RU2328289C2 - Контрацептивная инъекция масляного раствора, вводимая самостоятельно - Google Patents

Контрацептивная инъекция масляного раствора, вводимая самостоятельно Download PDF

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Publication number
RU2328289C2
RU2328289C2 RU2004138811/15A RU2004138811A RU2328289C2 RU 2328289 C2 RU2328289 C2 RU 2328289C2 RU 2004138811/15 A RU2004138811/15 A RU 2004138811/15A RU 2004138811 A RU2004138811 A RU 2004138811A RU 2328289 C2 RU2328289 C2 RU 2328289C2
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RU
Russia
Prior art keywords
etonogestrel
undecanoate
injection
ester
ment
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RU2004138811/15A
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English (en)
Russian (ru)
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RU2004138811A (ru
Inventor
НЕЙС Хенрик ДЕ (NL)
НЕЙС Хенрик ДЕ
Дер Ворт Хендрикус Адрианус Антониус Ван (NL)
ДЕР ВОРТ Хендрикус Адрианус Антониус ВАН
Дирк ЛЕЙСЕН (NL)
Дирк Лейсен
Original Assignee
Н.В.Органон
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Application filed by Н.В.Органон filed Critical Н.В.Органон
Publication of RU2004138811A publication Critical patent/RU2004138811A/ru
Application granted granted Critical
Publication of RU2328289C2 publication Critical patent/RU2328289C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2004138811/15A 2002-05-30 2003-05-23 Контрацептивная инъекция масляного раствора, вводимая самостоятельно RU2328289C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02077126 2002-05-30
EP02077126.7 2002-05-30

Publications (2)

Publication Number Publication Date
RU2004138811A RU2004138811A (ru) 2005-06-10
RU2328289C2 true RU2328289C2 (ru) 2008-07-10

Family

ID=29595016

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004138811/15A RU2328289C2 (ru) 2002-05-30 2003-05-23 Контрацептивная инъекция масляного раствора, вводимая самостоятельно

Country Status (23)

Country Link
US (1) US20060094698A1 (https=)
EP (1) EP1513587A1 (https=)
JP (1) JP2005533036A (https=)
KR (1) KR20050010014A (https=)
CN (1) CN1298330C (https=)
AR (1) AR040131A1 (https=)
AU (1) AU2003238084A1 (https=)
BR (1) BR0311423A (https=)
CA (1) CA2487639A1 (https=)
HR (1) HRP20041126A2 (https=)
IL (1) IL165204A0 (https=)
IS (1) IS7539A (https=)
MX (1) MXPA04011928A (https=)
NO (1) NO20044976L (https=)
NZ (1) NZ536735A (https=)
PE (1) PE20040676A1 (https=)
PL (1) PL373074A1 (https=)
RS (1) RS100904A (https=)
RU (1) RU2328289C2 (https=)
TW (1) TW200404552A (https=)
UA (1) UA80822C2 (https=)
WO (1) WO2003101539A1 (https=)
ZA (1) ZA200409646B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200727920A (en) * 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
JP6457383B2 (ja) * 2012-04-06 2019-01-23 アンタレス・ファーマ・インコーポレーテッド テストステロン組成物の針支援式ジェット注入投与
WO2014093818A2 (en) * 2012-12-14 2014-06-19 Bioject, Inc. Use of a novel subcutaneous needle-free technique to deliver testosterone in hypogonadal men
EP4349383A3 (en) * 2013-02-11 2024-06-19 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US10369340B2 (en) 2013-08-12 2019-08-06 Nanomedical Systems, Inc. Device and method for sustained release of low water solubility therapeutic agent in solubilizer
US10792292B2 (en) * 2019-03-06 2020-10-06 Propella Therapeutics, Inc. Abiraterone prodrugs
CN111057120B (zh) * 2019-12-27 2021-04-27 苏州翔实医药发展有限公司 一种依托孕烯衍生物a及其制备方法和用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0737477A1 (en) * 1993-12-27 1996-10-16 Akzo Nobel N.V. Percutaneously absorbable preparation
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
WO1997003709A1 (de) * 1995-07-17 1997-02-06 Schering Aktiengesellschaft Mittel zur transdermalen applikation enthaltend ester des 3-ketodegestrel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2970153A (en) * 1959-07-27 1961-01-31 Leo Ab Alkoxyphenyl-propionyl esters of 17alpha-hydroxyprogesterone
DE3836862A1 (de) * 1988-10-27 1990-05-03 Schering Ag Mittel zur transdermalen applikation von steroidhormonen
CN1102095A (zh) * 1993-10-30 1995-05-03 浙江医科大学 长效雄激素类制剂——十一酸睾丸注射液
DE69901250T2 (de) * 1998-06-19 2002-10-17 Akzo Nobel N.V., Arnheim/Arnhem 7.alpha.-methyl 19-nortestosteron undecanoat mit androgenischer aktivität
WO1999067270A1 (en) * 1998-06-19 1999-12-29 Akzo Nobel N.V. Cycloalkyl-carboxylic acid esters of 7.alpha.methyl-estr-4-en-3-one 17.beta.-ol (19-nor 7.alpha.-methyltestosterone)
GB0000313D0 (en) * 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation
ATE474580T1 (de) * 2000-02-15 2010-08-15 Bayer Schering Pharma Ag Zusammensetzung zur männlichen kontrazeption, norethisteron enthaltend
EP1313511B1 (en) * 2000-08-23 2005-11-30 Akzo Nobel N.V. Testosterone ester formulation for human use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0737477A1 (en) * 1993-12-27 1996-10-16 Akzo Nobel N.V. Percutaneously absorbable preparation
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
WO1997003709A1 (de) * 1995-07-17 1997-02-06 Schering Aktiengesellschaft Mittel zur transdermalen applikation enthaltend ester des 3-ketodegestrel

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KAMISCHKE A. et al. An effective hormonal male contraceptive using testosterone undecanoate with oral or injectable norethisterone preparations. The journal of clinical endocrinology and metobolism. Vol.57, no.2, 2002-02, p.530-539. *

Also Published As

Publication number Publication date
IL165204A0 (en) 2005-12-18
CA2487639A1 (en) 2003-12-11
IS7539A (is) 2004-11-18
CN1298330C (zh) 2007-02-07
JP2005533036A (ja) 2005-11-04
NZ536735A (en) 2007-01-26
MXPA04011928A (es) 2005-03-31
AU2003238084A1 (en) 2003-12-19
EP1513587A1 (en) 2005-03-16
TW200404552A (en) 2004-04-01
RS100904A (sr) 2006-10-27
ZA200409646B (en) 2006-06-28
WO2003101539A1 (en) 2003-12-11
US20060094698A1 (en) 2006-05-04
HRP20041126A2 (en) 2005-04-30
CN1655847A (zh) 2005-08-17
BR0311423A (pt) 2005-03-15
PL373074A1 (en) 2005-08-08
RU2004138811A (ru) 2005-06-10
AR040131A1 (es) 2005-03-16
UA80822C2 (en) 2007-11-12
PE20040676A1 (es) 2004-09-25
NO20044976L (no) 2004-12-23
KR20050010014A (ko) 2005-01-26

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Effective date: 20080524