RU2563236C2 - Фактор фон виллебранда или фактор viii и фактор фон виллебранда для лечения коагулопатии, индуцированной ингибиторами тромбоцитов - Google Patents
Фактор фон виллебранда или фактор viii и фактор фон виллебранда для лечения коагулопатии, индуцированной ингибиторами тромбоцитов Download PDFInfo
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- RU2563236C2 RU2563236C2 RU2011104705/15A RU2011104705A RU2563236C2 RU 2563236 C2 RU2563236 C2 RU 2563236C2 RU 2011104705/15 A RU2011104705/15 A RU 2011104705/15A RU 2011104705 A RU2011104705 A RU 2011104705A RU 2563236 C2 RU2563236 C2 RU 2563236C2
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| DE102008032361A DE102008032361A1 (de) | 2008-07-10 | 2008-07-10 | Der Einsatz von Faktor VIII und vWF bzw. vWF-enthaltenden Konzentraten zur Therapie der durch Thrombocyten-Inhibitoren induzierte Koagulopathie |
| DE102008032361.6 | 2008-07-10 | ||
| PCT/EP2009/005027 WO2010003687A1 (en) | 2008-07-10 | 2009-07-10 | Von willebrand factor or factor viii and von willebrand factor for the treatment of coagulopathy induced by inhibitors of thrombocytes |
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| RU2011104705A RU2011104705A (ru) | 2012-08-20 |
| RU2563236C2 true RU2563236C2 (ru) | 2015-09-20 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2698392C2 (ru) * | 2008-06-24 | 2019-08-26 | Октафарма Аг | Способ очистки фактора свертывания крови viii |
| RU2851973C2 (ru) * | 2017-07-07 | 2025-12-02 | Такеда Фармасьютикал Компани Лимитед | Лечение пациентов с тяжелой формой болезни фон виллебранда, подвергающихся плановому хирургическому вмешательству, путем введения рекомбинантного ффв |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11197916B2 (en) | 2007-12-28 | 2021-12-14 | Takeda Pharmaceutical Company Limited | Lyophilized recombinant VWF formulations |
| JP5784907B2 (ja) | 2007-12-28 | 2015-09-24 | バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ | 組換え型ｖｗｆ製剤 |
| DE102008032361A1 (de) * | 2008-07-10 | 2010-01-21 | Csl Behring Gmbh | Der Einsatz von Faktor VIII und vWF bzw. vWF-enthaltenden Konzentraten zur Therapie der durch Thrombocyten-Inhibitoren induzierte Koagulopathie |
| AR074054A1 (es) | 2008-10-21 | 2010-12-22 | Baxter Healthcare Sa | Formulaciones farmaceuticas de factor de von willebrand recombinante liofilizado |
| RS59670B1 (sr) | 2012-01-12 | 2020-01-31 | Bioverativ Therapeutics Inc | Himerni polipeptidi faktora viii i njihove upotrebe |
| WO2013083858A1 (en) | 2012-04-24 | 2013-06-13 | Novo Nordisk A/S | Compounds suitable for treatment of haemophilia |
| EP2662083A1 (en) * | 2012-05-08 | 2013-11-13 | CSL Behring GmbH | Sugar compositions for treating hemophilia a and/or von willebrand disease |
| CN102776260B (zh) * | 2012-07-26 | 2015-04-29 | 上海泰龙生物医药科技有限公司 | 一种高效表达重组人凝血八因子的方法 |
| DK2796145T3 (da) | 2013-04-22 | 2018-01-29 | Csl Ltd | Et kovalent kompleks af von Willebrand-faktor og faktor VIII linket af en disulfidbro |
| CN103263663B (zh) * | 2013-06-08 | 2016-05-04 | 兆科药业（合肥）有限公司 | 一种抗血小板溶栓素在制备治疗vwf缺陷型血管栓塞性疾病的药物中的应用 |
