RU2527328C2 - Твердые композиции, содержащие 5-аминолевулиновую кислоту - Google Patents

Твердые композиции, содержащие 5-аминолевулиновую кислоту Download PDF

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Publication number
RU2527328C2
RU2527328C2 RU2011150920/15A RU2011150920A RU2527328C2 RU 2527328 C2 RU2527328 C2 RU 2527328C2 RU 2011150920/15 A RU2011150920/15 A RU 2011150920/15A RU 2011150920 A RU2011150920 A RU 2011150920A RU 2527328 C2 RU2527328 C2 RU 2527328C2
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solid
pharmaceutical product
ala
triglycerides
solid pharmaceutical
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RU2011150920/15A
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English (en)
Russian (ru)
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RU2011150920A (ru
Inventor
Оддвейг Селлаег ХЕЛЛАНД
Грю СТЕНСРУД
Бьорн КЛЕМ
Йон Эрик БРАЭНДЕН
Аслак ГОДАЛЬ
Йо Клавенесс
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ФотоКьюэр АСА
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2011150920/15A 2009-06-11 2010-06-11 Твердые композиции, содержащие 5-аминолевулиновую кислоту RU2527328C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09251538.6 2009-06-11
EP09251538 2009-06-11
PCT/EP2010/003531 WO2010142456A1 (en) 2009-06-11 2010-06-11 Solid compositions comprising 5-aminolevulinic acid

Publications (2)

Publication Number Publication Date
RU2011150920A RU2011150920A (ru) 2013-07-20
RU2527328C2 true RU2527328C2 (ru) 2014-08-27

Family

ID=42628133

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2011150920/15A RU2527328C2 (ru) 2009-06-11 2010-06-11 Твердые композиции, содержащие 5-аминолевулиновую кислоту

Country Status (18)

Country Link
US (1) US20120134921A1 (enExample)
EP (1) EP2440188A1 (enExample)
JP (1) JP2012529451A (enExample)
KR (1) KR20140014401A (enExample)
CN (1) CN102802612A (enExample)
AU (1) AU2010257752B2 (enExample)
BR (1) BRPI1011650A2 (enExample)
CA (1) CA2763837A1 (enExample)
CL (1) CL2011003115A1 (enExample)
CO (1) CO6480960A2 (enExample)
CR (1) CR20110649A (enExample)
MX (1) MX2011013069A (enExample)
NZ (1) NZ596946A (enExample)
PE (1) PE20120858A1 (enExample)
RU (1) RU2527328C2 (enExample)
SG (1) SG176687A1 (enExample)
WO (1) WO2010142456A1 (enExample)
ZA (1) ZA201108850B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2760132C1 (ru) * 2017-12-01 2021-11-22 ЭсБиАй ФАРМАСЬЮТИКАЛЗ КО., ЛТД. Фармацевтическая композиция для усиления противоопухолевого эффекта ингибитора иммунной контрольной точки

Families Citing this family (16)

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JP2013521251A (ja) * 2010-03-01 2013-06-10 フォトキュア エイエスエイ 美容組成物
DE102012105512A1 (de) * 2012-06-25 2014-04-24 Hennig Arzneimittel Gmbh & Co. Kg Arzneiform zur verlängerten Freisetzung von Wirkstoffen
US20140067024A1 (en) 2012-08-30 2014-03-06 Photocure Asa Dual panel photodynamic therapy lamp
GB201221123D0 (en) 2012-11-23 2013-01-09 Photocure As Device for photodynamic treatment
KR20150141958A (ko) * 2013-03-12 2015-12-21 어플라이드 바이오리서치, 인크. 개선된 약물 전달을 위한 킬레이트화 좌제
JP6588193B2 (ja) * 2014-07-31 2019-10-09 カプスゲル・ベルギウム・ナムローゼ・フェンノートシャップＣａｐｓｕｇｅｌ Ｂｅｌｇｉｕｍ ＮＶ カプセル製剤
US20170216146A1 (en) * 2014-07-31 2017-08-03 Capsugel Belgium Nv Capsule formulation
US11623008B2 (en) * 2014-08-20 2023-04-11 Professional Compounding Centers Of America Excipient compositions for mucoadhesive pharmaceutical compositions including a synergistic combination of amylopectin, pullulan, hyaluronic acid, and xyloglucan
US9956426B2 (en) 2015-02-26 2018-05-01 Amol Punjabi Upconverting nanoparticles
AU2016372575B2 (en) 2015-12-17 2022-12-08 Photocure Asa Method of photodynamic therapy (PDT) for bladder cancer
GB201522398D0 (en) 2015-12-18 2016-02-03 Photocure As Device for photodynamic therapy
CN105481946B (zh) * 2015-12-18 2019-05-21 浙江工商大学 5-氨基酮戊酸与3-羟基吡啶-4-酮的缀合物及其制备法和用途
US10744212B2 (en) 2016-03-14 2020-08-18 General Electric Company Topical application of nerve labeling dyes for image-guided surgery
GB2546128A (en) * 2016-09-28 2017-07-12 Photocure Asa Pharamaceutical compositions comprising hexaminolevulinic acid and methods of using the same
JP7136807B2 (ja) 2017-04-17 2022-09-13 ザ・ユニバーシティ・オブ・シカゴ ヒトの健康及び疾患の治療用途向けの短鎖脂肪酸の腸への送達用ポリマー材料
CN107434753A (zh) * 2017-07-26 2017-12-05 南京大学 5‑氨基乙酰丙酸及其衍生物的泡腾片及其制备方法

