RU2455307C1 - Тетрациклические антибиотические производные антрахинона с высокой активностью, способ их получения и их применение - Google Patents
Тетрациклические антибиотические производные антрахинона с высокой активностью, способ их получения и их применение Download PDFInfo
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- RU2455307C1 RU2455307C1 RU2010145935/04A RU2010145935A RU2455307C1 RU 2455307 C1 RU2455307 C1 RU 2455307C1 RU 2010145935/04 A RU2010145935/04 A RU 2010145935/04A RU 2010145935 A RU2010145935 A RU 2010145935A RU 2455307 C1 RU2455307 C1 RU 2455307C1
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- RU
- Russia
- Prior art keywords
- formula
- compound represented
- group
- pyrrolyldoxorubicin
- carboxy
- Prior art date
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- 0 C*(C(*)(*)CC(O1)=O)C1=O Chemical compound C*(C(*)(*)CC(O1)=O)C1=O 0.000 description 2
- FSCGPAUHWLZCDT-TZYYWANDSA-N CC(C(C(C1)N(C(c2cccnc22)=O)C2=O)O)OC1O[C@@H](C[C@@](Cc1c(c(C(c2c3c(OC)ccc2)=O)c2C3=O)O)(C(CO)=O)O)c1c2O Chemical compound CC(C(C(C1)N(C(c2cccnc22)=O)C2=O)O)OC1O[C@@H](C[C@@](Cc1c(c(C(c2c3c(OC)ccc2)=O)c2C3=O)O)(C(CO)=O)O)c1c2O FSCGPAUHWLZCDT-TZYYWANDSA-N 0.000 description 1
- YUZKWSWDBCAHMI-ZYZADVEISA-N CC(C(C(C1)N(CCC2)C2=O)O)OC1O[C@@H](C[C@@](Cc1c(c(C(c2cccc(OC)c22)=O)c3C2=O)O)(C(CO)=O)O)c1c3O Chemical compound CC(C(C(C1)N(CCC2)C2=O)O)OC1O[C@@H](C[C@@](Cc1c(c(C(c2cccc(OC)c22)=O)c3C2=O)O)(C(CO)=O)O)c1c3O YUZKWSWDBCAHMI-ZYZADVEISA-N 0.000 description 1
- VRHDGKFRYJRPLE-JVVPJMNLSA-N CC(C(C(C1)[n]2cccc2)O)OC1O[C@@H](C[C@@](Cc1c(c(C(c2cccc(OC)c22)=O)c3C2=N)O)(C(C)=O)O)c1c3O Chemical compound CC(C(C(C1)[n]2cccc2)O)OC1O[C@@H](C[C@@](Cc1c(c(C(c2cccc(OC)c22)=O)c3C2=N)O)(C(C)=O)O)c1c3O VRHDGKFRYJRPLE-JVVPJMNLSA-N 0.000 description 1
- LAGBBEMCWAIAAX-VGZMTVPCSA-N CC(C(C(C1)[n]2cccc2)O)OC1O[C@@H](C[C@@](Cc1c(c(C(c2cccc(OC)c22)=O)c3C2=O)O)(C(C)=O)O)c1c3O Chemical compound CC(C(C(C1)[n]2cccc2)O)OC1O[C@@H](C[C@@](Cc1c(c(C(c2cccc(OC)c22)=O)c3C2=O)O)(C(C)=O)O)c1c3O LAGBBEMCWAIAAX-VGZMTVPCSA-N 0.000 description 1
- ISHIKFJBMQTRBJ-DCNYUSHISA-N CC(C(C(C1)[n]2cccc2)O)OC1[O]([C@@H](C[C@@](Cc1c(c(C(c2c3cccc2)=O)c2C3=O)O)(C(C)=O)[O]#C)c1c2O)#C Chemical compound CC(C(C(C1)[n]2cccc2)O)OC1[O]([C@@H](C[C@@](Cc1c(c(C(c2c3cccc2)=O)c2C3=O)O)(C(C)=O)[O]#C)c1c2O)#C ISHIKFJBMQTRBJ-DCNYUSHISA-N 0.000 description 1
- CDUVOMZNLOUHFA-RIURQHHGSA-N CC(C(C(C1)[n]2cccc2)OC2OCCCC2)OC1O[C@@H](C[C@@](Cc1c(c(C(c2cccc(OC)c22)=O)c3C2=O)O)(C(COC(CCC(O)=O)=O)=O)O)c1c3O Chemical compound CC(C(C(C1)[n]2cccc2)OC2OCCCC2)OC1O[C@@H](C[C@@](Cc1c(c(C(c2cccc(OC)c22)=O)c3C2=O)O)(C(COC(CCC(O)=O)=O)=O)O)c1c3O CDUVOMZNLOUHFA-RIURQHHGSA-N 0.000 description 1
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- Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810052710 | 2008-04-11 | ||
