RU2329049C2 - Профилактическое и терапевтическое применение гидроксистероидов - Google Patents
Профилактическое и терапевтическое применение гидроксистероидов Download PDFInfo
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- RU2329049C2 RU2329049C2 RU2004104362/15A RU2004104362A RU2329049C2 RU 2329049 C2 RU2329049 C2 RU 2329049C2 RU 2004104362/15 A RU2004104362/15 A RU 2004104362/15A RU 2004104362 A RU2004104362 A RU 2004104362A RU 2329049 C2 RU2329049 C2 RU 2329049C2
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- 125000001981 tert-butyldimethylsilyl group Chemical group [H]C([H])([H])[Si]([H])(C([H])([H])[H])[*]C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0119810.0 | 2001-08-14 | ||
| GB0119810A GB2378898A (en) | 2001-08-14 | 2001-08-14 | Prophylactic and therapeutic use of hydroxysteroids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2004104362A RU2004104362A (ru) | 2005-05-10 |
| RU2329049C2 true RU2329049C2 (ru) | 2008-07-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004104362/15A RU2329049C2 (ru) | 2001-08-14 | 2002-08-13 | Профилактическое и терапевтическое применение гидроксистероидов |
Country Status (19)
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|---|---|
| US (1) | US8148355B2 (https=) |
| EP (1) | EP1416937B1 (https=) |
| JP (1) | JP4541698B2 (https=) |
| KR (1) | KR100895281B1 (https=) |
| CN (1) | CN1700920B (https=) |
| AT (1) | ATE429919T1 (https=) |
| AU (1) | AU2002321472B2 (https=) |
| CA (1) | CA2457050C (https=) |
| CY (1) | CY1109233T1 (https=) |
| DE (1) | DE60232154D1 (https=) |
| DK (1) | DK1416937T3 (https=) |
| ES (1) | ES2324859T3 (https=) |
| GB (1) | GB2378898A (https=) |
| IL (2) | IL160362A0 (https=) |
| NO (1) | NO334819B1 (https=) |
| NZ (1) | NZ531100A (https=) |
| PT (1) | PT1416937E (https=) |
| RU (1) | RU2329049C2 (https=) |
| WO (1) | WO2003015791A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2448712C2 (ru) * | 2006-11-30 | 2012-04-27 | Хантер-Флеминг Лимитед | Модуляция путей обмена простагландина/циклооксигеназы |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0409498D0 (en) * | 2004-04-28 | 2004-06-02 | Hunter Fleming Ltd | Transdermal steroid formulation |
| US7910755B2 (en) | 2004-09-29 | 2011-03-22 | Harbor Biosciences, Inc. | Stem cell expansion and uses |
| EP2097079B1 (en) * | 2006-11-30 | 2012-06-27 | Hunter-Fleming Limited | Modulation of prostaglandin/cyclooxygenase metabolic pathways |
| EP2653163A1 (en) * | 2012-04-19 | 2013-10-23 | Université de Liège | Estrogenic components for use in the treatment of neurological disorders |
| CN105078954A (zh) * | 2015-08-20 | 2015-11-25 | 南京华宽信息咨询中心 | 一种治疗急性肾衰药物及其应用 |
| CN105168197A (zh) * | 2015-08-22 | 2015-12-23 | 南京华宽信息咨询中心 | 一种治疗肾功能不全药物及其应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5792759A (en) * | 1995-06-23 | 1998-08-11 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl cyclopentaneperhydrophenanthrene derivatives active on the cardiovascular system, a process for their preparation and pharmaceutical compositions containing the same |
| WO1999011271A1 (en) * | 1997-08-29 | 1999-03-11 | Dalhousie University | Use of polycyclic steroid compounds for the manufacture of a medicament for the treatment of cystic kidney diseases, vascular infarction, uremia and related conditions |
| WO1999052532A1 (en) * | 1998-04-14 | 1999-10-21 | Pharmadigm, Inc. | Method for reducing central nervous system impairment |
| RU2171677C1 (ru) * | 2000-07-31 | 2001-08-10 | Саратовский научно-исследовательский институт травматологии и ортопедии | Способ лечения больных с повреждениями позвоночника и спинного мозга |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5686438A (en) * | 1993-03-09 | 1997-11-11 | University Of Utah Research Foundation | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome |
| US5977095A (en) * | 1993-03-09 | 1999-11-02 | University Of Utah Research Foundation | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and respiratory distress syndrome |
| ATE283052T1 (de) * | 1993-03-09 | 2004-12-15 | Univ Utah Res Found | Verwendung von dhea oder dessen derivate zur herstellung eines medikaments zur vorbeugung von progressiver gewebe-nekrose, reperfusionsschädigung, bakterieller translokation und vom atemnotsyndrom bei erwachsenen |
| US5846963A (en) * | 1995-06-07 | 1998-12-08 | University Of Utah Research Foundation | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome |
