SG10201810450QA - Organoarsenic compounds and methods for the treatment of cancer - Google Patents

Organoarsenic compounds and methods for the treatment of cancer

Info

Publication number
SG10201810450QA
SG10201810450QA SG10201810450QA SG10201810450QA SG10201810450QA SG 10201810450Q A SG10201810450Q A SG 10201810450QA SG 10201810450Q A SG10201810450Q A SG 10201810450QA SG 10201810450Q A SG10201810450Q A SG 10201810450QA SG 10201810450Q A SG10201810450Q A SG 10201810450QA
Authority
SG
Singapore
Prior art keywords
cancer
treatment
methods
organoarsenic compounds
organoarsenic
Prior art date
Application number
SG10201810450QA
Inventor
Brian Eric Schwartz
Jonathan Lewis
Philip B Komarnitsky
Original Assignee
Solasia Pharma K K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solasia Pharma K K filed Critical Solasia Pharma K K
Publication of SG10201810450QA publication Critical patent/SG10201810450QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/285Arsenic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

OrganoarsenicCompounds And Methods For The Treatment Of Cancer A method for treating a lymphoma selected from non-Hodgkin's and Hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (I) wherein X is S or Se and Rl and R are independently Cl-30alkyl (R3, R3', R4, R5, W and "n" are as defined in claim 1 ) in particular where the compound is S- dimethylarsinoglutathione, N-(2-S-dimethylarsinothiopropionyl)glycine, 2- amino-3- (dimethylarsino)thio-3-methylbutanoic acid, S-dimethylarsino-thiosuccinic acid or S- dipropylarsino-1 - thioglycerol. (I) W -41-
SG10201810450QA 2008-08-20 2009-08-14 Organoarsenic compounds and methods for the treatment of cancer SG10201810450QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18951108P 2008-08-20 2008-08-20

Publications (1)

Publication Number Publication Date
SG10201810450QA true SG10201810450QA (en) 2018-12-28

Family

ID=41707414

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201810450QA SG10201810450QA (en) 2008-08-20 2009-08-14 Organoarsenic compounds and methods for the treatment of cancer
SG10201810449XA SG10201810449XA (en) 2008-08-20 2009-08-14 Organoarsenic compounds and methods for the treatment of cancer
SG10201403869TA SG10201403869TA (en) 2008-08-20 2009-08-14 Organoarsenic compounds and methods for the treatment of cancer

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG10201810449XA SG10201810449XA (en) 2008-08-20 2009-08-14 Organoarsenic compounds and methods for the treatment of cancer
SG10201403869TA SG10201403869TA (en) 2008-08-20 2009-08-14 Organoarsenic compounds and methods for the treatment of cancer

Country Status (19)

Country Link
US (4) US20110269697A1 (en)
EP (2) EP2321012B1 (en)
JP (5) JP5933896B2 (en)
KR (3) KR20170103023A (en)
CN (2) CN102149432A (en)
AU (1) AU2009282972A1 (en)
BR (1) BRPI0918407A2 (en)
CA (1) CA2734650A1 (en)
DK (2) DK2321012T3 (en)
ES (2) ES2901426T3 (en)
HK (2) HK1254607A1 (en)
IL (1) IL211153A0 (en)
MX (1) MX2011001800A (en)
NZ (1) NZ591181A (en)
PT (2) PT2321012T (en)
RU (1) RU2534606C2 (en)
SG (3) SG10201810450QA (en)
WO (1) WO2010021928A1 (en)
ZA (1) ZA201101216B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015085208A1 (en) * 2013-12-05 2015-06-11 Solasia Pharma K.K. Compounds and methods for the treatment of cancer
CN104151397A (en) * 2014-07-03 2014-11-19 北京大学 Novel thiabicyclo organic arsenide compound and synthesis method thereof, as well as application in anti-tumor field
JP6413969B2 (en) * 2015-07-29 2018-10-31 住友金属鉱山株式会社 Dispersion for forming solar shading body and solar shading body using the dispersion
JPWO2019220961A1 (en) * 2018-05-18 2020-05-28 ソレイジア・ファーマ株式会社 Crystalline form of darinaparcin alkali metal salt and/or inorganic acid addition salt and preparation thereof
CN113408945B (en) * 2021-07-15 2023-03-24 广西中烟工业有限责任公司 Method and device for detecting purity of flue-cured tobacco, electronic equipment and storage medium

Family Cites Families (19)

