RU2519655C2 - Система биосенсора для приведения в действие магнитных частиц - Google Patents

Система биосенсора для приведения в действие магнитных частиц Download PDF

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Publication number
RU2519655C2
RU2519655C2 RU2011124882/15A RU2011124882A RU2519655C2 RU 2519655 C2 RU2519655 C2 RU 2519655C2 RU 2011124882/15 A RU2011124882/15 A RU 2011124882/15A RU 2011124882 A RU2011124882 A RU 2011124882A RU 2519655 C2 RU2519655 C2 RU 2519655C2
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RU
Russia
Prior art keywords
magnetic
cartridge
biosensor
subunits
magnetic field
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RU2011124882/15A
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English (en)
Russian (ru)
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RU2011124882A (ru
Inventor
Михайло М. ОВСЯНКО
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Конинклейке Филипс Электроникс Н.В.
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
RU2011124882/15A 2008-11-19 2009-07-22 Система биосенсора для приведения в действие магнитных частиц RU2519655C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08169405 2008-11-19
EP08169405.1 2008-11-19
PCT/IB2009/053168 WO2010058303A1 (en) 2008-11-19 2009-07-22 Biosensor system for actuating magnetic particles

Publications (2)

Publication Number Publication Date
RU2011124882A RU2011124882A (ru) 2012-12-27
RU2519655C2 true RU2519655C2 (ru) 2014-06-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2011124882/15A RU2519655C2 (ru) 2008-11-19 2009-07-22 Система биосенсора для приведения в действие магнитных частиц

Country Status (6)

Country Link
US (1) US9103824B2 (ja)
EP (1) EP2368116B1 (ja)
JP (3) JP2012509491A (ja)
CN (2) CN102216780A (ja)
RU (1) RU2519655C2 (ja)
WO (1) WO2010058303A1 (ja)

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EP2720060A1 (en) * 2009-09-28 2014-04-16 Koninklijke Philips N.V. A biosensor system for single particle detection
CN103907012B (zh) * 2011-11-03 2018-02-16 皇家飞利浦有限公司 表面结合磁颗粒的检测
PT2800970T (pt) 2012-01-04 2016-12-27 Magnomics S A Dispositivo monolítico combinando cmos com sensores magnetorresistivos
EP2664914A1 (en) 2012-05-16 2013-11-20 Koninklijke Philips N.V. Magnetically assisted processing of a medium
US10485941B2 (en) 2012-11-19 2019-11-26 Koninklijke Philips N.V. System for enhancing secretion removal from an airway of a subject
JP6588908B2 (ja) 2014-06-30 2019-10-09 Ｐｈｃホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム
EP3163306A4 (en) 2014-06-30 2018-01-24 Panasonic Healthcare Holdings Co., Ltd. Substrate for sample analysis, and sample analysis apparatus
US10539582B2 (en) 2014-06-30 2020-01-21 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and method for removing liquid from liquid that contains magnetic particles
JP6588910B2 (ja) 2014-06-30 2019-10-09 Ｐｈｃホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム
US9788763B1 (en) * 2014-07-09 2017-10-17 Verily Life Sciences Llc Methods for magnetic particle capture and separation
JP6660305B2 (ja) 2014-12-12 2020-03-11 Ｐｈｃホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム
US10145906B2 (en) 2015-12-17 2018-12-04 Analog Devices Global Devices, systems and methods including magnetic structures
CN107796865B (zh) 2016-09-05 2021-05-25 财团法人工业技术研究院 生物分子磁传感器
EP3470141B1 (en) * 2017-10-11 2024-04-24 F. Hoffmann-La Roche AG Apparatus and method for processing a biological sample with magnetic particles
US10161856B1 (en) * 2018-01-19 2018-12-25 Ping-Chieh Wu Magneto-optical bio-detection devices having high sensitivity
JP7467137B2 (ja) 2020-01-28 2024-04-15 キヤノンメディカルシステムズ株式会社 検体分析装置
US11940502B2 (en) 2021-09-24 2024-03-26 Analog Devices International Unlimited Company Magnetic field sensing based on particle position within container

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US5955881A (en) * 1994-10-18 1999-09-21 Cts Corporation Linkage position sensor having a magnet with two ramped sections for providing variable magnetic field
US6136182A (en) * 1996-06-07 2000-10-24 Immunivest Corporation Magnetic devices and sample chambers for examination and manipulation of cells
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JP3266128B2 (ja) 1999-02-08 2002-03-18 日本鋼管株式会社 漏洩磁束探傷法及び漏洩磁束探傷装置
CN1181337C (zh) * 2000-08-08 2004-12-22 清华大学 微流体系统中实体分子的操纵方法及相关试剂盒
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Also Published As

Publication number Publication date
JP2015121558A (ja) 2015-07-02
EP2368116B1 (en) 2019-07-03
CN105403695A (zh) 2016-03-16
CN102216780A (zh) 2011-10-12
JP2017106927A (ja) 2017-06-15
CN105403695B (zh) 2018-08-10
US20110221427A1 (en) 2011-09-15
JP2012509491A (ja) 2012-04-19
WO2010058303A1 (en) 2010-05-27
EP2368116A1 (en) 2011-09-28
US9103824B2 (en) 2015-08-11
RU2011124882A (ru) 2012-12-27
JP6092910B2 (ja) 2017-03-08

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Effective date: 20190307