RU2535970C2 - Варианты гемагглютинина и нейраминидазы гриппа - Google Patents

Варианты гемагглютинина и нейраминидазы гриппа Download PDF

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RU2535970C2
RU2535970C2 RU2011137404/10A RU2011137404A RU2535970C2 RU 2535970 C2 RU2535970 C2 RU 2535970C2 RU 2011137404/10 A RU2011137404/10 A RU 2011137404/10A RU 2011137404 A RU2011137404 A RU 2011137404A RU 2535970 C2 RU2535970 C2 RU 2535970C2
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seq
residues
sequences
polypeptide
influenza
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RU2011137404/10A
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RU2011137404A (ru
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Хонг ДЗИН
Син ЧЭН
Канта СУББАРАО
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МЕДИММЬЮН, ЭлЭлСи
Дзе Гавернмент Оф Дзе Юнайтед Стейтс Оф Америка Нэшнл Инститьютс Оф Хелт
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pulmonology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2011137404/10A 2009-02-12 2010-02-03 Варианты гемагглютинина и нейраминидазы гриппа RU2535970C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15209409P 2009-02-12 2009-02-12
US61/152,094 2009-02-12
PCT/US2010/022970 WO2010093537A2 (en) 2009-02-12 2010-02-03 Influenza hemagglutinin and neuraminidase variants

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RU2011137404A RU2011137404A (ru) 2013-03-20
RU2535970C2 true RU2535970C2 (ru) 2014-12-20

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US (2) US8613935B2 (cg-RX-API-DMAC7.html)
EP (1) EP2396033B1 (cg-RX-API-DMAC7.html)
JP (1) JP5818693B2 (cg-RX-API-DMAC7.html)
CN (1) CN102361649A (cg-RX-API-DMAC7.html)
AU (1) AU2010213966B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI1008549A2 (cg-RX-API-DMAC7.html)
CA (1) CA2752205A1 (cg-RX-API-DMAC7.html)
MX (2) MX2011008497A (cg-RX-API-DMAC7.html)
RU (2) RU2535970C2 (cg-RX-API-DMAC7.html)
SG (2) SG2014010185A (cg-RX-API-DMAC7.html)
WO (1) WO2010093537A2 (cg-RX-API-DMAC7.html)

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CA2752205A1 (en) 2009-02-12 2010-08-19 Medimmune, Llc Influenza hemagglutinin and neuraminidase variants
WO2012040406A2 (en) * 2010-09-21 2012-03-29 Massachusetts Institute Of Technology Influenza treatment and/or characterization; human-adapted ha polypeptides; vaccines
CN108103084B (zh) * 2017-11-21 2020-06-26 浙江迪福润丝生物科技有限公司 区分免疫和感染动物h5亚型禽流感疫苗株及其制备方法和应用

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US4752473A (en) * 1984-10-12 1988-06-21 The Regents Of The University Of California Expression of glycosylated human influenza hemagglutinin proteins
WO2003075955A1 (en) * 2002-03-13 2003-09-18 Lg Life Sciences Ltd. Method for enhancing immune responses by codelivering influenza np dna in dna immunization
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JP2012517239A (ja) 2012-08-02
EP2396033B1 (en) 2016-09-28
SG173642A1 (en) 2011-09-29
CA2752205A1 (en) 2010-08-19
US20140079726A1 (en) 2014-03-20
BRPI1008549A2 (pt) 2016-03-15
US8613935B2 (en) 2013-12-24
AU2010213966B2 (en) 2015-01-22
US20100330118A1 (en) 2010-12-30
WO2010093537A2 (en) 2010-08-19
CN102361649A (zh) 2012-02-22
MX2011008497A (es) 2011-12-16
AU2010213966A1 (en) 2011-09-01
US9119812B2 (en) 2015-09-01
EP2396033A2 (en) 2011-12-21
EP2396033A4 (en) 2013-10-23
JP5818693B2 (ja) 2015-11-18
MX343411B (es) 2016-11-04
SG2014010185A (en) 2014-06-27
RU2014140731A (ru) 2016-04-27
WO2010093537A3 (en) 2010-10-07
RU2011137404A (ru) 2013-03-20

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