IL177403A0 - Pancreatic polypeptide family polypeptides and pharmaceutical compositions containing the same - Google Patents
Pancreatic polypeptide family polypeptides and pharmaceutical compositions containing the sameInfo
- Publication number
- IL177403A0 IL177403A0 IL177403A IL17740306A IL177403A0 IL 177403 A0 IL177403 A0 IL 177403A0 IL 177403 A IL177403 A IL 177403A IL 17740306 A IL17740306 A IL 17740306A IL 177403 A0 IL177403 A0 IL 177403A0
- Authority
- IL
- Israel
- Prior art keywords
- same
- pharmaceutical compositions
- compositions containing
- pancreatic polypeptide
- family polypeptides
- Prior art date
Links
- HFDKKNHCYWNNNQ-YOGANYHLSA-N 75976-10-2 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@@H](NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)N)C(C)C)[C@@H](C)O)C1=CC=C(O)C=C1 HFDKKNHCYWNNNQ-YOGANYHLSA-N 0.000 title 1
- 102000018886 Pancreatic Polypeptide Human genes 0.000 title 1
- 101000983124 Sus scrofa Pancreatic prohormone precursor Proteins 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Marine Sciences & Fisheries (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54340704P | 2004-02-11 | 2004-02-11 | |
| US54340604P | 2004-02-11 | 2004-02-11 | |
| PCT/US2005/004351 WO2005077094A2 (en) | 2004-02-11 | 2005-02-11 | Pancreatic polypeptide family motifs and polypeptides comprising the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL177403A0 true IL177403A0 (en) | 2007-07-04 |
Family
ID=34864523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL177403A IL177403A0 (en) | 2004-02-11 | 2006-08-10 | Pancreatic polypeptide family polypeptides and pharmaceutical compositions containing the same |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US8603969B2 (https=) |
| EP (3) | EP1789440A4 (https=) |
| JP (2) | JP5638177B2 (https=) |
| CN (1) | CN101111515B (https=) |
| AU (1) | AU2005211776B2 (https=) |
| CA (1) | CA2555894A1 (https=) |
| IL (1) | IL177403A0 (https=) |
| RU (1) | RU2427586C2 (https=) |
| SG (1) | SG178746A1 (https=) |
| WO (1) | WO2005077094A2 (https=) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
| WO2005077094A2 (en) | 2004-02-11 | 2005-08-25 | Amylin Pharmaceuticals, Inc. | Pancreatic polypeptide family motifs and polypeptides comprising the same |
| RU2385878C2 (ru) | 2004-02-11 | 2010-04-10 | Амилин Фармасьютикалз, Инк. | Пептид, обладающий свойствами амилина (варианты), и его применение (варианты) |
| US7399744B2 (en) * | 2004-03-04 | 2008-07-15 | Amylin Pharmaceuticals, Inc. | Methods for affecting body composition |
| EA011860B1 (ru) * | 2004-03-17 | 2009-06-30 | 7ТиЭм ФАРМА А/С | Селективные агонисты рецептора y2 для терапевтического воздействия |
| CA2560174A1 (en) * | 2004-03-17 | 2005-09-29 | 7Tm Pharma A/S | Y4 selective receptor agonists for therapeutic interventions |
| JP2007538017A (ja) * | 2004-05-18 | 2007-12-27 | アディテック・ファルマ・アクチボラゲット | 胃腸疾患の治療のためのppy含有組成物 |
| EP2631244A1 (en) * | 2004-10-08 | 2013-08-28 | Amylin Pharmaceuticals, Inc. | Amylin family polypeptide-6 (AFP-6) analogs and methods of making and using them |
| EP2286840A3 (en) | 2004-11-01 | 2013-09-04 | Amylin Pharmaceuticals, LLC | Treatment of obesity and related diseases |
| MX2007006830A (es) * | 2004-12-13 | 2008-02-07 | Amylin Pharmaceuticals Inc | Porciones de la familia del polipeptido pancreatico, polipeptidos y metodos que comprenden las mismas. |
| US7410949B2 (en) * | 2005-01-18 | 2008-08-12 | Hoffmann-La Roche Inc. | Neuropeptide-2 receptor (Y-2R) agonists and uses thereof |
