ES2332645B1 - Utilizacion de alfa-1-antitripsina para la preparacion de medicamentos para el tratamiento del sindrome de fatiga cronica. - Google Patents
Utilizacion de alfa-1-antitripsina para la preparacion de medicamentos para el tratamiento del sindrome de fatiga cronica.Info
- Publication number
- ES2332645B1 ES2332645B1 ES200930387A ES200930387A ES2332645B1 ES 2332645 B1 ES2332645 B1 ES 2332645B1 ES 200930387 A ES200930387 A ES 200930387A ES 200930387 A ES200930387 A ES 200930387A ES 2332645 B1 ES2332645 B1 ES 2332645B1
- Authority
- ES
- Spain
- Prior art keywords
- aat
- cfs
- antitrypsin
- alpha
- chronic fatigue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/56—Protease inhibitors from plants
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
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- Toxicology (AREA)
- Nutrition Science (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
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| PT103800710T PT2289540E (pt) | 2009-06-30 | 2010-05-20 | Alfa-1-antitripsina para usar no tratamento de síndrome de fadiga crónica |
| EP10380071A EP2289540B1 (en) | 2009-06-30 | 2010-05-20 | Alpha-1-antitrypsin for use in the treatment of chronic fatigue syndrome |
| ES10380071T ES2392691T3 (es) | 2009-06-30 | 2010-05-20 | ALFA-1-ANTITRIPSINA para utilización en el tratamiento del sindrome de fatiga crónica |
| PL10380071T PL2289540T3 (pl) | 2009-06-30 | 2010-05-20 | Alfa-1-antytrypsyna do stosowania w leczeniu zespołu chronicznego zmęczenia |
| UY0001032670A UY32670A (es) | 2009-06-30 | 2010-05-27 | Utilizacion de alfa -1-antitripisina para la preparacion de medicamentos para el tratamiento del sindrome de fatiga cronica |
| AU2010202203A AU2010202203B2 (en) | 2009-06-30 | 2010-05-28 | Use of alpha-1- antitrypsin for the preparation of drugs for the treatment of chronic fatigue syndrome |
| CL2010000575A CL2010000575A1 (es) | 2009-06-30 | 2010-06-02 | Uso de alfa-1 antitripsina o sus derivados para el tratamiento del sindrome de fatiga cronica, donde dicha antitripsina es purificada del plasma humano o es producida por tecnologia transgenica o recombinante. |
| NZ585890A NZ585890A (en) | 2009-06-30 | 2010-06-02 | Use of alpha-1-antitrypsin for the prepration of drugs for the treatment of chronic fatigue syndrome |
| MX2010006125A MX2010006125A (es) | 2009-06-30 | 2010-06-03 | Utilizacion de alfa-1-antitripsina para la preparacion de medicamentos para el tratamiento del sindrome de fatiga cronica. |
| CA2706212A CA2706212C (en) | 2009-06-30 | 2010-06-04 | Use of alpha-1-antitrypsin for the preparation of drugs for the treatment of chronic fatigue syndrome |
| ARP100102142A AR077123A1 (es) | 2009-06-30 | 2010-06-17 | Utilizacion de alfa-1-antitripsina para la preparacion de medicamentos para el tratamiento del sindrome de fatiga cronica |
| US12/822,764 US9205134B2 (en) | 2009-06-30 | 2010-06-24 | Use of alpha-1-antitrypsin for the preparation of drugs for the treatment of chronic fatigue syndrome |
| BRPI1002087-0A BRPI1002087B1 (pt) | 2009-06-30 | 2010-06-24 | Uso de alfa-1-antitripsina para a preparação de medicamentos para o tratamento da síndrome da fadiga crônica |
| JP2010147994A JP5231490B2 (ja) | 2009-06-30 | 2010-06-29 | 慢性疲労症候群の治療用の医薬の製造のための、アルファ−１−アンチトリプシンの使用 |
| RU2010126653/15A RU2436590C1 (ru) | 2009-06-30 | 2010-06-29 | Применение альфа-1-антитрипсина для получения лекарственных средств для лечения синдрома хронической усталости |
| CN2010102168418A CN101934071B (zh) | 2009-06-30 | 2010-06-30 | α-1-抗胰蛋白酶在制备用于治疗慢性疲劳综合症的药物中的用途 |
| HK11102279.5A HK1148198B (en) | 2009-06-30 | 2011-03-07 | Use of alpha-1-antitrypsin for the preparation of drugs for the treatment of chronic fatigue syndrome |
Applications Claiming Priority (1)
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| ES200930387A ES2332645B1 (es) | 2009-06-30 | 2009-06-30 | Utilizacion de alfa-1-antitripsina para la preparacion de medicamentos para el tratamiento del sindrome de fatiga cronica. |
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| ES10380071T Active ES2392691T3 (es) | 2009-06-30 | 2010-05-20 | ALFA-1-ANTITRIPSINA para utilización en el tratamiento del sindrome de fatiga crónica |
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| BR112014014751A8 (pt) * | 2011-12-19 | 2017-07-04 | Lfb Usa Inc | composição compreendendo alfa-1-antitripsina, células epiteliais de glândula mamária, mamífero não humano transgênico, e, método para reduzir a atividade de elastase no pulmão |
