JP2005533036A - 油性溶液の自己投与型避妊注射 - Google Patents

油性溶液の自己投与型避妊注射 Download PDF

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Publication number
JP2005533036A
JP2005533036A JP2004508891A JP2004508891A JP2005533036A JP 2005533036 A JP2005533036 A JP 2005533036A JP 2004508891 A JP2004508891 A JP 2004508891A JP 2004508891 A JP2004508891 A JP 2004508891A JP 2005533036 A JP2005533036 A JP 2005533036A
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Prior art keywords
ester
etonogestrel
ment
long
contraceptive
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JP2004508891A
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Japanese (ja)
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JP2005533036A5 (https=
Inventor
デ・ネイス，ヘンリツク
フアン・デル・フオート，ヘンドリクス・アドリアヌス・アントニウス
レイセン，デイルク
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アクゾ・ノベル・エヌ・ベー
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Publication of JP2005533036A publication Critical patent/JP2005533036A/ja
Publication of JP2005533036A5 publication Critical patent/JP2005533036A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2004508891A 2002-05-30 2003-05-23 油性溶液の自己投与型避妊注射 Pending JP2005533036A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02077126 2002-05-30
PCT/EP2003/050192 WO2003101539A1 (en) 2002-05-30 2003-05-23 Self-administered contraceptive injection of oily solution

Publications (2)

Publication Number Publication Date
JP2005533036A true JP2005533036A (ja) 2005-11-04
JP2005533036A5 JP2005533036A5 (https=) 2006-07-06

Family

ID=29595016

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004508891A Pending JP2005533036A (ja) 2002-05-30 2003-05-23 油性溶液の自己投与型避妊注射

Country Status (23)

Country Link
US (1) US20060094698A1 (https=)
EP (1) EP1513587A1 (https=)
JP (1) JP2005533036A (https=)
KR (1) KR20050010014A (https=)
CN (1) CN1298330C (https=)
AR (1) AR040131A1 (https=)
AU (1) AU2003238084A1 (https=)
BR (1) BR0311423A (https=)
CA (1) CA2487639A1 (https=)
HR (1) HRP20041126A2 (https=)
IL (1) IL165204A0 (https=)
IS (1) IS7539A (https=)
MX (1) MXPA04011928A (https=)
NO (1) NO20044976L (https=)
NZ (1) NZ536735A (https=)
PE (1) PE20040676A1 (https=)
PL (1) PL373074A1 (https=)
RS (1) RS100904A (https=)
RU (1) RU2328289C2 (https=)
TW (1) TW200404552A (https=)
UA (1) UA80822C2 (https=)
WO (1) WO2003101539A1 (https=)
ZA (1) ZA200409646B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022523819A (ja) * 2019-03-06 2022-04-26 プロペラ セラピューティクス インコーポレイテッド アビラテロンプロドラッグ

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200727920A (en) * 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
JP6457383B2 (ja) * 2012-04-06 2019-01-23 アンタレス・ファーマ・インコーポレーテッド テストステロン組成物の針支援式ジェット注入投与
WO2014093818A2 (en) * 2012-12-14 2014-06-19 Bioject, Inc. Use of a novel subcutaneous needle-free technique to deliver testosterone in hypogonadal men
EP4349383A3 (en) * 2013-02-11 2024-06-19 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US10369340B2 (en) 2013-08-12 2019-08-06 Nanomedical Systems, Inc. Device and method for sustained release of low water solubility therapeutic agent in solubilizer
CN111057120B (zh) * 2019-12-27 2021-04-27 苏州翔实医药发展有限公司 一种依托孕烯衍生物a及其制备方法和用途

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2970153A (en) * 1959-07-27 1961-01-31 Leo Ab Alkoxyphenyl-propionyl esters of 17alpha-hydroxyprogesterone
JPH11509222A (ja) * 1995-07-17 1999-08-17 シェリング アクチェンゲゼルシャフト １３−エチル−１７β−ヒドロキシ−１１−メチレン−１８，１９−ジノル−１７α−プレグン−４−エン−２０−イン−３−オンのエステルを含む経皮投与のための剤
WO1999067271A1 (en) * 1998-06-19 1999-12-29 Akzo Nobel N.V. Testosterone derivative
WO1999067270A1 (en) * 1998-06-19 1999-12-29 Akzo Nobel N.V. Cycloalkyl-carboxylic acid esters of 7.alpha.methyl-estr-4-en-3-one 17.beta.-ol (19-nor 7.alpha.-methyltestosterone)
WO2001060376A1 (en) * 2000-02-15 2001-08-23 Schering Aktiengesellschaft Male contraceptive formulation comprising norethisterone