| US10231993B2 (en) | 2013-06-27 | 2019-03-19 | University Of Washington Through Its Center For Commercialization | Biocompatible polymeric system for targeted treatment of thrombotic and hemostatic disorders |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571784A (en) * | 1994-10-20 | 1996-11-05 | Behringwerke Aktiengesellschaft | Use of VWF-containing concentrates as a therapy which is employed in combination with antithrombotic and fibrinolytic therapy |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4430205A1 (de) | 1994-08-26 | 1996-02-29 | Behringwerke Ag | Zusammensetzungen, die als Gegenmittel für Blut-Antikoagulanzien geeignet sind und deren Verwendung |
| US6518482B2 (en) | 1994-09-13 | 2003-02-11 | American National Red Cross | Transgenic non-human mammals expressing human coagulation factor VIII and von Willebrand factor |
| FR2744918B1 (fr) | 1996-02-19 | 1998-05-07 | Sanofi Sa | Nouvelles associations de principes actifs contenant un derive de thieno(3,2-c)pyridine et un antithrombotique |
| FI974321A0 (fi) * | 1997-11-25 | 1997-11-25 | Jenny Ja Antti Wihurin Rahasto | Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa |
| WO2001047547A1 (en) † | 1999-12-24 | 2001-07-05 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Medicinal compositions for preventing and treating hemorrhagic diseases associating thrombopathy |
| DE102008032361A1 (de) * | 2008-07-10 | 2010-01-21 | Csl Behring Gmbh | Der Einsatz von Faktor VIII und vWF bzw. vWF-enthaltenden Konzentraten zur Therapie der durch Thrombocyten-Inhibitoren induzierte Koagulopathie |
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2008
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571784A (en) * | 1994-10-20 | 1996-11-05 | Behringwerke Aktiengesellschaft | Use of VWF-containing concentrates as a therapy which is employed in combination with antithrombotic and fibrinolytic therapy |
Non-Patent Citations (1)
| Title |
|---|
| BERNTORP ERIC et al. "A systematic overview of the first pasteurised VWF/FVIII medicinal product, Haemate (R) P/Humatee (R)-P: History and performance"// European Journal of Hematology, vol.80,no.Suppl.70, May 2008, pages 3-35. ШУМАКОВ В.А. и др. Антитромбоцитарная терапия у больных ИБС: клопидогрель и/или ацетилсалициловая кислота? Ж.Новая Медицина Тысячелетия Эндокринология, 2007 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2698392C2 (ru) * | 2008-06-24 | 2019-08-26 | Октафарма Аг | Способ очистки фактора свертывания крови viii |
| RU2851973C2 (ru) * | 2017-07-07 | 2025-12-02 | Такеда Фармасьютикал Компани Лимитед | Лечение пациентов с тяжелой формой болезни фон виллебранда, подвергающихся плановому хирургическому вмешательству, путем введения рекомбинантного ффв |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010003687A1 (en) | 2010-01-14 |
| US20110112023A1 (en) | 2011-05-12 |
| EP2310043B1 (en) | 2012-09-19 |
| CA2730290C (en) | 2017-02-07 |
| AU2009268289A1 (en) | 2010-01-14 |
| PL2310043T5 (pl) | 2024-02-05 |
| ES2395855T5 (es) | 2022-09-06 |
| JP5653916B2 (ja) | 2015-01-14 |
| CA2730290A1 (en) | 2010-01-14 |
| ES2395855T3 (es) | 2013-02-15 |
| PL2310043T3 (pl) | 2013-02-28 |
| DE102008032361A1 (de) | 2010-01-21 |
| JP2011527301A (ja) | 2011-10-27 |
| US8603979B2 (en) | 2013-12-10 |
| RU2011104705A (ru) | 2012-08-20 |
| US20140128325A1 (en) | 2014-05-08 |
| EP2310043A1 (en) | 2011-04-20 |
| KR20110043654A (ko) | 2011-04-27 |
| EP2310043B2 (en) | 2022-05-18 |
| DK2310043T4 (da) | 2022-06-20 |
| AU2009268289B2 (en) | 2014-11-06 |
| CN102088999A (zh) | 2011-06-08 |
| US9095564B2 (en) | 2015-08-04 |
| DK2310043T3 (da) | 2013-01-07 |
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