RU2591804C2 - Композиции бендамустина и циклополисахарида - Google Patents

Композиции бендамустина и циклополисахарида Download PDF

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Publication number
RU2591804C2
RU2591804C2 RU2011138844/15A RU2011138844A RU2591804C2 RU 2591804 C2 RU2591804 C2 RU 2591804C2 RU 2011138844/15 A RU2011138844/15 A RU 2011138844/15A RU 2011138844 A RU2011138844 A RU 2011138844A RU 2591804 C2 RU2591804 C2 RU 2591804C2
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RU
Russia
Prior art keywords
bendamustine
composition
sbecd
solution
cyclodextrin
Prior art date
Application number
RU2011138844/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2011138844A (ru
Inventor
Попек Томаз
Пател Кишоре
Алахов Валерий
Пиетрзински Грзегорз
Original Assignee
Супратек Фарма, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42631521&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2591804(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Супратек Фарма, Инк. filed Critical Супратек Фарма, Инк.
Publication of RU2011138844A publication Critical patent/RU2011138844A/ru
Application granted granted Critical
Publication of RU2591804C2 publication Critical patent/RU2591804C2/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2011138844/15A 2009-02-25 2010-02-24 Композиции бендамустина и циклополисахарида RU2591804C2 (ru)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US20854109P 2009-02-25 2009-02-25
US61/208,541 2009-02-25
US26994409P 2009-07-01 2009-07-01
US61/269,944 2009-07-01
US27136409P 2009-07-20 2009-07-20
US61/271,364 2009-07-20
US27929309P 2009-10-19 2009-10-19
US61/279,293 2009-10-19
PCT/IB2010/000502 WO2010097700A1 (en) 2009-02-25 2010-02-24 Bendamustine cyclopolysaccharide compositions
US12/711,979 US8436032B2 (en) 2009-02-25 2010-02-24 Bendamustine cyclopolysaccharide compositions
US12/711,979 2010-02-24

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2016124871A Division RU2734236C2 (ru) 2009-02-25 2010-02-24 Композиции бендамустина и циклополисахарида

Publications (2)

Publication Number Publication Date
RU2011138844A RU2011138844A (ru) 2013-04-10
RU2591804C2 true RU2591804C2 (ru) 2016-07-20

Family

ID=42631521

Family Applications (2)

Application Number Title Priority Date Filing Date
RU2016124871A RU2734236C2 (ru) 2009-02-25 2010-02-24 Композиции бендамустина и циклополисахарида
RU2011138844/15A RU2591804C2 (ru) 2009-02-25 2010-02-24 Композиции бендамустина и циклополисахарида

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RU2016124871A RU2734236C2 (ru) 2009-02-25 2010-02-24 Композиции бендамустина и циклополисахарида

Country Status (12)

Country Link
US (2) US8436032B2 (enExample)
EP (2) EP2792369B1 (enExample)
JP (1) JP5654498B2 (enExample)
KR (1) KR101798951B1 (enExample)
CN (2) CN102935080A (enExample)
AU (1) AU2010217297A1 (enExample)
CA (1) CA2753641C (enExample)
ES (2) ES2525257T3 (enExample)
HU (1) HUE038234T2 (enExample)
NO (1) NO2792369T3 (enExample)
RU (2) RU2734236C2 (enExample)
WO (1) WO2010097700A1 (enExample)

