RU2553343C2 - Композиции прокариотической фенилаланин-аммиак-лиазы и способы лечения рака с использованием таких композиций - Google Patents

Композиции прокариотической фенилаланин-аммиак-лиазы и способы лечения рака с использованием таких композиций Download PDF

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RU2553343C2
RU2553343C2 RU2012134838/15A RU2012134838A RU2553343C2 RU 2553343 C2 RU2553343 C2 RU 2553343C2 RU 2012134838/15 A RU2012134838/15 A RU 2012134838/15A RU 2012134838 A RU2012134838 A RU 2012134838A RU 2553343 C2 RU2553343 C2 RU 2553343C2
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avpal
stabilizer
amount
per mole
phenylalanine
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RU2012134838A (ru
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Мишель К. Веллар
Пол А. Фитцпатрик
Эмиль Д. Каккис
Дэниел Дж. Вендт
Мубарак МУТХАЛИФ
Шон М. БЕЛЛ
Аугустус О. Окхамафе
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Байомарин Фармасьютикал Инк.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2012134838/15A 2007-08-17 2008-08-15 Композиции прокариотической фенилаланин-аммиак-лиазы и способы лечения рака с использованием таких композиций RU2553343C2 (ru)

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US6612507P 2007-08-17 2007-08-17
US61/066,125 2007-08-17

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RU2553343C2 true RU2553343C2 (ru) 2015-06-10

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RU2009141987/15A RU2009141987A (ru) 2007-08-17 2008-08-15 Композиции прокариотической фенилаланин-аммиак-лиазы и способы лечения рака с использованием таких композиций

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CL (1) CL2008002390A1 (enExample)
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MX (1) MX2009012261A (enExample)
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PL (1) PL2175875T3 (enExample)
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RU (2) RU2553343C2 (enExample)
SI (1) SI2175875T1 (enExample)
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WO (1) WO2009025760A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2815197C2 (ru) * 2019-02-14 2024-03-12 Сом Инновейшн Биотек, С.А. Триамтерен или нолатрексед для применения в лечении фенилкетонурии
US12257253B2 (en) 2019-02-14 2025-03-25 Som Innovation Biotech, S.A. Triamterene or nolatrexed for use in the treatment of phenylketonuria

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2815197C2 (ru) * 2019-02-14 2024-03-12 Сом Инновейшн Биотек, С.А. Триамтерен или нолатрексед для применения в лечении фенилкетонурии
US12257253B2 (en) 2019-02-14 2025-03-25 Som Innovation Biotech, S.A. Triamterene or nolatrexed for use in the treatment of phenylketonuria

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CL2008002390A1 (es) 2009-05-29
US7537923B2 (en) 2009-05-26
HUE029510T2 (hu) 2017-02-28
PT2175875T (pt) 2016-11-21
BRPI0811589B1 (pt) 2020-05-12
EP2175875B1 (en) 2016-10-05
ES2602618T3 (es) 2017-02-21
AR067972A1 (es) 2009-10-28
JP5584120B2 (ja) 2014-09-03
DK2175875T3 (en) 2016-11-21
WO2009025760A2 (en) 2009-02-26
AU2008289549B2 (en) 2014-02-06
HUE029510T4 (en) 2017-05-29
EP2175875A2 (en) 2010-04-21
PL2175875T3 (pl) 2017-04-28
RU2012134838A (ru) 2014-03-20
SI2175875T1 (sl) 2017-01-31
BR122018072594B8 (pt) 2021-07-27
LT2175875T (lt) 2016-12-12
BR122018072594B1 (pt) 2020-10-27
BRPI0811589B8 (pt) 2021-05-25
US7560263B2 (en) 2009-07-14
HRP20161474T1 (hr) 2016-12-30
WO2009025760A3 (en) 2009-06-25
AR117389A2 (es) 2021-08-04
MX2009012261A (es) 2010-03-15
RU2009141987A (ru) 2011-05-20
CA2687028C (en) 2016-02-16
CN101803492B (zh) 2014-05-07
CN101803492A (zh) 2010-08-11
JP2010536759A (ja) 2010-12-02
AU2008289549A1 (en) 2009-02-26
CY1118222T1 (el) 2017-06-28
US7790433B2 (en) 2010-09-07
US20090047265A1 (en) 2009-02-19
PE20090605A1 (es) 2009-05-16
US20090047268A1 (en) 2009-02-19
CA2687028A1 (en) 2009-02-26
US20090263369A1 (en) 2009-10-22
US20100278802A1 (en) 2010-11-04
TW200911283A (en) 2009-03-16
TWI418787B (zh) 2013-12-11
BRPI0811589A2 (pt) 2014-10-29

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