MX2011012696A - Una coleccion y metodos para su uso. - Google Patents
Una coleccion y metodos para su uso.Info
- Publication number
- MX2011012696A MX2011012696A MX2011012696A MX2011012696A MX2011012696A MX 2011012696 A MX2011012696 A MX 2011012696A MX 2011012696 A MX2011012696 A MX 2011012696A MX 2011012696 A MX2011012696 A MX 2011012696A MX 2011012696 A MX2011012696 A MX 2011012696A
- Authority
- MX
- Mexico
- Prior art keywords
- class
- prevalent
- present disclosure
- methods
- collection
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
- C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18235009P | 2009-05-29 | 2009-05-29 | |
| EP09162724 | 2009-06-15 | ||
| US29940110P | 2010-01-29 | 2010-01-29 | |
| PCT/EP2010/057507 WO2010136598A1 (en) | 2009-05-29 | 2010-05-29 | A collection and methods for its use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2011012696A true MX2011012696A (es) | 2012-03-29 |
Family
ID=41210731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011012696A MX2011012696A (es) | 2009-05-29 | 2010-05-29 | Una coleccion y metodos para su uso. |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US8685896B2 (https=) |
| EP (1) | EP2435568B1 (https=) |
| JP (1) | JP5804521B2 (https=) |
| KR (1) | KR101805202B1 (https=) |
| CN (1) | CN102449149B (https=) |
| AU (1) | AU2010252939B2 (https=) |
| CA (1) | CA2758356C (https=) |
| DK (1) | DK2435568T3 (https=) |
| ES (1) | ES2511051T3 (https=) |
| IL (1) | IL216536B (https=) |
| MX (1) | MX2011012696A (https=) |
| NZ (1) | NZ596603A (https=) |
| PT (1) | PT2435568E (https=) |
| RU (1) | RU2569187C2 (https=) |
| SG (1) | SG175407A1 (https=) |
| WO (1) | WO2010136598A1 (https=) |
| ZA (1) | ZA201107652B (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
| CA2758356C (en) | 2009-05-29 | 2016-07-26 | Morphosys Ag | A collection of vh and vl pairs having favourable biophysical properties and methods for its use |
| US9796788B2 (en) | 2010-02-08 | 2017-10-24 | Regeneron Pharmaceuticals, Inc. | Mice expressing a limited immunoglobulin light chain repertoire |
| US20130045492A1 (en) | 2010-02-08 | 2013-02-21 | Regeneron Pharmaceuticals, Inc. | Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain |
| US20120021409A1 (en) * | 2010-02-08 | 2012-01-26 | Regeneron Pharmaceuticals, Inc. | Common Light Chain Mouse |
| SMT202600080T1 (it) | 2010-02-08 | 2026-03-09 | Regeneron Pharma | Topo con catena leggera comune |
| US8367586B2 (en) * | 2010-11-19 | 2013-02-05 | Morphosys Ag | Collection and methods for its use |
| AU2012233313C1 (en) | 2011-03-30 | 2017-08-03 | Chugai Seiyaku Kabushiki Kaisha | Method for altering plasma retention and immunogenicity of antigen-binding molecule |
| CN103732738A (zh) * | 2011-04-28 | 2014-04-16 | 小利兰斯坦福大学托管委员会 | 与样品相关的多核苷酸的鉴定 |
| CN103797029B (zh) | 2011-05-17 | 2016-08-17 | 洛克菲勒大学 | 人类免疫缺陷病毒中和抗体及其使用方法 |
| HUE047278T2 (hu) | 2011-08-05 | 2020-04-28 | Regeneron Pharma | Humanizált univerzális könnyûláncú egerek |
| CA2845391C (en) * | 2011-08-18 | 2021-01-19 | Affinity Biosciences Pty Ltd | Soluble polypeptides |
| CA2791109C (en) | 2011-09-26 | 2021-02-16 | Merus B.V. | Generation of binding molecules |
| KR102276528B1 (ko) | 2011-09-30 | 2021-07-12 | 추가이 세이야쿠 가부시키가이샤 | 이온 농도 의존성 결합 분자 라이브러리 |
| JP6322411B2 (ja) | 2011-09-30 | 2018-05-09 | 中外製薬株式会社 | 複数の生理活性を有する抗原の消失を促進する抗原結合分子 |
| EP2752200B1 (en) | 2011-09-30 | 2023-11-01 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule inducing immune response to target antigen |
| EP2793947B1 (en) | 2011-12-23 | 2021-02-03 | Innate Pharma | Enzymatic conjugation of polypeptides |
| EP3539374A1 (en) | 2012-03-16 | 2019-09-18 | Regeneron Pharmaceuticals, Inc. | Non-human animals expressing ph-sensitive immunoglobulin sequences |
| EP2825036B1 (en) | 2012-03-16 | 2018-05-02 | Regeneron Pharmaceuticals, Inc. | Histidine engineered light chain antibodies and genetically modified rodents for generating the same |