| CN200810052710.3 | 2008-04-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2010145935A RU2010145935A (ru) | 2012-05-20 |
| RU2455307C1 true RU2455307C1 (ru) | 2012-07-10 |
Family
ID=43510098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2010145935/04A RU2455307C1 (ru) | 2008-04-11 | 2009-04-09 | Тетрациклические антибиотические производные антрахинона с высокой активностью, способ их получения и их применение |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JP5647971B2 (ja) |
| KR (1) | KR101328315B1 (ja) |
| BR (1) | BRPI0911647A2 (ja) |
| ES (1) | ES2655243T3 (ja) |
| MX (1) | MX2010011079A (ja) |
| RU (1) | RU2455307C1 (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014059740A1 (zh) | 2012-03-06 | 2014-04-24 | 天津和美生物技术有限公司 | 四环蒽醌衍生物 |
| JP6327418B2 (ja) | 2014-09-04 | 2018-05-23 | Smc株式会社 | デュアル４ポート電磁弁 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2296495A (en) * | 1994-12-23 | 1996-07-03 | Erba Carlo Spa | Morpholine and piperidine N-oxide based anthracycline derivatives as antitumour agents |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9418260D0 (en) * | 1994-09-09 | 1994-10-26 | Erba Carlo Spa | Anthracycline derivatives |
| US5843903A (en) * | 1995-11-27 | 1998-12-01 | The Administrators Of The Tulane Educational Fund | Targeted cytotoxic anthracycline analogs |
| GB2315067B (en) * | 1996-07-11 | 2000-02-16 | Pharmacia Spa | Morpholinyl anthracycline derivatives |
| CA2519310A1 (en) | 2003-03-18 | 2004-09-30 | Maria Adele Pacciarini | Combined therapy comprising nemorubicin and a cyclooxygenase-2-inhibitor |
-
2009
- 2009-04-09 JP JP2011503328A patent/JP5647971B2/ja active Active
- 2009-04-09 KR KR1020107024303A patent/KR101328315B1/ko active IP Right Grant
- 2009-04-09 MX MX2010011079A patent/MX2010011079A/es not_active Application Discontinuation
- 2009-04-09 ES ES09731373.8T patent/ES2655243T3/es active Active
- 2009-04-09 BR BRPI0911647A patent/BRPI0911647A2/pt not_active IP Right Cessation
- 2009-04-09 RU RU2010145935/04A patent/RU2455307C1/ru not_active IP Right Cessation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2296495A (en) * | 1994-12-23 | 1996-07-03 | Erba Carlo Spa | Morpholine and piperidine N-oxide based anthracycline derivatives as antitumour agents |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2655243T3 (es) | 2018-02-19 |
| MX2010011079A (es) | 2012-06-01 |
| RU2010145935A (ru) | 2012-05-20 |
| KR101328315B1 (ko) | 2013-11-11 |
| JP5647971B2 (ja) | 2015-01-07 |
| BRPI0911647A2 (pt) | 2015-10-13 |
| JP2011516507A (ja) | 2011-05-26 |
| KR20100135859A (ko) | 2010-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC41 | Official registration of the transfer of exclusive right |
Effective date: 20170718 |
|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20210410 |