RU2436590C1 - Применение альфа-1-антитрипсина для получения лекарственных средств для лечения синдрома хронической усталости - Google Patents

Применение альфа-1-антитрипсина для получения лекарственных средств для лечения синдрома хронической усталости Download PDF

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Publication number
RU2436590C1
RU2436590C1 RU2010126653/15A RU2010126653A RU2436590C1 RU 2436590 C1 RU2436590 C1 RU 2436590C1 RU 2010126653/15 A RU2010126653/15 A RU 2010126653/15A RU 2010126653 A RU2010126653 A RU 2010126653A RU 2436590 C1 RU2436590 C1 RU 2436590C1
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Russia
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aat
cfs
alpha
antitrypsin
patients
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RU2010126653/15A
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English (en)
Russian (ru)
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КИНТАНА Ана ГАРСИЯ (ES)
КИНТАНА Ана ГАРСИЯ
МАРТИН Хосе АЛЕГРЕ (ES)
МАРТИН Хосе АЛЕГРЕ
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Грифольс, С.А.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4826Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/56Protease inhibitors from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
RU2010126653/15A 2009-06-30 2010-06-29 Применение альфа-1-антитрипсина для получения лекарственных средств для лечения синдрома хронической усталости RU2436590C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200930387 2009-06-30
ES200930387A ES2332645B1 (es) 2009-06-30 2009-06-30 Utilizacion de alfa-1-antitripsina para la preparacion de medicamentos para el tratamiento del sindrome de fatiga cronica.

Publications (1)

Publication Number Publication Date
RU2436590C1 true RU2436590C1 (ru) 2011-12-20

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RU2010126653/15A RU2436590C1 (ru) 2009-06-30 2010-06-29 Применение альфа-1-антитрипсина для получения лекарственных средств для лечения синдрома хронической усталости

Country Status (16)

Country Link
US (1) US9205134B2 (https=)
EP (1) EP2289540B1 (https=)
JP (1) JP5231490B2 (https=)
CN (1) CN101934071B (https=)
AR (1) AR077123A1 (https=)
AU (1) AU2010202203B2 (https=)
BR (1) BRPI1002087B1 (https=)
CA (1) CA2706212C (https=)
CL (1) CL2010000575A1 (https=)
ES (2) ES2332645B1 (https=)
MX (1) MX2010006125A (https=)
NZ (1) NZ585890A (https=)
PL (1) PL2289540T3 (https=)
PT (1) PT2289540E (https=)
RU (1) RU2436590C1 (https=)
UY (1) UY32670A (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2840475C2 (ru) * 2021-05-03 2025-05-26 Ажероникс Са Альфа-1-антитрипсин (ААТ) в лечении и (или) профилактике неврологических нарушений

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014014751A8 (pt) * 2011-12-19 2017-07-04 Lfb Usa Inc composição compreendendo alfa-1-antitripsina, células epiteliais de glândula mamária, mamífero não humano transgênico, e, método para reduzir a atividade de elastase no pulmão
US10034921B2 (en) 2013-02-13 2018-07-31 Laboratoire Français Du Fractionnement Et Des Biotechnologies Proteins with modified glycosylation and methods of production thereof
US20220160847A1 (en) * 2020-11-20 2022-05-26 Mark Egly Method of preventing and/or treating a plurality of diseases
WO2023184473A1 (zh) * 2022-04-01 2023-10-05 首创生物技术有限公司 肽用于治疗神经退行性疾病或改善认知功能的用途

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992020327A1 (en) * 1991-05-14 1992-11-26 Ernir Snorrason Treatment of fatigue syndrome with cholinesterase inhibitors
WO1998005350A1 (en) * 1996-08-08 1998-02-12 Milkhaus Laboratory, Inc. Materials and methods for treatment of plaquing diseases
WO2000051623A2 (en) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions
WO2008143633A2 (en) * 2007-01-10 2008-11-27 University Of Florida Compounds and methods for treatment of alpha-1 antitrypsin deficiency
US7459532B2 (en) * 2003-05-12 2008-12-02 Bristol-Myers Squibb Company Variants of the TRP channel family member, LTRPC3G

