RU2569187C2 - Коллекция и способы ее применения - Google Patents

Коллекция и способы ее применения Download PDF

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Publication number
RU2569187C2
RU2569187C2 RU2011147741/10A RU2011147741A RU2569187C2 RU 2569187 C2 RU2569187 C2 RU 2569187C2 RU 2011147741/10 A RU2011147741/10 A RU 2011147741/10A RU 2011147741 A RU2011147741 A RU 2011147741A RU 2569187 C2 RU2569187 C2 RU 2569187C2
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seq
embryonic type
variable region
pairs
antibodies
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RU2011147741/10A
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English (en)
Russian (ru)
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RU2011147741A (ru
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Маркус ЭНЦЕЛЬБЕРГЕР
Йозеф Прасслер
Штефани Урлингер
Таня ГЕРМАН
Томас Тиллер
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МорфоСис АГ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2011147741/10A 2009-05-29 2010-05-29 Коллекция и способы ее применения RU2569187C2 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US18235009P 2009-05-29 2009-05-29
US61/182,350 2009-05-29
EP09162724 2009-06-15
EP09162724.0 2009-06-15
US29940110P 2010-01-29 2010-01-29
US61/299,401 2010-01-29
PCT/EP2010/057507 WO2010136598A1 (en) 2009-05-29 2010-05-29 A collection and methods for its use

Publications (2)

Publication Number Publication Date
RU2011147741A RU2011147741A (ru) 2013-07-10
RU2569187C2 true RU2569187C2 (ru) 2015-11-20

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EP (1) EP2435568B1 (https=)
JP (1) JP5804521B2 (https=)
KR (1) KR101805202B1 (https=)
CN (1) CN102449149B (https=)
AU (1) AU2010252939B2 (https=)
CA (1) CA2758356C (https=)
DK (1) DK2435568T3 (https=)
ES (1) ES2511051T3 (https=)
IL (1) IL216536B (https=)
MX (1) MX2011012696A (https=)
NZ (1) NZ596603A (https=)
PT (1) PT2435568E (https=)
RU (1) RU2569187C2 (https=)
SG (1) SG175407A1 (https=)
WO (1) WO2010136598A1 (https=)
ZA (1) ZA201107652B (https=)

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Publication number Publication date
CA2758356C (en) 2016-07-26
IL216536B (en) 2018-06-28
ZA201107652B (en) 2012-06-27
US20140163208A1 (en) 2014-06-12
AU2010252939A1 (en) 2011-10-13
US8685896B2 (en) 2014-04-01
US10647757B2 (en) 2020-05-12
KR101805202B1 (ko) 2017-12-07
EP2435568A1 (en) 2012-04-04
KR20120087809A (ko) 2012-08-07
PT2435568E (pt) 2014-10-08
ES2511051T3 (es) 2014-10-22
JP5804521B2 (ja) 2015-11-04
US9624293B2 (en) 2017-04-18
EP2435568B1 (en) 2014-07-02
IL216536A0 (en) 2012-02-29
CN102449149B (zh) 2014-04-23
HK1168635A1 (en) 2013-01-04
CN102449149A (zh) 2012-05-09
RU2011147741A (ru) 2013-07-10
MX2011012696A (es) 2012-03-29
WO2010136598A1 (en) 2010-12-02
SG175407A1 (en) 2011-11-28
JP2012527881A (ja) 2012-11-12
US20170218048A1 (en) 2017-08-03
DK2435568T3 (da) 2014-09-08
CA2758356A1 (en) 2010-12-02
US20120077713A1 (en) 2012-03-29
AU2010252939B2 (en) 2014-06-26
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