| US10132799B2 (en) | 2012-07-13 | 2018-11-20 | Innate Pharma | Screening of conjugated antibodies |
| EP3564259A3 (en) | 2012-11-09 | 2020-02-12 | Innate Pharma | Recognition tags for tgase-mediated conjugation |
| SG11201505941PA (en) * | 2013-02-20 | 2015-09-29 | Affinity Biosciences Pty Ltd | Cytoplasmic expression of fab proteins |
| US10611824B2 (en) | 2013-03-15 | 2020-04-07 | Innate Pharma | Solid phase TGase-mediated conjugation of antibodies |
| EP3010547B1 (en) | 2013-06-20 | 2021-04-21 | Innate Pharma | Enzymatic conjugation of polypeptides |
| CN105517577A (zh) | 2013-06-21 | 2016-04-20 | 先天制药公司 | 多肽的酶促偶联 |
| EP3013361B1 (en) * | 2013-06-24 | 2021-10-06 | NexImmune, Inc. | Compositions and methods for immunotherapy |
| US20150011405A1 (en) * | 2013-07-03 | 2015-01-08 | Atreca, Inc. | Use of Nanoexpression to Interrogate Antigen Repertoires |
| CA3124228C (en) | 2014-03-21 | 2024-05-14 | Regeneron Pharmaceuticals, Inc. | Non-human animals that make single domain binding proteins |
| CA2979702A1 (en) | 2015-03-19 | 2016-09-22 | Regeneron Pharmaceuticals, Inc. | Non-human animals that select for light chain variable regions that bind antigen |
| US10221249B2 (en) * | 2015-09-10 | 2019-03-05 | Affigen, Llc | Method of making patient specific anti-idiotype antibodies |
| FI3652606T3 (fi) | 2017-07-12 | 2023-03-16 | Nouscom Ag | Jaettuihin tuumorineoantigeeneihin perustuva yleisrokote epästabiilien mikrosatelliitti (msi) -syöpien ennaltaehkäisyyn ja hoitoon |
| AU2020359070A1 (en) * | 2019-10-03 | 2022-04-21 | Janssen Biotech, Inc. | Methods for producing biotherapeutics with increased stability by sequence optimization |
| KR20220162151A (ko) * | 2020-03-27 | 2022-12-07 | 디디바이오. 코포레이션 엘티디.,(상하이) | 항원 특이적 결합 폴리펩티드 유전자 디스플레이 벡터의 구축 방법 및 응용 |
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-
2010
- 2010-05-29 CA CA2758356A patent/CA2758356C/en active Active
- 2010-05-29 NZ NZ596603A patent/NZ596603A/xx not_active IP Right Cessation
- 2010-05-29 ES ES10722101.2T patent/ES2511051T3/es active Active
- 2010-05-29 US US13/321,564 patent/US8685896B2/en active Active
- 2010-05-29 DK DK10722101.2T patent/DK2435568T3/da active
- 2010-05-29 WO PCT/EP2010/057507 patent/WO2010136598A1/en not_active Ceased
- 2010-05-29 KR KR1020117031164A patent/KR101805202B1/ko active Active
- 2010-05-29 PT PT107221012T patent/PT2435568E/pt unknown
- 2010-05-29 JP JP2012512407A patent/JP5804521B2/ja active Active
- 2010-05-29 MX MX2011012696A patent/MX2011012696A/es active IP Right Grant
- 2010-05-29 RU RU2011147741/10A patent/RU2569187C2/ru active
- 2010-05-29 SG SG2011079761A patent/SG175407A1/en unknown
- 2010-05-29 AU AU2010252939A patent/AU2010252939B2/en active Active
- 2010-05-29 EP EP10722101.2A patent/EP2435568B1/en active Active
- 2010-05-29 CN CN201080022793.7A patent/CN102449149B/zh active Active
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| CA2758356C (en) | 2016-07-26 |
| IL216536B (en) | 2018-06-28 |
| ZA201107652B (en) | 2012-06-27 |
| US20140163208A1 (en) | 2014-06-12 |
| AU2010252939A1 (en) | 2011-10-13 |
| US8685896B2 (en) | 2014-04-01 |
| US10647757B2 (en) | 2020-05-12 |
| KR101805202B1 (ko) | 2017-12-07 |
| EP2435568A1 (en) | 2012-04-04 |
| KR20120087809A (ko) | 2012-08-07 |
| PT2435568E (pt) | 2014-10-08 |
| ES2511051T3 (es) | 2014-10-22 |
| JP5804521B2 (ja) | 2015-11-04 |
| US9624293B2 (en) | 2017-04-18 |
| EP2435568B1 (en) | 2014-07-02 |
| IL216536A0 (en) | 2012-02-29 |
| CN102449149B (zh) | 2014-04-23 |
| HK1168635A1 (en) | 2013-01-04 |
| CN102449149A (zh) | 2012-05-09 |
| RU2011147741A (ru) | 2013-07-10 |
| WO2010136598A1 (en) | 2010-12-02 |
| RU2569187C2 (ru) | 2015-11-20 |
| SG175407A1 (en) | 2011-11-28 |
| JP2012527881A (ja) | 2012-11-12 |
| US20170218048A1 (en) | 2017-08-03 |
| DK2435568T3 (da) | 2014-09-08 |
| CA2758356A1 (en) | 2010-12-02 |
| US20120077713A1 (en) | 2012-03-29 |
| AU2010252939B2 (en) | 2014-06-26 |
| NZ596603A (en) | 2013-07-26 |
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