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2281222A (en) * 1941-09-27 1942-04-28 American Bosch Corp Speed regulator for internal combustion engines
WO2001081343A2 (en) * 2000-04-21 2001-11-01 Pharmacia & Upjohn Company Compounds for treating fibromyalgia and chronic fatigue syndrome
WO2002006837A1 (en) * 2000-07-14 2002-01-24 Matsushita Electric Industrial Co., Ltd. Particle-labeled protein and immuno-chromatograph using the same
AU2003286258B2 (en) 2002-11-20 2006-12-21 Arriva-Prometic Inc. Composition and method for treating inflammatory diseases using protease inhibitors
US7850970B2 (en) * 2003-08-26 2010-12-14 The Regents Of The University Of Colorado Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections
WO2006026837A1 (en) * 2004-09-07 2006-03-16 Patrick Englebienne Diagnostic methods for measuring elastase activity levels
ES2281222B1 (es) 2004-09-24 2008-06-01 Grifols, S.A. Utilizacion de alfa-1 antitripsina para la preparacion de medicamentos para el tratamiento de la fibromialgia.
MX2010003113A (es) * 2007-09-25 2010-04-01 Abbott Lab Compuestos de octahidropentaleno como antagonistas del receptor de quimiocina.
HUE030205T2 (en) 2007-11-02 2017-05-29 Grifols Therapeutics Inc A method, composition, and product for providing alpha-1-antitrypsin

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992020327A1 (en) * 1991-05-14 1992-11-26 Ernir Snorrason Treatment of fatigue syndrome with cholinesterase inhibitors
WO1998005350A1 (en) * 1996-08-08 1998-02-12 Milkhaus Laboratory, Inc. Materials and methods for treatment of plaquing diseases
WO2000051623A2 (en) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions
US7459532B2 (en) * 2003-05-12 2008-12-02 Bristol-Myers Squibb Company Variants of the TRP channel family member, LTRPC3G
WO2008143633A2 (en) * 2007-01-10 2008-11-27 University Of Florida Compounds and methods for treatment of alpha-1 antitrypsin deficiency

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Alpha 1-Antitrypsin RN: 9041-92-3 [онлайн] [найдено 2011-04-04] (Найдено из базы данных ChemlDplus). Fregonese L. et al. Hereditary alpha-1-antitrvpsin deficiency and its clinical consequences. Orphanet J Rare Dis. 2008 Jun 19;3:16. [онлайн] [найдено 2011-04-04] Найдено из базы данных PubMed PMID: 18565211. Schmechel DE et al. Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders. Neurotoxicology. 2006 Sep; 27(5):637-57. Реферат [онлайн] [найдено 2011-04-05] Найдено из базы данных PubMed PMID: 16870258. Wachter AM et al. Treatment of atopic dermatitis with alpha 1-proteinase inhibitor. Ann Allergy. 1992 Nov; 69(5):407-14. Реферат [онлайн] [найдено 2011-04-05] Найдено из базы данных PubMed PMID: 1456482. Torpy DJ et al. Familial corticosteroid-binding globulin deficiency due to a novel null mutation: association with fatigue and relative hypotension. J Clin Endocrinol Metab. 2001 Aug; 86(8):3692-700. [онлайн] [найдено 2011-04-04] Найдено из базы дан *
Малашенкова И.К. и др. Синдром хронической усталости // Русский медицинский журнал от 17 июня 1997 г., т.5, №12 [онлайн] [найдено 2011-04-05] Найдено из базы данных YANDEX. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2840475C2 (ru) * 2021-05-03 2025-05-26 Ажероникс Са Альфа-1-антитрипсин (ААТ) в лечении и (или) профилактике неврологических нарушений

Also Published As

Publication number Publication date
NZ585890A (en) 2011-11-25
AR077123A1 (es) 2011-08-03
AU2010202203A1 (en) 2011-01-20
CL2010000575A1 (es) 2011-10-28
US9205134B2 (en) 2015-12-08
US20100331261A1 (en) 2010-12-30
CA2706212C (en) 2014-02-04
BRPI1002087A2 (pt) 2012-03-13
EP2289540B1 (en) 2012-08-22
AU2010202203B2 (en) 2012-08-23
EP2289540A1 (en) 2011-03-02
MX2010006125A (es) 2011-01-05
ES2332645B1 (es) 2010-10-18
PL2289540T3 (pl) 2013-03-29
ES2392691T3 (es) 2012-12-12
CN101934071B (zh) 2012-11-28
CN101934071A (zh) 2011-01-05
JP2011012060A (ja) 2011-01-20
UY32670A (es) 2011-01-31
BRPI1002087B1 (pt) 2019-07-02
CA2706212A1 (en) 2010-12-30
HK1148198A1 (en) 2011-09-02
PT2289540E (pt) 2012-12-04
JP5231490B2 (ja) 2013-07-10
ES2332645A1 (es) 2010-02-09

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