| US5753640A (en) * | 1995-06-07 | 1998-05-19 | University Of Utah Research Foundation | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome |
| GB0003524D0 (en) * | 2000-02-15 | 2000-04-05 | Btg Int Ltd | Cytoprotective steroids (II) |
| GB2363983A (en) * | 2000-06-29 | 2002-01-16 | Hunter Fleming Ltd | Protection against neuronal damage using 7-hydroxyepiandrosterone |
| GB2363984A (en) * | 2000-06-29 | 2002-01-16 | Hunter Fleming Ltd | Protection against neuronal damage using 3-hydroxy-7 -hydroxy steroids and 3-oxo-7 -hydroxy steroids |
-
2001
- 2001-08-14 GB GB0119810A patent/GB2378898A/en not_active Withdrawn
-
2002
- 2002-08-13 ES ES02755176T patent/ES2324859T3/es not_active Expired - Lifetime
- 2002-08-13 NZ NZ531100A patent/NZ531100A/en not_active IP Right Cessation
- 2002-08-13 US US10/486,499 patent/US8148355B2/en not_active Expired - Fee Related
- 2002-08-13 RU RU2004104362/15A patent/RU2329049C2/ru not_active IP Right Cessation
- 2002-08-13 JP JP2003520750A patent/JP4541698B2/ja not_active Expired - Fee Related
- 2002-08-13 CN CN028202627A patent/CN1700920B/zh not_active Expired - Fee Related
- 2002-08-13 CA CA2457050A patent/CA2457050C/en not_active Expired - Fee Related
- 2002-08-13 EP EP02755176A patent/EP1416937B1/en not_active Expired - Lifetime
- 2002-08-13 WO PCT/GB2002/003770 patent/WO2003015791A1/en not_active Ceased
- 2002-08-13 AU AU2002321472A patent/AU2002321472B2/en not_active Ceased
- 2002-08-13 DE DE60232154T patent/DE60232154D1/de not_active Expired - Lifetime
- 2002-08-13 PT PT02755176T patent/PT1416937E/pt unknown
- 2002-08-13 DK DK02755176T patent/DK1416937T3/da active
- 2002-08-13 IL IL16036202A patent/IL160362A0/xx active IP Right Grant
- 2002-08-13 AT AT02755176T patent/ATE429919T1/de active
- 2002-08-13 KR KR1020047002137A patent/KR100895281B1/ko not_active Expired - Fee Related
-
2004
- 2004-02-12 IL IL160362A patent/IL160362A/en not_active IP Right Cessation
- 2004-03-12 NO NO20041057A patent/NO334819B1/no not_active IP Right Cessation
-
2009
- 2009-07-20 CY CY20091100767T patent/CY1109233T1/el unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5792759A (en) * | 1995-06-23 | 1998-08-11 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl cyclopentaneperhydrophenanthrene derivatives active on the cardiovascular system, a process for their preparation and pharmaceutical compositions containing the same |
| WO1999011271A1 (en) * | 1997-08-29 | 1999-03-11 | Dalhousie University | Use of polycyclic steroid compounds for the manufacture of a medicament for the treatment of cystic kidney diseases, vascular infarction, uremia and related conditions |
| WO1999052532A1 (en) * | 1998-04-14 | 1999-10-21 | Pharmadigm, Inc. | Method for reducing central nervous system impairment |
| RU2171677C1 (ru) * | 2000-07-31 | 2001-08-10 | Саратовский научно-исследовательский институт травматологии и ортопедии | Способ лечения больных с повреждениями позвоночника и спинного мозга |
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| Title |
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| БЕЛИКОВ В.Г. Фармацевтическая химия. - М.: Высшая школа, 1993 г., т.1, с.43-47. ГЕОРГИЕВСКИЙ В.П. и КОНЕВ Ф.А. Технология и стандартизация лекарств. ООО «РИРЕГ». - Харьков, 1996 г. с.5-8. * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2448712C2 (ru) * | 2006-11-30 | 2012-04-27 | Хантер-Флеминг Лимитед | Модуляция путей обмена простагландина/циклооксигеназы |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005506321A (ja) | 2005-03-03 |
| CA2457050A1 (en) | 2003-02-27 |
| DK1416937T3 (da) | 2009-08-24 |
| KR20040041577A (ko) | 2004-05-17 |
| NZ531100A (en) | 2006-02-24 |
| US20040248868A1 (en) | 2004-12-09 |
| JP4541698B2 (ja) | 2010-09-08 |
| CN1700920A (zh) | 2005-11-23 |
| AU2002321472B2 (en) | 2007-11-08 |
| GB2378898A (en) | 2003-02-26 |
| RU2004104362A (ru) | 2005-05-10 |
| NO20041057L (no) | 2004-03-12 |
| CA2457050C (en) | 2010-10-12 |
| US8148355B2 (en) | 2012-04-03 |
| ATE429919T1 (de) | 2009-05-15 |
| ES2324859T3 (es) | 2009-08-18 |
| GB0119810D0 (en) | 2001-10-10 |
| CY1109233T1 (el) | 2014-07-02 |
| KR100895281B1 (ko) | 2009-04-29 |
| DE60232154D1 (de) | 2009-06-10 |
| EP1416937B1 (en) | 2009-04-29 |
| IL160362A (en) | 2011-10-31 |
| HK1065703A1 (en) | 2005-03-04 |
| PT1416937E (pt) | 2009-07-24 |
| WO2003015791A1 (en) | 2003-02-27 |
| IL160362A0 (en) | 2004-07-25 |
| EP1416937A1 (en) | 2004-05-12 |
| CN1700920B (zh) | 2012-05-30 |
| NO334819B1 (no) | 2014-06-10 |
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