RU2427586C2 - Мотивы семейства панкреатических полипептидов, полипептиды и способы их использования - Google Patents
Мотивы семейства панкреатических полипептидов, полипептиды и способы их использования Download PDFInfo
- Publication number
- RU2427586C2 RU2427586C2 RU2007126653/04A RU2007126653A RU2427586C2 RU 2427586 C2 RU2427586 C2 RU 2427586C2 RU 2007126653/04 A RU2007126653/04 A RU 2007126653/04A RU 2007126653 A RU2007126653 A RU 2007126653A RU 2427586 C2 RU2427586 C2 RU 2427586C2
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- RU
- Russia
- Prior art keywords
- pyy
- ppf
- polypeptides
- ppf polypeptide
- polypeptide
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Marine Sciences & Fisheries (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54340704P | 2004-02-11 | 2004-02-11 | |
| US54340604P | 2004-02-11 | 2004-02-11 | |
| US63589704P | 2004-12-13 | 2004-12-13 | |
| US60/635,897 | 2004-12-13 | ||
| USPCT/US2005/004351 | 2005-02-11 | ||
| US11/055,098 | 2005-02-11 | ||
| PCT/US2005/004351 WO2005077094A2 (en) | 2004-02-11 | 2005-02-11 | Pancreatic polypeptide family motifs and polypeptides comprising the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2007126653A RU2007126653A (ru) | 2009-01-20 |
| RU2427586C2 true RU2427586C2 (ru) | 2011-08-27 |
Family
ID=34864523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007126653/04A RU2427586C2 (ru) | 2004-02-11 | 2005-12-12 | Мотивы семейства панкреатических полипептидов, полипептиды и способы их использования |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US8603969B2 (https=) |
| EP (3) | EP1789440A4 (https=) |
| JP (2) | JP5638177B2 (https=) |
| CN (1) | CN101111515B (https=) |
| AU (1) | AU2005211776B2 (https=) |
| CA (1) | CA2555894A1 (https=) |
| IL (1) | IL177403A0 (https=) |
| RU (1) | RU2427586C2 (https=) |
| SG (1) | SG178746A1 (https=) |
| WO (1) | WO2005077094A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2836823C2 (ru) * | 2018-02-17 | 2025-03-24 | Ридженерон Фармасьютикалз, Инк. | Gan-cnn для прогнозирования связывания mhc-пептид |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US8603969B2 (en) | 2004-02-11 | 2013-12-10 | Amylin Pharmaceuticals, Llc | Pancreatic polypeptide family motifs and polypeptides comprising the same |
| ATE471340T1 (de) | 2004-02-11 | 2010-07-15 | Amylin Pharmaceuticals Inc | Peptide der amylin familie, verfahren zu deren herstellung und verwendung |
| US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
| US7399744B2 (en) * | 2004-03-04 | 2008-07-15 | Amylin Pharmaceuticals, Inc. | Methods for affecting body composition |
| EP2060266B1 (en) * | 2004-03-17 | 2011-08-10 | 7TM Pharma A/S | Y4 selective receptor agonist PP2-36 for therapeutic interventions |
| EA011860B1 (ru) * | 2004-03-17 | 2009-06-30 | 7ТиЭм ФАРМА А/С | Селективные агонисты рецептора y2 для терапевтического воздействия |
| WO2005110467A1 (en) * | 2004-05-18 | 2005-11-24 | Aditech Pharma Ab | A composition comprising pyy for the treatment of gastrointestinal disorders |
| CA2580991A1 (en) * | 2004-10-08 | 2006-04-20 | Amylin Pharmaceuticals, Inc. | Amylin family polypeptide-6 (afp-6) analogs and methods of making and using them |
| CN101094689B (zh) | 2004-11-01 | 2013-06-12 | 安米林药品有限责任公司 | 治疗肥胖以及肥胖相关疾病和病症的方法 |
