RU2506947C2 - Таблетка пролонгированного высвобождения, содержащая теобромин - Google Patents

Таблетка пролонгированного высвобождения, содержащая теобромин Download PDF

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Publication number
RU2506947C2
RU2506947C2 RU2012119070/15A RU2012119070A RU2506947C2 RU 2506947 C2 RU2506947 C2 RU 2506947C2 RU 2012119070/15 A RU2012119070/15 A RU 2012119070/15A RU 2012119070 A RU2012119070 A RU 2012119070A RU 2506947 C2 RU2506947 C2 RU 2506947C2
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RU
Russia
Prior art keywords
theobromine
release layer
sustained release
layer
release
Prior art date
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RU2012119070/15A
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English (en)
Russian (ru)
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RU2012119070A (ru
Inventor
Джин АУХ
Чан-Хван КИМ
Чан-Кюн ХАН
Хён-Гун ДЖОН
Ян-Джоон КИМ
Джон-Гиал КИМ
Джу-Ён ЁУН
Джун-Хва ЛЕЕ
Original Assignee
Ахн-Гоок Фармасьютикал Ко., Лтд.
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Publication of RU2012119070A publication Critical patent/RU2012119070A/ru
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Publication of RU2506947C2 publication Critical patent/RU2506947C2/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2012119070/15A 2009-11-02 2010-09-01 Таблетка пролонгированного высвобождения, содержащая теобромин RU2506947C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2009-0105137 2009-11-02
KR1020090105137A KR101137467B1 (ko) 2009-11-02 2009-11-02 테오브로민 함유 서방성 정제
PCT/KR2010/005911 WO2011052884A2 (ko) 2009-11-02 2010-09-01 테오브로민 함유 서방성 정제

Publications (2)

Publication Number Publication Date
RU2012119070A RU2012119070A (ru) 2013-12-10
RU2506947C2 true RU2506947C2 (ru) 2014-02-20

Family

ID=43922740

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2012119070/15A RU2506947C2 (ru) 2009-11-02 2010-09-01 Таблетка пролонгированного высвобождения, содержащая теобромин

Country Status (7)

Country Link
KR (1) KR101137467B1 (tr)
CN (1) CN102711740B (tr)
BR (1) BR112012010325B8 (tr)
RU (1) RU2506947C2 (tr)
TR (1) TR201205029T1 (tr)
UA (1) UA103558C2 (tr)
WO (1) WO2011052884A2 (tr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101220830B1 (ko) * 2010-08-18 2013-01-10 안국약품 주식회사 테오브로민의 서방성 과립제 및 그 제조방법

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060113728A (ko) * 2003-11-13 2006-11-02 룀 게엠베하 조절 물질의 전달에 영향을 미치는 매트릭스를 갖는 다층약제학적 형태
KR20070017335A (ko) * 2004-03-22 2007-02-09 노파르티스 아게 리카르바제핀을 포함하는 경구투여용 매트릭스 제제
RU2292873C2 (ru) * 2002-07-25 2007-02-10 Фармация Корпорейшн Таблетка с замедленным высвобождением, содержащая ребоксетин
KR20070078625A (ko) * 2006-01-27 2007-08-01 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법
KR20070119658A (ko) * 2005-03-29 2007-12-20 에보니크 룀 게엠베하 활성 성분 방출에 대한 조절 효과를 가지는 물질을포함하는 펠렛을 포함하는 다중 미립자 제약 형태

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2292873C2 (ru) * 2002-07-25 2007-02-10 Фармация Корпорейшн Таблетка с замедленным высвобождением, содержащая ребоксетин
KR20060113728A (ko) * 2003-11-13 2006-11-02 룀 게엠베하 조절 물질의 전달에 영향을 미치는 매트릭스를 갖는 다층약제학적 형태
KR20070017335A (ko) * 2004-03-22 2007-02-09 노파르티스 아게 리카르바제핀을 포함하는 경구투여용 매트릭스 제제
KR20070119658A (ko) * 2005-03-29 2007-12-20 에보니크 룀 게엠베하 활성 성분 방출에 대한 조절 효과를 가지는 물질을포함하는 펠렛을 포함하는 다중 미립자 제약 형태
KR20070078625A (ko) * 2006-01-27 2007-08-01 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법

Also Published As

Publication number Publication date
KR20110048367A (ko) 2011-05-11
WO2011052884A2 (ko) 2011-05-05
CN102711740A (zh) 2012-10-03
RU2012119070A (ru) 2013-12-10
TR201205029T1 (tr) 2012-09-21
WO2011052884A3 (ko) 2011-07-14
BR112012010325A2 (pt) 2016-03-29
BR112012010325B8 (pt) 2021-05-25
UA103558C2 (ru) 2013-10-25
CN102711740B (zh) 2014-02-12
BR112012010325B1 (pt) 2021-01-26
KR101137467B1 (ko) 2012-04-20

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