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AU2010217297A1 (en) 2009-02-25 2011-10-20 Supratek Pharma, Inc. Bendamustine cyclopolysaccharide compositions
RS62327B1 (sr) 2010-01-28 2021-10-29 Eagle Pharmaceuticals Inc Formulacije bendamustina
WO2011103150A2 (en) * 2010-02-18 2011-08-25 Cephalon, Inc. Lyophilized preparations of bendamustine
US20110207764A1 (en) * 2010-02-23 2011-08-25 Valery Alakhov Cyclopolysaccharide compositions
US8383663B2 (en) 2010-07-19 2013-02-26 Supratek Pharma Inc. Bendamustine anionic-catioinic cyclopolysaccharide compositions
JP2014526512A (ja) * 2011-09-18 2014-10-06 ユーロ−セルティーク エス．エイ． 医薬組成物
TWI573792B (zh) 2012-02-01 2017-03-11 歐陸斯迪公司 新穎治療劑
HRP20230276T1 (hr) 2012-03-20 2023-04-28 Eagle Pharmaceuticals, Inc. Tekući pripravci bendamustina za uporabu u postupku liječenja stanja koja reagiraju na bendamustin kod pacijenata kojima za primjenu trebaju reducirani volumeni
DK2827862T3 (da) 2012-03-20 2024-02-12 Eagle Pharmaceuticals Inc Formuleringer af bendamustin
US20230241218A1 (en) * 2012-07-10 2023-08-03 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
EP2925327B1 (en) * 2012-11-30 2024-01-10 The Regents of The University of California Allopregnanolone for treating, reducing or mitigating symptoms of post-partum depression
WO2015031198A2 (en) * 2013-08-27 2015-03-05 Voudouris Vasilios Bendamustine pharmaceutical compositions
GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
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US11266631B2 (en) 2016-10-11 2022-03-08 Purdue Pharmaceutical Products L.P. Hodgkin lymphoma therapy
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
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GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
EP3691637A1 (en) * 2017-10-05 2020-08-12 TUBE Pharmaceuticals GmbH Oral bendamustine formulations
US11730815B2 (en) * 2018-11-26 2023-08-22 Good Health, Llc Stable liquid pharmaceutical compositions comprising bendamustine
WO2020128912A1 (en) 2018-12-18 2020-06-25 Mundipharma International Corporation Limited Compounds for treating lymphoma or a t-cell malignant disease
US20220304983A1 (en) * 2020-04-09 2022-09-29 Bika Biotech (Guangzhou) Co., Ltd Bendamustine composition and use thereof
CN111557904A (zh) * 2020-04-09 2020-08-21 比卡生物科技（广州）有限公司 苯达莫司汀组合物及其用途
US20240148696A1 (en) 2022-10-25 2024-05-09 Softkemo Pharma Inc. Lyophilized bendamustine-cyclodextrin composition

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Also Published As

Publication number Publication date
ES2525257T3 (es) 2014-12-19
CA2753641A1 (en) 2010-09-02
EP2792369B1 (en) 2018-04-18
US20130190372A1 (en) 2013-07-25
CN102421451B (zh) 2013-11-06
CN102935080A (zh) 2013-02-20
AU2010217297A1 (en) 2011-10-20
US8436032B2 (en) 2013-05-07
RU2016124871A (ru) 2018-12-04
RU2734236C2 (ru) 2020-10-13
EP2400987A1 (en) 2012-01-04
KR101798951B1 (ko) 2017-11-20
EP2792369A1 (en) 2014-10-22
US8703964B2 (en) 2014-04-22
CA2753641C (en) 2014-09-16
EP2400987B1 (en) 2014-09-03
HUE038234T2 (hu) 2018-10-29
JP5654498B2 (ja) 2015-01-14
EP2400987A4 (en) 2012-08-22
WO2010097700A1 (en) 2010-09-02
US20100216858A1 (en) 2010-08-26
RU2011138844A (ru) 2013-04-10
CN102421451A (zh) 2012-04-18
KR20120015294A (ko) 2012-02-21
JP2012519657A (ja) 2012-08-30
RU2016124871A3 (enExample) 2019-11-11
ES2675620T3 (es) 2018-07-11
NO2792369T3 (enExample) 2018-09-15

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FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20141030

FZ9A Application not withdrawn (correction of the notice of withdrawal)

Effective date: 20150216

PD4A Correction of name of patent owner
PC41 Official registration of the transfer of exclusive right

Effective date: 20190211