CA2734650A1 - Organoarsenic compounds and methods for the treatment of cancer - Google Patents

Organoarsenic compounds and methods for the treatment of cancer Download PDF

Info

Publication number
CA2734650A1
CA2734650A1 CA2734650A CA2734650A CA2734650A1 CA 2734650 A1 CA2734650 A1 CA 2734650A1 CA 2734650 A CA2734650 A CA 2734650A CA 2734650 A CA2734650 A CA 2734650A CA 2734650 A1 CA2734650 A1 CA 2734650A1
Authority
CA
Canada
Prior art keywords
lymphoma
compound
hodgkin
10alkyl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2734650A
Other languages
English (en)
French (fr)
Inventor
Brian Eric Schwartz
Jonathan Lewis
Philip B. Komarnitsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ziopharm Oncology Inc
Original Assignee
Ziopharm Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ziopharm Oncology Inc filed Critical Ziopharm Oncology Inc
Publication of CA2734650A1 publication Critical patent/CA2734650A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/285—Arsenic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2734650A 2008-08-20 2009-08-14 Organoarsenic compounds and methods for the treatment of cancer Abandoned CA2734650A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18951108P 2008-08-20 2008-08-20
US61/189,511 2008-08-20
PCT/US2009/053858 WO2010021928A1 (en) 2008-08-20 2009-08-14 Organoarsenic compounds and methods for the treatment of cancer

Publications (1)

Publication Number Publication Date
CA2734650A1 true CA2734650A1 (en) 2010-02-25

Family

ID=41707414

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2734650A Abandoned CA2734650A1 (en) 2008-08-20 2009-08-14 Organoarsenic compounds and methods for the treatment of cancer

Country Status (19)

Country Link
US (4) US20110269697A1 (enExample)
EP (2) EP3388111B1 (enExample)
JP (5) JP5933896B2 (enExample)
KR (3) KR20180103194A (enExample)
CN (2) CN104800828A (enExample)
AU (1) AU2009282972A1 (enExample)
BR (1) BRPI0918407A2 (enExample)
CA (1) CA2734650A1 (enExample)
DK (2) DK3388111T3 (enExample)
ES (2) ES2901426T3 (enExample)
HK (1) HK1212218A1 (enExample)
IL (1) IL211153A0 (enExample)
MX (1) MX2011001800A (enExample)
NZ (1) NZ591181A (enExample)
PT (2) PT2321012T (enExample)
RU (1) RU2534606C2 (enExample)
SG (3) SG10201810449XA (enExample)
WO (1) WO2010021928A1 (enExample)
ZA (1) ZA201101216B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11998654B2 (en) 2018-07-12 2024-06-04 Bard Shannon Limited Securing implants and medical devices

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI617305B (zh) * 2013-12-05 2018-03-11 蘇愛康制藥有限公司 治療癌症的化合物及其應用程序
CN104151397A (zh) * 2014-07-03 2014-11-19 北京大学 一类新型三硫杂二环有机砷化物及其合成方法和在抗肿瘤领域里的应用
JP6413969B2 (ja) * 2015-07-29 2018-10-31 住友金属鉱山株式会社 日射遮蔽体形成用分散液および当該分散液を用いた日射遮蔽体
JPWO2019220961A1 (ja) * 2018-05-18 2020-05-28 ソレイジア・ファーマ株式会社 ダリナパルシンのアルカリ金属塩及び/又は無機酸付加塩の結晶型及びその製剤
CN113408945B (zh) * 2021-07-15 2023-03-24 广西中烟工业有限责任公司 一种烤烟纯度的检测方法、装置、电子设备及存储介质

Family Cites Families (19)