| PA8660701A1 (es) * | 2005-02-04 | 2006-09-22 | Pfizer Prod Inc | Agonistas de pyy y sus usos |
| EP2330124B1 (en) | 2005-08-11 | 2015-02-25 | Amylin Pharmaceuticals, LLC | Hybrid polypeptides with selectable properties |
| BRPI0614649A2 (pt) | 2005-08-11 | 2011-04-12 | Amylin Pharmaceuticals Inc | polipeptìdeos hìbridos com propriedades selecionáveis |
| AU2005337116A1 (en) | 2005-09-21 | 2007-04-12 | 7Tm Pharma A/S | Y4 selective receptor agonists for therapeutic interventions |
| ATE516301T1 (de) | 2005-09-21 | 2011-07-15 | 7Tm Pharma As | Y2-selektive rezeptoragonisten für therapeutische eingriffe |
| GB0613196D0 (en) * | 2006-07-03 | 2006-08-09 | Imp Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| AU2008274845A1 (en) | 2007-07-06 | 2009-01-15 | Theratechnologies Inc. | Bifunctional fusion proteins of the alpha-melanocyte stimulating hormone (alpha-MSH) and atrial natriuretic protein (ANP) and uses in hypertension and acute kidney injury |
| US20100273722A1 (en) * | 2007-08-06 | 2010-10-28 | Yale University | Modified miniature proteins |
| CN102027007A (zh) * | 2008-05-16 | 2011-04-20 | 诺沃-诺迪斯克有限公司 | 长效的y2和/或y4受体激动剂 |
| GB0817067D0 (en) * | 2008-09-18 | 2008-10-22 | 7Tm Pharma As | Intestinal treatment |
| EP2477643A1 (en) * | 2009-09-18 | 2012-07-25 | Novo Nordisk A/S | Long-acting y2 receptor agonists |
| GB201001333D0 (en) * | 2010-01-27 | 2010-03-17 | Imp Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| EP2600887A4 (en) * | 2010-07-09 | 2014-01-22 | Amylin Pharmaceuticals Llc | MICROCRYSTALLINE Y RECEPTOR AGONISTS |
| MX377589B (es) | 2010-12-16 | 2025-03-10 | Novo Nordisk As | Composiciones sólidas que comprenden agonista de glp-1 y sal del ácido n-(8-(2-hidroxibenzoil)amino)caprílico. |
| US9861116B2 (en) | 2010-12-20 | 2018-01-09 | Hill's Pet Nutrition, Inc. | Pet food compositions for inducing a satiety response |
| GB201101459D0 (en) * | 2011-01-27 | 2011-03-16 | Imp Innovations Ltd | Novel compounds and thier effects on fedding behaviour |
| WO2012125622A1 (en) | 2011-03-14 | 2012-09-20 | Bristol-Myers Squibb Company | Substituted adipic acid amides and uses thereof |
| WO2013004983A1 (en) | 2011-07-04 | 2013-01-10 | Imperial Innovations Limited | Novel compounds and their effects on feeding behaviour |
| CN104203266B (zh) | 2012-03-22 | 2017-12-26 | 诺和诺德股份有限公司 | Glp‑1肽组合物及其制备 |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| HK1211232A1 (en) | 2012-12-21 | 2016-05-20 | Sanofi | Exendin-4 derivatives as dual glp1/gip or trigonal glp1/gip/glucagon agonists |
| SG11201508469YA (en) * | 2013-05-02 | 2015-11-27 | Glaxosmithkline Ip Dev Ltd | Therapeutic peptides |
| JP6672140B2 (ja) | 2013-05-02 | 2020-03-25 | ノヴォ ノルディスク アー/エス | Glp−1化合物の経口投薬 |
| US10583172B2 (en) | 2013-11-15 | 2020-03-10 | Novo Nordisk A/S | HPYY(1-36) having a beta-homoarginine substitution at position 35 |
| MX369818B (es) | 2013-11-15 | 2019-11-22 | Novo Nordisk As | Compuestos selectivos de peptido yy (pyy) y usos de los mismos. |
| WO2015086728A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| EP3080152A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Non-acylated exendin-4 peptide analogues |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| TW201609799A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/gip受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| MA43205A (fr) | 2015-06-12 | 2018-09-19 | Novo Nordisk As | Composés pyy sélectifs et leurs utilisations |