| US10034921B2 (en) | 2013-02-13 | 2018-07-31 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
| US20220160847A1 (en) * | 2020-11-20 | 2022-05-26 | Mark Egly | Method of preventing and/or treating a plurality of diseases |
| WO2023184473A1 (zh) * | 2022-04-01 | 2023-10-05 | 首创生物技术有限公司 | 肽用于治疗神经退行性疾病或改善认知功能的用途 |
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| ES2281222A1 (es) * | 2004-09-24 | 2007-09-16 | Grifols, S.A. | Utilizacion de alfa-1 antitripsina para la preparacion de medicamentos para el tratamiento de la fibromialgia. |
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| US2281222A (en) * | 1941-09-27 | 1942-04-28 | American Bosch Corp | Speed regulator for internal combustion engines |
| US5753624A (en) * | 1990-04-27 | 1998-05-19 | Milkhaus Laboratory, Inc. | Materials and methods for treatment of plaquing disease |
| EP0584185B1 (en) * | 1991-05-14 | 1999-08-11 | Ernir Snorrason | Treatment of fatigue syndrome with cholinesterase inhibitors |
| WO2000051623A2 (en) | 1999-03-05 | 2000-09-08 | The Trustees Of University Technology Corporation | Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions |
| WO2001081343A2 (en) * | 2000-04-21 | 2001-11-01 | Pharmacia & Upjohn Company | Compounds for treating fibromyalgia and chronic fatigue syndrome |
| WO2002006837A1 (en) * | 2000-07-14 | 2002-01-24 | Matsushita Electric Industrial Co., Ltd. | Particle-labeled protein and immuno-chromatograph using the same |
| AU2003286258B2 (en) | 2002-11-20 | 2006-12-21 | Arriva-Prometic Inc. | Composition and method for treating inflammatory diseases using protease inhibitors |
| US7344882B2 (en) * | 2003-05-12 | 2008-03-18 | Bristol-Myers Squibb Company | Polynucleotides encoding variants of the TRP channel family member, LTRPC3 |
| US7850970B2 (en) * | 2003-08-26 | 2010-12-14 | The Regents Of The University Of Colorado | Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections |
| WO2006026837A1 (en) * | 2004-09-07 | 2006-03-16 | Patrick Englebienne | Diagnostic methods for measuring elastase activity levels |
| EP2114141A2 (en) * | 2007-01-10 | 2009-11-11 | University of Florida | Compounds and methods for treatment of alpha-1 antitrypsin deficiency |
| MX2010003113A (es) * | 2007-09-25 | 2010-04-01 | Abbott Lab | Compuestos de octahidropentaleno como antagonistas del receptor de quimiocina. |
| HUE030205T2 (en) | 2007-11-02 | 2017-05-29 | Grifols Therapeutics Inc | A method, composition, and product for providing alpha-1-antitrypsin |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2281222A1 (es) * | 2004-09-24 | 2007-09-16 | Grifols, S.A. | Utilizacion de alfa-1 antitripsina para la preparacion de medicamentos para el tratamiento de la fibromialgia. |
Non-Patent Citations (3)
| Title |
|---|
| L.H. LUND-OLESEN, K. LUND-OLESEN "{}The etiology and possible treatment of chronic fatigue syndrome/fibromyalgia"{} Medical hypotheses 1994, Vol. 43, páginas 55-58. * |
| TIMOTHY CRAIG, SUJANI KAKUMANU "{}Chronic fatigue syndrome: evaluation and treatment"{} American family physician. 2002, Vol. 15, páginas 1083-1090. * |
| W. TARELLO "{}Chronic fatigue syndrome (CFS) associated with staphylococcus spp. bacteremia, responsive to potassium arsenite 0,5% in a veterinary surgeon and his coworking wife, handling with CFS animal cases"{} Comparative immunology, microbiology & infectious diseases. 2001, Vol. 24, páginas 233-246. * |
Also Published As
| Publication number | Publication date |
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| NZ585890A (en) | 2011-11-25 |
| AR077123A1 (es) | 2011-08-03 |
| AU2010202203A1 (en) | 2011-01-20 |
| CL2010000575A1 (es) | 2011-10-28 |
| US9205134B2 (en) | 2015-12-08 |
| US20100331261A1 (en) | 2010-12-30 |
| CA2706212C (en) | 2014-02-04 |
| BRPI1002087A2 (pt) | 2012-03-13 |
| EP2289540B1 (en) | 2012-08-22 |
| AU2010202203B2 (en) | 2012-08-23 |
| EP2289540A1 (en) | 2011-03-02 |
| MX2010006125A (es) | 2011-01-05 |
| PL2289540T3 (pl) | 2013-03-29 |
| ES2392691T3 (es) | 2012-12-12 |
| CN101934071B (zh) | 2012-11-28 |
| CN101934071A (zh) | 2011-01-05 |
| JP2011012060A (ja) | 2011-01-20 |
| UY32670A (es) | 2011-01-31 |
| BRPI1002087B1 (pt) | 2019-07-02 |
| CA2706212A1 (en) | 2010-12-30 |
| RU2436590C1 (ru) | 2011-12-20 |
| HK1148198A1 (en) | 2011-09-02 |
| PT2289540E (pt) | 2012-12-04 |
| JP5231490B2 (ja) | 2013-07-10 |
| ES2332645A1 (es) | 2010-02-09 |
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