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US234972A (en) 1880-11-30 William ennis
US761900A (en) 1904-03-05 1904-06-07 Newton Jefferson Norman Flux compound.
US2349729A (en) 1940-08-24 1944-05-23 Parke Davis & Co Therapeutic arsenic preparation
EP1391206B1 (en) 1997-10-15 2008-07-02 Polarx Biopharmaceuticals, Inc. Pharmaceutical compositions comprising arsenic trioxide for the treatment of non-Hodgkin's lymphoma
IL136051A0 (en) 1997-11-10 2001-05-20 Sloan Kettering Inst Cancer Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol
CN1233476A (zh) 1998-04-24 1999-11-03 陆道培 治疗急性白血病的药物及其制备方法
EP1002537A1 (en) 1998-10-30 2000-05-24 Assistance Publique, Hopitaux De Paris Use of melarsoprol for the manufacture of a medicament for treating B-cell lymphoproliferative diseases, such as multiple myeloma
US6191123B1 (en) 1999-03-19 2001-02-20 Parker Hughes Institute Organic-arsenic compounds
KR20030014208A (ko) 2000-04-26 2003-02-15 오레곤 헬스 사이언시즈 유니버시티 티올계 화학보호제 화합물의 투여
DE10132625A1 (de) 2001-07-05 2003-01-23 Oce Printing Systems Gmbh Verfahren, Computerprogrammprodukt und Gerätesystem zum visuellen Überprüfen von Bilddaten
JP4571408B2 (ja) 2002-01-07 2010-10-27 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム 癌治療薬としての、s−ジメチルアルシノ−チオコハク酸、s−ジメチルアルシノ−2−チオ安息香酸、s−(ジメチルアルシノ)グルタチオン
TWI411431B (zh) * 2004-07-16 2013-10-11 Texas A & M Univ Sys 有機砷化合物、其用於治療癌症之用途及包含其之醫藥組成物
ES2532666T3 (es) * 2005-07-29 2015-03-30 Solasia Pharma K.K. Compuestos y métodos para el tratamiento del cáncer
CN101395166B (zh) * 2006-01-13 2014-07-09 得克萨斯州A&M大学系统 用于治疗癌症的化合物和方法
TW200829261A (en) 2006-09-29 2008-07-16 Ziopharm Oncology Inc Method for controlling angiogenesis in animals
WO2009011893A2 (en) * 2007-07-17 2009-01-22 Combinatorx, Incorporated Treatments of b-cell proliferative disorders
EP2178370A4 (en) * 2007-07-17 2011-01-12 Zalicus Inc COMBINATIONS FOR THE TREATMENT OF PROLIFERATIVE B-CELL DISEASES
CN101903029B (zh) * 2007-11-02 2012-09-26 Zio医药肿瘤学公司 使用有机砷化物的联合治疗
WO2009151569A2 (en) * 2008-06-09 2009-12-17 Combinatorx, Incorporated Beta adrenergic receptor agonists for the treatment of b-cell proliferative disorders

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11998654B2 (en) 2018-07-12 2024-06-04 Bard Shannon Limited Securing implants and medical devices

Also Published As

Publication number Publication date
EP3388111A1 (en) 2018-10-17
RU2534606C2 (ru) 2014-11-27
PT3388111T (pt) 2021-12-23
US20210038557A1 (en) 2021-02-11
SG10201403869TA (en) 2014-10-30
ZA201101216B (en) 2011-10-26
PT2321012T (pt) 2019-01-11
ES2703740T3 (es) 2019-03-12
SG10201810449XA (en) 2018-12-28
CN104800828A (zh) 2015-07-29
SG10201810450QA (en) 2018-12-28
EP2321012B1 (en) 2018-10-10
US11324713B2 (en) 2022-05-10
EP3388111B1 (en) 2021-09-29
US10842769B2 (en) 2020-11-24
MX2011001800A (es) 2011-04-04
US20150231107A1 (en) 2015-08-20
JP2012500271A (ja) 2012-01-05
EP2321012A4 (en) 2011-10-05
ES2901426T3 (es) 2022-03-22
KR20180103194A (ko) 2018-09-18
JP2017002081A (ja) 2017-01-05
BRPI0918407A2 (pt) 2015-11-24
AU2009282972A1 (en) 2010-02-25
HK1254607A1 (en) 2019-07-26
JP5976036B2 (ja) 2016-08-23
US20110269697A1 (en) 2011-11-03
US20210038556A1 (en) 2021-02-11
JP2014148552A (ja) 2014-08-21
JP2018039853A (ja) 2018-03-15
US11324714B2 (en) 2022-05-10
EP2321012A1 (en) 2011-05-18
DK2321012T3 (en) 2018-12-03
JP6315841B2 (ja) 2018-04-25
KR20110058818A (ko) 2011-06-01
WO2010021928A1 (en) 2010-02-25
IL211153A0 (en) 2011-04-28
CN102149432A (zh) 2011-08-10
JP2015120755A (ja) 2015-07-02
RU2011110392A (ru) 2012-09-27
DK3388111T3 (da) 2021-12-06
JP5933896B2 (ja) 2016-06-15
HK1212218A1 (en) 2016-06-10
NZ591181A (en) 2012-09-28
KR20170103023A (ko) 2017-09-12

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140813

FZDE Discontinued

Effective date: 20160815