RU2436568C2 - Самоконсервирующиеся водные фармацевтические композиции - Google Patents

Самоконсервирующиеся водные фармацевтические композиции Download PDF

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Publication number
RU2436568C2
RU2436568C2 RU2009114849/15A RU2009114849A RU2436568C2 RU 2436568 C2 RU2436568 C2 RU 2436568C2 RU 2009114849/15 A RU2009114849/15 A RU 2009114849/15A RU 2009114849 A RU2009114849 A RU 2009114849A RU 2436568 C2 RU2436568 C2 RU 2436568C2
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Russia
Prior art keywords
composition
concentration
days
compositions
polyol
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RU2009114849/15A
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English (en)
Russian (ru)
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RU2009114849A (ru
Inventor
Бхагвати П. КАБРА (US)
Бхагвати П. КАБРА
Масуд А. ЧОВХАН (US)
Масуд А. ЧОВХАН
Л. Уэйн ШНЕЙДЕР (US)
Л. Уэйн ШНЕЙДЕР
Уэсли Вехсин ХАН (US)
Уэсли Вехсин ХАН
Original Assignee
Алькон Рисерч, Лтд.
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Application filed by Алькон Рисерч, Лтд. filed Critical Алькон Рисерч, Лтд.
Publication of RU2009114849A publication Critical patent/RU2009114849A/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/22—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
RU2009114849/15A 2006-09-21 2007-09-20 Самоконсервирующиеся водные фармацевтические композиции RU2436568C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US82652906P 2006-09-21 2006-09-21
US60/826,529 2006-09-21
US82741106P 2006-09-28 2006-09-28
US60/827,411 2006-09-28

Publications (2)

Publication Number Publication Date
RU2009114849A RU2009114849A (ru) 2010-10-27
RU2436568C2 true RU2436568C2 (ru) 2011-12-20

Family

ID=39156274

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009114849/15A RU2436568C2 (ru) 2006-09-21 2007-09-20 Самоконсервирующиеся водные фармацевтические композиции

Country Status (21)

Country Link
US (3) US8268299B2 (enExample)
EP (1) EP2068822B2 (enExample)
JP (2) JP4785970B2 (enExample)
KR (1) KR101021933B1 (enExample)
AR (1) AR062929A1 (enExample)
AT (1) ATE531358T1 (enExample)
AU (1) AU2007299727B2 (enExample)
BR (1) BRPI0717067A2 (enExample)
CA (1) CA2606370C (enExample)
CL (1) CL2007002705A1 (enExample)
CY (1) CY1112138T1 (enExample)
DK (1) DK2068822T4 (enExample)
ES (1) ES2374444T5 (enExample)
MX (1) MX2009002221A (enExample)
PL (1) PL2068822T5 (enExample)
PT (1) PT2068822E (enExample)
RU (1) RU2436568C2 (enExample)
SI (1) SI2068822T2 (enExample)
TW (1) TWI394564B (enExample)
UY (1) UY30605A1 (enExample)
WO (1) WO2008036847A2 (enExample)

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PL2066300T5 (pl) 2006-09-28 2020-03-31 Novartis Ag Samokonserwujące wodne kompozycje farmaceutyczne
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US11458041B2 (en) 2015-10-08 2022-10-04 Ocular Therapeutix, Inc. Punctal plug and bioadhesives
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WO2019123266A1 (en) 2017-12-20 2019-06-27 Novartis Ag Ophthalmic composition having a prostaglandin and a beta-blocker
DK3861985T3 (da) 2020-02-06 2023-07-24 Ocular Therapeutix Inc Sammensætninger og fremgangsmåder til behandling af øjensygdomme
CA3177005A1 (en) 2020-04-27 2021-11-04 Michael Goldstein Methods of treating allergic conjunctivitis
US20220031739A1 (en) * 2020-07-31 2022-02-03 Eye Therapies Llc Anti-viral compositions and methods of use thereof
WO2023054669A1 (ja) 2021-09-30 2023-04-06 ロート製薬株式会社 眼科組成物
EP4543456A1 (en) * 2022-06-27 2025-04-30 Zaklady Farmaceutyczne "Polpharma" Spolka Akcyjna Preservative-free ophthalmic composition comprising a prostaglandin analogue
US20250381275A1 (en) 2022-07-06 2025-12-18 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition
EP4309644A1 (en) * 2022-07-22 2024-01-24 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Preservative-free ophthalmic composition comprising an antiglaucoma agent

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US20020098160A1 (en) * 1992-05-06 2002-07-25 Masood Chowhan Use of borate-polyol complexes in ophthalmic compositions
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Also Published As

Publication number Publication date
SI2068822T2 (sl) 2022-10-28
SI2068822T1 (sl) 2012-02-29
EP2068822B1 (en) 2011-11-02
WO2008036847A3 (en) 2008-05-29
CA2606370A1 (en) 2008-03-21
RU2009114849A (ru) 2010-10-27
TW200820962A (en) 2008-05-16
WO2008036847A2 (en) 2008-03-27
CA2606370C (en) 2012-03-27
AU2007299727A1 (en) 2008-03-27
AR062929A1 (es) 2008-12-17
PL2068822T3 (pl) 2012-03-30
ES2374444T5 (es) 2022-11-21
DK2068822T4 (da) 2022-10-31
JP4785970B2 (ja) 2011-10-05
CY1112138T1 (el) 2015-11-04
PT2068822E (pt) 2012-01-10
BRPI0717067A2 (pt) 2013-09-24
DK2068822T3 (da) 2012-01-23
PL2068822T5 (pl) 2022-11-14
CL2007002705A1 (es) 2008-05-16
US8268299B2 (en) 2012-09-18
UY30605A1 (es) 2008-03-31
US8323630B2 (en) 2012-12-04
ES2374444T3 (es) 2012-02-16
JP5411897B2 (ja) 2014-02-12
AU2007299727A8 (en) 2009-04-09
US20110195132A1 (en) 2011-08-11
TWI394564B (zh) 2013-05-01
EP2068822A2 (en) 2009-06-17
ATE531358T1 (de) 2011-11-15
HK1126667A1 (en) 2009-09-11
KR101021933B1 (ko) 2011-03-16
JP2010504358A (ja) 2010-02-12
EP2068822B2 (en) 2022-07-27
JP2011246476A (ja) 2011-12-08
MX2009002221A (es) 2009-03-13
AU2007299727B2 (en) 2011-10-06
US20080075790A1 (en) 2008-03-27
US20130053440A1 (en) 2013-02-28
KR20090058567A (ko) 2009-06-09

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