Citations (4)

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WO2002009690A2 (en) * 2000-07-27 2002-02-07 Photocure Asa Pharmaceutical composition comprising a photochemotherapeutic agent and a mucoadhesive agent
WO2002010120A1 (en) * 2000-07-27 2002-02-07 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US20030115388A1 (en) * 2001-11-20 2003-06-19 Carry Computer Eng., Inc. Combined flash memory drive structure
US7264629B2 (en) * 2001-11-09 2007-09-04 Qlt, Inc. Photodynamic therapy for the treatment of hair loss

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JP3181062B2 (ja) * 1991-01-31 2001-07-03 帝國製薬株式会社 下部消化管崩壊経口製剤
US6492420B2 (en) * 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CZ291132B6 (cs) * 1995-03-10 2002-12-11 Photocure Asa Estery kyselin 5-aminolevulových a farmaceutický prostředek s jejich obsahem
EP2127642A3 (en) * 1998-08-13 2010-02-24 Cima Labs, Inc. Microemulsions as solid dosage forms for oral administration
EP1184038B1 (en) * 1999-06-09 2005-12-28 Mochida Pharmaceutical Co., Ltd. System for release in lower digestive tract
DE10003620A1 (de) * 2000-01-28 2001-08-02 Asat Ag Applied Science & Tech 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
DE102005019628A1 (de) * 2005-04-26 2006-11-09 Technische Universität Braunschweig Formulierung zur dermalen Anwendung
GB0609809D0 (en) * 2006-05-17 2006-06-28 Photocure Asa Product
GB0724279D0 (en) * 2007-12-12 2008-01-23 Photocure Asa Use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002009690A2 (en) * 2000-07-27 2002-02-07 Photocure Asa Pharmaceutical composition comprising a photochemotherapeutic agent and a mucoadhesive agent
WO2002010120A1 (en) * 2000-07-27 2002-02-07 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7264629B2 (en) * 2001-11-09 2007-09-04 Qlt, Inc. Photodynamic therapy for the treatment of hair loss
US20030115388A1 (en) * 2001-11-20 2003-06-19 Carry Computer Eng., Inc. Combined flash memory drive structure

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2760132C1 (ru) * 2017-12-01 2021-11-22 ЭсБиАй ФАРМАСЬЮТИКАЛЗ КО., ЛТД. Фармацевтическая композиция для усиления противоопухолевого эффекта ингибитора иммунной контрольной точки
US11266619B2 (en) 2017-12-01 2022-03-08 Sbi Pharmaceuticals Co., Ltd. Pharmaceutical composition for enhancing antitumor effect by immune checkpoint inhibitor

Also Published As

Publication number Publication date
US20120134921A1 (en) 2012-05-31
AU2010257752B2 (en) 2015-04-09
ZA201108850B (en) 2013-02-27
RU2011150920A (ru) 2013-07-20
NZ596946A (en) 2014-07-25
EP2440188A1 (en) 2012-04-18
CN102802612A (zh) 2012-11-28
CR20110649A (es) 2012-03-22
PE20120858A1 (es) 2012-08-01
JP2012529451A (ja) 2012-11-22
AU2010257752A1 (en) 2012-01-12
CO6480960A2 (es) 2012-07-16
WO2010142456A1 (en) 2010-12-16
SG176687A1 (en) 2012-01-30
BRPI1011650A2 (pt) 2016-03-22
CA2763837A1 (en) 2010-12-16
CL2011003115A1 (es) 2012-06-22
MX2011013069A (es) 2012-02-01
KR20140014401A (ko) 2014-02-06

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20150612