RU2534606C2 - Мышьякорганические соединения и способы лечения рака - Google Patents
Мышьякорганические соединения и способы лечения рака Download PDFInfo
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- RU2534606C2 RU2534606C2 RU2011110392/14A RU2011110392A RU2534606C2 RU 2534606 C2 RU2534606 C2 RU 2534606C2 RU 2011110392/14 A RU2011110392/14 A RU 2011110392/14A RU 2011110392 A RU2011110392 A RU 2011110392A RU 2534606 C2 RU2534606 C2 RU 2534606C2
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- Prior art keywords
- lymphoma
- alkyl
- hours
- compound
- arsenic
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- A61K31/28—Compounds containing heavy metals
- A61K31/285—Arsenic compounds
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
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- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
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| TWI617305B (zh) * | 2013-12-05 | 2018-03-11 | 蘇愛康制藥有限公司 | 治療癌症的化合物及其應用程序 |
| CN104151397A (zh) * | 2014-07-03 | 2014-11-19 | 北京大学 | 一类新型三硫杂二环有机砷化物及其合成方法和在抗肿瘤领域里的应用 |
| JP6413969B2 (ja) * | 2015-07-29 | 2018-10-31 | 住友金属鉱山株式会社 | 日射遮蔽体形成用分散液および当該分散液を用いた日射遮蔽体 |
| JPWO2019220961A1 (ja) * | 2018-05-18 | 2020-05-28 | ソレイジア・ファーマ株式会社 | ダリナパルシンのアルカリ金属塩及び／又は無機酸付加塩の結晶型及びその製剤 |
| US11998654B2 (en) | 2018-07-12 | 2024-06-04 | Bard Shannon Limited | Securing implants and medical devices |
| CN113408945B (zh) * | 2021-07-15 | 2023-03-24 | 广西中烟工业有限责任公司 | 一种烤烟纯度的检测方法、装置、电子设备及存储介质 |
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| US2349729A (en) | 1940-08-24 | 1944-05-23 | Parke Davis & Co | Therapeutic arsenic preparation |
| EP1391206B1 (en) | 1997-10-15 | 2008-07-02 | Polarx Biopharmaceuticals, Inc. | Pharmaceutical compositions comprising arsenic trioxide for the treatment of non-Hodgkin's lymphoma |
| IL136051A0 (en) | 1997-11-10 | 2001-05-20 | Sloan Kettering Inst Cancer | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| CN1233476A (zh) | 1998-04-24 | 1999-11-03 | 陆道培 | 治疗急性白血病的药物及其制备方法 |
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| KR20030014208A (ko) | 2000-04-26 | 2003-02-15 | 오레곤 헬스 사이언시즈 유니버시티 | 티올계 화학보호제 화합물의 투여 |
| DE10132625A1 (de) | 2001-07-05 | 2003-01-23 | Oce Printing Systems Gmbh | Verfahren, Computerprogrammprodukt und Gerätesystem zum visuellen Überprüfen von Bilddaten |
| JP4571408B2 (ja) | 2002-01-07 | 2010-10-27 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 癌治療薬としての、ｓ−ジメチルアルシノ−チオコハク酸、ｓ−ジメチルアルシノ−２−チオ安息香酸、ｓ−（ジメチルアルシノ）グルタチオン |
| ES2532666T3 (es) * | 2005-07-29 | 2015-03-30 | Solasia Pharma K.K. | Compuestos y métodos para el tratamiento del cáncer |
| CN101395166B (zh) * | 2006-01-13 | 2014-07-09 | 得克萨斯州A&M大学系统 | 用于治疗癌症的化合物和方法 |
| TW200829261A (en) | 2006-09-29 | 2008-07-16 | Ziopharm Oncology Inc | Method for controlling angiogenesis in animals |
| WO2009011893A2 (en) * | 2007-07-17 | 2009-01-22 | Combinatorx, Incorporated | Treatments of b-cell proliferative disorders |
| EP2178370A4 (en) * | 2007-07-17 | 2011-01-12 | Zalicus Inc | COMBINATIONS FOR THE TREATMENT OF PROLIFERATIVE B-CELL DISEASES |
| CN101903029B (zh) * | 2007-11-02 | 2012-09-26 | Zio医药肿瘤学公司 | 使用有机砷化物的联合治疗 |
| WO2009151569A2 (en) * | 2008-06-09 | 2009-12-17 | Combinatorx, Incorporated | Beta adrenergic receptor agonists for the treatment of b-cell proliferative disorders |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060128682A1 (en) * | 2004-07-16 | 2006-06-15 | The Texas A&M University System | Compounds and methods for the treatment of cancer |
Non-Patent Citations (1)
| Title |
|---|
| SAKURAI T. et al. Toxicity of trivalent organic arsenic compound, dimethylarsinous glutathione in a rat liver cell line (TRL 1215)// British J.Pharmacol. 2006, 149, pp.888-897. CHEN G.-Q. et al. Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells// Cancer Res. 63, April 15, 2003, 1853-1859 * |
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