| EP2360180A3 (en) * | 2004-12-13 | 2012-02-08 | Amylin Pharmaceuticals Inc. | Pancreatic polypeptide family motifs, polypeptides and methods comprising the same |
| US7410949B2 (en) * | 2005-01-18 | 2008-08-12 | Hoffmann-La Roche Inc. | Neuropeptide-2 receptor (Y-2R) agonists and uses thereof |
| PA8660701A1 (es) * | 2005-02-04 | 2006-09-22 | Pfizer Prod Inc | Agonistas de pyy y sus usos |
| WO2007022123A2 (en) * | 2005-08-11 | 2007-02-22 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
| EP2330125A3 (en) | 2005-08-11 | 2012-12-12 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
| ATE516301T1 (de) | 2005-09-21 | 2011-07-15 | 7Tm Pharma As | Y2-selektive rezeptoragonisten für therapeutische eingriffe |
| AU2005337116A1 (en) * | 2005-09-21 | 2007-04-12 | 7Tm Pharma A/S | Y4 selective receptor agonists for therapeutic interventions |
| GB0613196D0 (en) * | 2006-07-03 | 2006-08-09 | Imp Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| AP2009005091A0 (en) | 2007-07-06 | 2009-12-31 | Theratechnologies Inc | Bifunctional fusion proteins of the alpha-melanocyte stimulating hormone (ALPHA-MSH) and atrial natriuretic protein (ANP) and uses in hypertension andacute kidney injury |
| US20100273722A1 (en) * | 2007-08-06 | 2010-10-28 | Yale University | Modified miniature proteins |
| WO2009138511A1 (en) * | 2008-05-16 | 2009-11-19 | Novo Nordisk A/S | Long-acting y2 and/or y4 receptor agonists |
| GB0817067D0 (en) * | 2008-09-18 | 2008-10-22 | 7Tm Pharma As | Intestinal treatment |
| WO2011033068A1 (en) * | 2009-09-18 | 2011-03-24 | Novo Nordisk A/S | Long-acting y2 receptor agonists |
| GB201001333D0 (en) | 2010-01-27 | 2010-03-17 | Imp Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| US8927687B2 (en) | 2010-07-09 | 2015-01-06 | Amylin Pharmaceuticals, Llc | Microcrystalline Y receptor agonists |
| SI2651398T1 (en) | 2010-12-16 | 2018-04-30 | Novo Nordisk A/S | SOLID COMPOSITIONS CONTAINING GLP-1 AGONIST AND SOL N- (8- (2-HYDROXYBENZOIL) AMINO) CAPRICULATE ACIDS |
| RU2543539C2 (ru) | 2010-12-20 | 2015-03-10 | Хилл'С Пет Ньютришн, Инк. | Кормовые композиции для домашних животных, вызывающие чувство сытости |
| GB201101459D0 (en) | 2011-01-27 | 2011-03-16 | Imp Innovations Ltd | Novel compounds and thier effects on fedding behaviour |
| US9346852B2 (en) | 2011-03-14 | 2016-05-24 | Bristol-Myers Scuibb Company | Substituted adipic acid amides and uses thereof |
| WO2013004983A1 (en) | 2011-07-04 | 2013-01-10 | Imperial Innovations Limited | Novel compounds and their effects on feeding behaviour |
| HRP20181447T1 (hr) | 2012-03-22 | 2018-11-02 | Novo Nordisk A/S | Pripravci glp-1 peptida i njihova priprava |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| AU2013366692B2 (en) | 2012-12-21 | 2017-11-23 | Sanofi | Dual GLP1/GIP or trigonal GLP1/GIP/Glucagon agonists |
| KR102272671B1 (ko) | 2013-05-02 | 2021-07-06 | 노보 노르디스크 에이/에스 | Glp-1 화합물의 경구 투여 |
| AU2014261111B2 (en) | 2013-05-02 | 2017-03-16 | Glaxosmithkline Intellectual Property Development Limited | Therapeutic peptides |
| CN105722526B (zh) | 2013-11-15 | 2020-12-08 | 诺和诺德股份有限公司 | 选择性pyy化合物及其用途 |
| EP3068795B1 (en) | 2013-11-15 | 2019-03-06 | Novo Nordisk A/S | Hpyy(1-36) having a beta-homoarginine substitution at position 35 |
| EP3080152A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Non-acylated exendin-4 peptide analogues |
