RU2558931C2 - Способы предсказания ответа трижды негативного рака молочной железы на терапию - Google Patents

Способы предсказания ответа трижды негативного рака молочной железы на терапию Download PDF

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RU2558931C2
RU2558931C2 RU2012134390/15A RU2012134390A RU2558931C2 RU 2558931 C2 RU2558931 C2 RU 2558931C2 RU 2012134390/15 A RU2012134390/15 A RU 2012134390/15A RU 2012134390 A RU2012134390 A RU 2012134390A RU 2558931 C2 RU2558931 C2 RU 2558931C2
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expression
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vegfr2
activation
antibodies
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RU2012134390/15A
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RU2012134390A (ru
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Ксиньдзунь ЛИУ
Филип КИМ
Ричард КИРКЛЭНД
Тани ЛИ
Белен ИБАРРОНДО
Шарат СИНГХ
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Нестек С.А.
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • General Physics & Mathematics (AREA)
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  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
RU2012134390/15A 2010-01-12 2011-01-12 Способы предсказания ответа трижды негативного рака молочной железы на терапию RU2558931C2 (ru)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US29443310P 2010-01-12 2010-01-12
US61/294,433 2010-01-12
US32562410P 2010-04-19 2010-04-19
US61/325,624 2010-04-19
US32860210P 2010-04-27 2010-04-27
US61/328,602 2010-04-27
US35183810P 2010-06-04 2010-06-04
US61/351,838 2010-06-04
PCT/US2011/021026 WO2011088149A2 (en) 2010-01-12 2011-01-12 Methods for predicting response of triple-negative breast cancer to therapy

Publications (2)

Publication Number Publication Date
RU2012134390A RU2012134390A (ru) 2014-02-20
RU2558931C2 true RU2558931C2 (ru) 2015-08-10

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RU2012134390/15A RU2558931C2 (ru) 2010-01-12 2011-01-12 Способы предсказания ответа трижды негативного рака молочной железы на терапию

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US (2) US9488654B2 (enExample)
EP (1) EP2524232B1 (enExample)
JP (1) JP5764144B2 (enExample)
KR (1) KR20120115390A (enExample)
CN (1) CN102822676B (enExample)
AU (1) AU2011205343B2 (enExample)
BR (1) BR112012017084A2 (enExample)
CA (1) CA2787225A1 (enExample)
ES (1) ES2505466T3 (enExample)
IL (1) IL220833A0 (enExample)
MX (1) MX2012008153A (enExample)
NZ (1) NZ601348A (enExample)
RU (1) RU2558931C2 (enExample)
WO (1) WO2011088149A2 (enExample)
ZA (1) ZA201206019B (enExample)

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RU2616533C1 (ru) * 2016-03-15 2017-04-17 Федеральное государственное бюджетное научное учреждение "Томский научно-исследовательский институт онкологии" (Томский НИИ онкологии) Способ прогнозирования эффективности терапии эверолимусом у больных метастатическим раком почки

