-12-04
CA2872002C (en) 2019-01-15
BR112014027841B1 (pt) 2022-08-09
JP5663699B2 (ja) 2015-02-04

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