| WO2015086728A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| EP3080154B1 (en) | 2013-12-13 | 2018-02-07 | Sanofi | Dual glp-1/gip receptor agonists |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| TWI694082B (zh) | 2015-06-12 | 2020-05-21 | 丹麥商諾佛 儂迪克股份有限公司 | 選擇性pyy化合物及其用途 |
| TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物 |
| JOP20190095A1 (ar) | 2016-10-27 | 2019-04-28 | Janssen Pharmaceutica Nv | مركبات ببتيد تيروسين-تيروسين الحلقية كمعدلات لمستقبلات الببتيد العصبي y |
| GB201720188D0 (en) * | 2017-12-04 | 2018-01-17 | Imperial Innovations Ltd | Analogues of PYY |
| JP6898518B2 (ja) | 2018-02-02 | 2021-07-07 | ノヴォ ノルディスク アー/エス | Glp−1アゴニスト、n−(8−(2−ヒドロキシベンゾイル)アミノ)カプリル酸の塩及び滑沢剤を含む固形組成物 |
| US11780900B2 (en) | 2018-04-25 | 2023-10-10 | Janssen Sciences Ireland Unlimited Company | Glucagon like peptide 1 (GLP-1) fusion peptide coupled cyclic peptide tyrosine tyrosine conjugates and uses thereof |
| WO2023097363A1 (en) * | 2021-11-30 | 2023-06-08 | Garvan Institute Of Medical Research | Improved binding proteins and uses thereof |
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2005
- 2005-02-11 US US11/055,098 patent/US8603969B2/en not_active Expired - Fee Related
- 2005-02-11 EP EP05722950A patent/EP1789440A4/en not_active Withdrawn
- 2005-02-11 WO PCT/US2005/004351 patent/WO2005077094A2/en not_active Ceased
- 2005-02-11 CA CA002555894A patent/CA2555894A1/en not_active Abandoned
- 2005-02-11 EP EP10013127.5A patent/EP2335715A3/en not_active Withdrawn
- 2005-02-11 JP JP2006553254A patent/JP5638177B2/ja not_active Expired - Fee Related
- 2005-02-11 AU AU2005211776A patent/AU2005211776B2/en not_active Ceased
- 2005-02-11 EP EP20100013143 patent/EP2335716A3/en not_active Withdrawn
- 2005-12-12 SG SG2012007761A patent/SG178746A1/en unknown
- 2005-12-12 US US11/301,744 patent/US7723471B2/en not_active Expired - Fee Related
- 2005-12-12 RU RU2007126653/04A patent/RU2427586C2/ru not_active IP Right Cessation
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| RU2836823C2 (ru) * | 2018-02-17 | 2025-03-24 | Ридженерон Фармасьютикалз, Инк. | Gan-cnn для прогнозирования связывания mhc-пептид |
Also Published As
| Publication number | Publication date |
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| JP5820349B2 (ja) | 2015-11-24 |
| CA2555894A1 (en) | 2005-08-25 |
| US8906849B2 (en) | 2014-12-09 |
| EP2335716A2 (en) | 2011-06-22 |
| US20060135747A1 (en) | 2006-06-22 |
| US20060094653A1 (en) | 2006-05-04 |
| IL177403A0 (en) | 2007-07-04 |
| SG178746A1 (en) | 2012-03-29 |
| US20150231204A1 (en) | 2015-08-20 |
| US20130303442A1 (en) | 2013-11-14 |
| JP5638177B2 (ja) | 2014-12-10 |
| JP2013006841A (ja) | 2013-01-10 |
| WO2005077094A3 (en) | 2007-07-12 |
| US8426361B2 (en) | 2013-04-23 |
| EP2335716A3 (en) | 2011-10-19 |
| RU2007126653A (ru) | 2009-01-20 |
| WO2005077094A2 (en) | 2005-08-25 |
| US7723471B2 (en) | 2010-05-25 |
| CN101111515B (zh) | 2013-12-11 |
| EP1789440A4 (en) | 2008-03-12 |
| EP2335715A2 (en) | 2011-06-22 |
| AU2005211776B2 (en) | 2012-02-02 |
| JP2007531711A (ja) | 2007-11-08 |
| US8603969B2 (en) | 2013-12-10 |
| EP2335715A3 (en) | 2013-12-18 |
| EP1789440A2 (en) | 2007-05-30 |
| AU2005211776A1 (en) | 2005-08-25 |
| US20100099619A1 (en) | 2010-04-22 |
| WO2005077094A9 (en) | 2006-01-26 |
| CN101111515A (zh) | 2008-01-23 |
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