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EP2788752B1 (en) * 2011-12-05 2018-10-03 Pierian Holdings, Inc. Method of therapy selection for patients with lung cancer
CA2862835A1 (en) * 2012-01-13 2013-07-18 Genentech, Inc. Biological markers for identifying patients for treatment with vegf antagonists
WO2014001232A1 (en) * 2012-06-26 2014-01-03 F. Hoffmann-La Roche Ag Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer
US9422602B2 (en) 2012-08-15 2016-08-23 Bio-Rad Laboratories, Inc. Methods and compositions for determining nucleic acid degradation
WO2014071218A2 (en) * 2012-11-02 2014-05-08 University Of Utah Research Foundation Biomarkers for breast cancer and methods of using same
KR20140096571A (ko) 2013-01-28 2014-08-06 한미약품 주식회사 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법
WO2015028974A2 (en) * 2013-08-30 2015-03-05 Nestec S.A. Polyp recurrence
ES2763429T5 (es) * 2013-12-17 2023-06-21 Hoffmann La Roche Procedimientos de tratamiento de cánceres usando antagonistas de la unión al eje de PD-1 y taxanos
EP3006940A1 (en) * 2014-10-10 2016-04-13 Ruprecht-Karls-Universität Heidelberg Biomarkers for predicting the response to anti-angiogenic cancer therapy
CN105891496A (zh) * 2014-12-09 2016-08-24 上海华盈生物医药科技有限公司 酪氨酸激酶抑制剂类靶向用药指导抗体芯片和检测方法
CN104830775B (zh) * 2015-04-14 2019-06-21 上海中医药大学附属龙华医院 一种三阴性乳腺癌顺铂耐药细胞株及其制备方法和用途
HRP20260689T1 (hr) 2015-06-17 2026-07-17 F. Hoffmann-La Roche Ag Postupci za liječenje lokalno uznapredovalog ili metastatskog raka dojke primjenom antagonista vezivanja osi pd-1 i taksana
US20180303830A1 (en) * 2015-06-22 2018-10-25 Thomas Jefferson University Cancers expressing ccr5 and methods of treatment of same
EP3363911B1 (en) * 2015-10-14 2024-09-25 Nitto Boseki Co., Ltd. Method for determining drug-sensitive human breast cancer cells by analysis method in which measurement of activity of two types of protein kinase is used
IL245861A0 (en) 2016-05-25 2016-09-04 Yeda Res & Dev Use of substances to treat drug-resistant tumors
CN109789204A (zh) * 2016-05-31 2019-05-21 雀巢产品技术援助有限公司 基于her2和her3通路亚型选择乳癌患者药物疗法的方法
CN106645728A (zh) * 2016-11-09 2017-05-10 百奥森（江苏）食品安全科技有限公司 一种食品中氟喹诺酮类药物的检测试剂盒
RU2648523C1 (ru) * 2017-05-22 2018-03-26 Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр" Российской академии наук ("Томский НИМЦ") Способ прогнозирования исхода заболевания у больных люминальным в и трижды негативным раком молочной железы у пациенток, не получавших в неоадъювантном режиме химио- или гормонотерапию
CN109470854B (zh) * 2017-09-08 2022-02-11 广州市丹蓝生物科技有限公司 肺癌诊断用蛋白芯片及试剂盒
WO2019217942A1 (en) 2018-05-11 2019-11-14 Beam Therapeutics Inc. Methods of substituting pathogenic amino acids using programmable base editor systems
US20210088523A1 (en) * 2019-09-23 2021-03-25 Sri International Methods for detecting circulating tumor cells in non-small cell lung cancer
US11366101B1 (en) 2020-12-31 2022-06-21 Elephas Biosciences Corporation Ex vivo systems and methods for determining the effect of a drug or other agent on a tissue
CN120731084A (zh) * 2023-03-15 2025-09-30 侯明宏 用于治疗三阴性乳癌的药物组合物

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
RU2616533C1 (ru) * 2016-03-15 2017-04-17 Федеральное государственное бюджетное научное учреждение "Томский научно-исследовательский институт онкологии" (Томский НИИ онкологии) Способ прогнозирования эффективности терапии эверолимусом у больных метастатическим раком почки

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KR20120115390A (ko) 2012-10-17
AU2011205343A1 (en) 2012-08-02
US10697967B2 (en) 2020-06-30
US9488654B2 (en) 2016-11-08
JP5764144B2 (ja) 2015-08-12
ZA201206019B (en) 2015-06-24
WO2011088149A3 (en) 2011-10-27
CN102822676B (zh) 2015-02-18
AU2011205343B2 (en) 2015-08-13
MX2012008153A (es) 2012-11-06
BR112012017084A2 (pt) 2016-04-12
CN102822676A (zh) 2012-12-12
EP2524232A2 (en) 2012-11-21
EP2524232A4 (en) 2013-06-12
HK1178602A1 (en) 2013-09-13
US20130012407A1 (en) 2013-01-10
US20170227542A1 (en) 2017-08-10
WO2011088149A2 (en) 2011-07-21
IL220833A0 (en) 2012-08-30
CA2787225A1 (en) 2011-07-21
EP2524232B1 (en) 2014-08-06
JP2013517461A (ja) 2013-05-16
ES2505466T3 (es) 2014-10-10
RU2012134390A (ru) 2014-02-20
NZ601348A (en) 2014-07-25

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