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3836862A1 (de) * 1988-10-27 1990-05-03 Schering Ag Mittel zur transdermalen applikation von steroidhormonen
CN1102095A (zh) * 1993-10-30 1995-05-03 浙江医科大学 长效雄激素类制剂——十一酸睾丸注射液
CZ187796A3 (en) * 1993-12-27 1997-01-15 Akzo Nobel Nv Pharmaceutical preparation
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
GB0000313D0 (en) * 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation
EP1313511B1 (en) * 2000-08-23 2005-11-30 Akzo Nobel N.V. Testosterone ester formulation for human use

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2970153A (en) * 1959-07-27 1961-01-31 Leo Ab Alkoxyphenyl-propionyl esters of 17alpha-hydroxyprogesterone
JPH11509222A (ja) * 1995-07-17 1999-08-17 シェリング アクチェンゲゼルシャフト １３−エチル−１７β−ヒドロキシ−１１−メチレン−１８，１９−ジノル−１７α−プレグン−４−エン−２０−イン−３−オンのエステルを含む経皮投与のための剤
WO1999067271A1 (en) * 1998-06-19 1999-12-29 Akzo Nobel N.V. Testosterone derivative
WO1999067270A1 (en) * 1998-06-19 1999-12-29 Akzo Nobel N.V. Cycloalkyl-carboxylic acid esters of 7.alpha.methyl-estr-4-en-3-one 17.beta.-ol (19-nor 7.alpha.-methyltestosterone)
WO2001060376A1 (en) * 2000-02-15 2001-08-23 Schering Aktiengesellschaft Male contraceptive formulation comprising norethisterone

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6009057427, Ｋａｍｉｓｃｈｋｅ Ａ ｅｔ ａｌ, "Ａｎ ｅｆｆｅｃｔｉｖｅ ｈｏｒｍｏｎａｌ ｍａｌｅ ｃｏｎｔｒａｃｅｐｔｉｖｅ ｕｓｉｎｇ ｔｅｓｔｏｓｔｅｒｏｎｅ ｕｎｄｅｃａｎｏａｔｅ ｗｉｔｈ ｏｒａｌ ｏｒ ｉｎｊｅｃｔａｂｌｅ ｎｏｒｅ", Ｊ Ｃｌｉｎ Ｅｎｄｏｃｒｉｎｏｌ Ｍｅｔａｂ, 200202, ８７（２）, ５３０−９ *
JPN6009057428, Ｓｈｅｔｔｙ Ｇ ｅｔ ａｌ, "Ｕｓｅ ｏｆ ｎｏｒｅｔｈｉｓｔｅｒｏｎｅ ａｎｄ ｅｓｔｒａｄｉｏｌ ｉｎ ｍｉｎｉ ｄｏｓｅｓ ａｓ ａ ｃｏｎｔｒａｃｅｐｔｉｖｅ ｉｎ ｔｈｅ ｍａｌｅ． Ｅｆｆｉｃａｃｙ ｓｔｕｄｉｅｓ ｉ", Ｃｏｎｔｒａｃｅｐｔｉｏｎ, 1997, ５６（４）, ２５７−６５ *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022523819A (ja) * 2019-03-06 2022-04-26 プロペラ セラピューティクス インコーポレイテッド アビラテロンプロドラッグ
US12138273B2 (en) 2019-03-06 2024-11-12 Propella Therapeutics, Inc. Abiraterone prodrugs
JP7644713B2 (ja) 2019-03-06 2025-03-12 プロペラ セラピューティクス インコーポレイテッド アビラテロンプロドラッグ

Also Published As

Publication number Publication date
IL165204A0 (en) 2005-12-18
CA2487639A1 (en) 2003-12-11
IS7539A (is) 2004-11-18
CN1298330C (zh) 2007-02-07
RU2328289C2 (ru) 2008-07-10
NZ536735A (en) 2007-01-26
MXPA04011928A (es) 2005-03-31
AU2003238084A1 (en) 2003-12-19
EP1513587A1 (en) 2005-03-16
TW200404552A (en) 2004-04-01
RS100904A (sr) 2006-10-27
ZA200409646B (en) 2006-06-28
WO2003101539A1 (en) 2003-12-11
US20060094698A1 (en) 2006-05-04
HRP20041126A2 (en) 2005-04-30
CN1655847A (zh) 2005-08-17
BR0311423A (pt) 2005-03-15
PL373074A1 (en) 2005-08-08
RU2004138811A (ru) 2005-06-10
AR040131A1 (es) 2005-03-16
UA80822C2 (en) 2007-11-12
PE20040676A1 (es) 2004-09-25
NO20044976L (no) 2004-12-23
KR20050010014A (ko) 2005-01-26

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