| AR105284A1 (es) | 2015-07-10 | 2017-09-20 | Sanofi Sa | Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón |
| JOP20190095A1 (ar) | 2016-10-27 | 2019-04-28 | Janssen Pharmaceutica Nv | مركبات ببتيد تيروسين-تيروسين الحلقية كمعدلات لمستقبلات الببتيد العصبي y |
| GB201720188D0 (en) | 2017-12-04 | 2018-01-17 | Imperial Innovations Ltd | Analogues of PYY |
| PL3746111T3 (pl) | 2018-02-02 | 2024-01-15 | Novo Nordisk A/S | Stałe kompozycje zawierające agonistę glp-1 i sól kwasu n-(8-(2- hydroksybenzoilo)amino kaprylowego i substancję poślizgową |
| US11780900B2 (en) | 2018-04-25 | 2023-10-10 | Janssen Sciences Ireland Unlimited Company | Glucagon like peptide 1 (GLP-1) fusion peptide coupled cyclic peptide tyrosine tyrosine conjugates and uses thereof |
| WO2023097363A1 (en) * | 2021-11-30 | 2023-06-08 | Garvan Institute Of Medical Research | Improved binding proteins and uses thereof |
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-
2005
- 2005-02-11 WO PCT/US2005/004351 patent/WO2005077094A2/en not_active Ceased
- 2005-02-11 EP EP05722950A patent/EP1789440A4/en not_active Withdrawn
- 2005-02-11 AU AU2005211776A patent/AU2005211776B2/en not_active Ceased
- 2005-02-11 CA CA002555894A patent/CA2555894A1/en not_active Abandoned
- 2005-02-11 US US11/055,098 patent/US8603969B2/en not_active Expired - Fee Related
- 2005-02-11 EP EP20100013143 patent/EP2335716A3/en not_active Withdrawn
- 2005-02-11 JP JP2006553254A patent/JP5638177B2/ja not_active Expired - Fee Related
- 2005-02-11 EP EP10013127.5A patent/EP2335715A3/en not_active Withdrawn
- 2005-12-12 CN CN2005800471988A patent/CN101111515B/zh not_active Expired - Fee Related
- 2005-12-12 SG SG2012007761A patent/SG178746A1/en unknown
- 2005-12-12 RU RU2007126653/04A patent/RU2427586C2/ru not_active IP Right Cessation
- 2005-12-12 US US11/301,744 patent/US7723471B2/en not_active Expired - Fee Related
-
2006
- 2006-08-10 IL IL177403A patent/IL177403A0/en unknown
-
2009
- 2009-12-17 US US12/640,352 patent/US8426361B2/en not_active Expired - Fee Related
-
2012
- 2012-08-03 JP JP2012172601A patent/JP5820349B2/ja not_active Expired - Fee Related
-
2013
- 2013-04-08 US US13/858,398 patent/US8906849B2/en not_active Expired - Fee Related
-
2014
- 2014-11-12 US US14/539,540 patent/US20150231204A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005077094A2 (en) | 2005-08-25 |
| US8426361B2 (en) | 2013-04-23 |
| JP5820349B2 (ja) | 2015-11-24 |
| CA2555894A1 (en) | 2005-08-25 |
| JP2013006841A (ja) | 2013-01-10 |
| US8906849B2 (en) | 2014-12-09 |
| EP2335715A2 (en) | 2011-06-22 |
| US7723471B2 (en) | 2010-05-25 |
| WO2005077094A3 (en) | 2007-07-12 |
| CN101111515B (zh) | 2013-12-11 |
| RU2007126653A (ru) | 2009-01-20 |
| US8603969B2 (en) | 2013-12-10 |
| WO2005077094A9 (en) | 2006-01-26 |
| JP2007531711A (ja) | 2007-11-08 |
| US20060094653A1 (en) | 2006-05-04 |
| AU2005211776B2 (en) | 2012-02-02 |
| AU2005211776A1 (en) | 2005-08-25 |
| EP2335716A2 (en) | 2011-06-22 |
| US20060135747A1 (en) | 2006-06-22 |
| US20130303442A1 (en) | 2013-11-14 |
| SG178746A1 (en) | 2012-03-29 |
| US20150231204A1 (en) | 2015-08-20 |
| JP5638177B2 (ja) | 2014-12-10 |
| EP1789440A4 (en) | 2008-03-12 |
| US20100099619A1 (en) | 2010-04-22 |
| EP2335716A3 (en) | 2011-10-19 |
| EP1789440A2 (en) | 2007-05-30 |
| CN101111515A (zh) | 2008-01-23 |
| RU2427586C2 (ru) | 2011-08-27 |
| EP2335715A3 (en) | 2013-12-18 |
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