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US234972A (en) 1880-11-30 William ennis
US761900A (en) 1904-03-05 1904-06-07 Newton Jefferson Norman Flux compound.
US2349729A (en) 1940-08-24 1944-05-23 Parke Davis & Co Therapeutic arsenic preparation
EP1374875A3 (en) 1997-10-15 2004-01-07 Polarx Biopharmaceuticals, Inc. Pharmaceutical compositons comprising arsenic for the treatment of myelodysplastic syndrome
JP2001522799A (en) 1997-11-10 2001-11-20 メモリアル スローン−ケタリング キャンサー センター Method for producing arsenic trioxide preparation and method for treating cancer using arsenic trioxide or melarsoprol
CN1233476A (en) 1998-04-24 1999-11-03 陆道培 Medicine for treating acute leukemia, and method for preparing same
EP1002537A1 (en) 1998-10-30 2000-05-24 Assistance Publique, Hopitaux De Paris Use of melarsoprol for the manufacture of a medicament for treating B-cell lymphoproliferative diseases, such as multiple myeloma
US6191123B1 (en) 1999-03-19 2001-02-20 Parker Hughes Institute Organic-arsenic compounds
AU2001253919B2 (en) 2000-04-26 2006-12-14 Government Of The United States, D/B/A Department Of Veterans Affairs Administration of a thiol-based chemoprotectant compound
DE10132625A1 (en) 2001-07-05 2003-01-23 Oce Printing Systems Gmbh Process, computer program product and device system for visually checking image data
JP4571408B2 (en) 2002-01-07 2010-10-27 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム S-dimethylarsino-thiosuccinic acid, S-dimethylarsino-2-thiobenzoic acid, S- (dimethylarsino) glutathione as cancer therapeutic agents
TW201350113A (en) * 2004-07-16 2013-12-16 Texas A & M Univ Sys Organic arsenic compounds, uses of the same in treating cancer and pharmaceutical compositions comprising the same
EP1919564B1 (en) * 2005-07-29 2014-11-26 Ziopharm Oncology, Inc. Compounds and methods for the treatment of cancer
EP1979368B1 (en) * 2006-01-13 2014-12-24 The Texas A&M University System Compounds and methods for the treatment of cancer
TW200829261A (en) 2006-09-29 2008-07-16 Ziopharm Oncology Inc Method for controlling angiogenesis in animals
US20090047243A1 (en) * 2007-07-17 2009-02-19 Richard Rickles Combinations for the treatment of b-cell proliferative disorders
AU2008276451A1 (en) * 2007-07-17 2009-01-22 Zalicus Inc. Treatments of B-cell proliferative disorders
KR20100100835A (en) * 2007-11-02 2010-09-15 지오팜 온콜로지 인코포레이티드 Combination therapy with organic arsenicals
WO2009151569A2 (en) * 2008-06-09 2009-12-17 Combinatorx, Incorporated Beta adrenergic receptor agonists for the treatment of b-cell proliferative disorders

Also Published As

Publication number Publication date
HK1254607A1 (en) 2019-07-26
US11324714B2 (en) 2022-05-10
KR20170103023A (en) 2017-09-12
AU2009282972A1 (en) 2010-02-25
JP5933896B2 (en) 2016-06-15
JP2018039853A (en) 2018-03-15
US20110269697A1 (en) 2011-11-03
PT3388111T (en) 2021-12-23
US20210038556A1 (en) 2021-02-11
IL211153A0 (en) 2011-04-28
ZA201101216B (en) 2011-10-26
DK2321012T3 (en) 2018-12-03
ES2703740T3 (en) 2019-03-12
EP3388111B1 (en) 2021-09-29
WO2010021928A1 (en) 2010-02-25
US20210038557A1 (en) 2021-02-11
SG10201403869TA (en) 2014-10-30
NZ591181A (en) 2012-09-28
HK1212218A1 (en) 2016-06-10
CN102149432A (en) 2011-08-10
CA2734650A1 (en) 2010-02-25
SG10201810449XA (en) 2018-12-28
US20150231107A1 (en) 2015-08-20
DK3388111T3 (en) 2021-12-06
ES2901426T3 (en) 2022-03-22
JP2017002081A (en) 2017-01-05
KR20180103194A (en) 2018-09-18
EP3388111A1 (en) 2018-10-17
US10842769B2 (en) 2020-11-24
BRPI0918407A2 (en) 2015-11-24
EP2321012A1 (en) 2011-05-18
JP2012500271A (en) 2012-01-05
CN104800828A (en) 2015-07-29
JP6315841B2 (en) 2018-04-25
JP2015120755A (en) 2015-07-02
PT2321012T (en) 2019-01-11
EP2321012B1 (en) 2018-10-10
MX2011001800A (en) 2011-04-04
JP5976036B2 (en) 2016-08-23
US11324713B2 (en) 2022-05-10
KR20110058818A (en) 2011-06-01
JP2014148552A (en) 2014-08-21
RU2534606C2 (en) 2014-11-27
RU2011110392A (en) 2012-09-27
EP2321012A4 (en) 2011-10-05

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