CA2487639A1 - Self-administered contraceptive injection of oily solution - Google Patents

Self-administered contraceptive injection of oily solution Download PDF

Info

Publication number
CA2487639A1
CA2487639A1 CA002487639A CA2487639A CA2487639A1 CA 2487639 A1 CA2487639 A1 CA 2487639A1 CA 002487639 A CA002487639 A CA 002487639A CA 2487639 A CA2487639 A CA 2487639A CA 2487639 A1 CA2487639 A1 CA 2487639A1
Authority
CA
Canada
Prior art keywords
etonogestrel
ester
undecanoate
ment
long
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002487639A
Other languages
English (en)
French (fr)
Inventor
Henrik De Nijs
Hendrikus Adrianus Antonius Van Der Voort
Dirk Leysen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2487639A1 publication Critical patent/CA2487639A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002487639A 2002-05-30 2003-05-23 Self-administered contraceptive injection of oily solution Abandoned CA2487639A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02077126 2002-05-30
EP02077126.7 2002-05-30
PCT/EP2003/050192 WO2003101539A1 (en) 2002-05-30 2003-05-23 Self-administered contraceptive injection of oily solution

Publications (1)

Publication Number Publication Date
CA2487639A1 true CA2487639A1 (en) 2003-12-11

Family

ID=29595016

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002487639A Abandoned CA2487639A1 (en) 2002-05-30 2003-05-23 Self-administered contraceptive injection of oily solution

Country Status (23)

Country Link
US (1) US20060094698A1 (https=)
EP (1) EP1513587A1 (https=)
JP (1) JP2005533036A (https=)
KR (1) KR20050010014A (https=)
CN (1) CN1298330C (https=)
AR (1) AR040131A1 (https=)
AU (1) AU2003238084A1 (https=)
BR (1) BR0311423A (https=)
CA (1) CA2487639A1 (https=)
HR (1) HRP20041126A2 (https=)
IL (1) IL165204A0 (https=)
IS (1) IS7539A (https=)
MX (1) MXPA04011928A (https=)
NO (1) NO20044976L (https=)
NZ (1) NZ536735A (https=)
PE (1) PE20040676A1 (https=)
PL (1) PL373074A1 (https=)
RS (1) RS100904A (https=)
RU (1) RU2328289C2 (https=)
TW (1) TW200404552A (https=)
UA (1) UA80822C2 (https=)
WO (1) WO2003101539A1 (https=)
ZA (1) ZA200409646B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200727920A (en) * 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
JP6457383B2 (ja) * 2012-04-06 2019-01-23 アンタレス・ファーマ・インコーポレーテッド テストステロン組成物の針支援式ジェット注入投与
WO2014093818A2 (en) * 2012-12-14 2014-06-19 Bioject, Inc. Use of a novel subcutaneous needle-free technique to deliver testosterone in hypogonadal men
EP4349383A3 (en) * 2013-02-11 2024-06-19 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US10369340B2 (en) 2013-08-12 2019-08-06 Nanomedical Systems, Inc. Device and method for sustained release of low water solubility therapeutic agent in solubilizer
US10792292B2 (en) * 2019-03-06 2020-10-06 Propella Therapeutics, Inc. Abiraterone prodrugs
CN111057120B (zh) * 2019-12-27 2021-04-27 苏州翔实医药发展有限公司 一种依托孕烯衍生物a及其制备方法和用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2970153A (en) * 1959-07-27 1961-01-31 Leo Ab Alkoxyphenyl-propionyl esters of 17alpha-hydroxyprogesterone
DE3836862A1 (de) * 1988-10-27 1990-05-03 Schering Ag Mittel zur transdermalen applikation von steroidhormonen
CN1102095A (zh) * 1993-10-30 1995-05-03 浙江医科大学 长效雄激素类制剂——十一酸睾丸注射液
CZ187796A3 (en) * 1993-12-27 1997-01-15 Akzo Nobel Nv Pharmaceutical preparation
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
AU6614096A (en) * 1995-07-17 1997-02-18 Schering Aktiengesellschaft Agent, for transdermal application, containing esters of 3-ketodesogestrel
DE69901250T2 (de) * 1998-06-19 2002-10-17 Akzo Nobel N.V., Arnheim/Arnhem 7.alpha.-methyl 19-nortestosteron undecanoat mit androgenischer aktivität
WO1999067270A1 (en) * 1998-06-19 1999-12-29 Akzo Nobel N.V. Cycloalkyl-carboxylic acid esters of 7.alpha.methyl-estr-4-en-3-one 17.beta.-ol (19-nor 7.alpha.-methyltestosterone)
GB0000313D0 (en) * 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation
ATE474580T1 (de) * 2000-02-15 2010-08-15 Bayer Schering Pharma Ag Zusammensetzung zur männlichen kontrazeption, norethisteron enthaltend
EP1313511B1 (en) * 2000-08-23 2005-11-30 Akzo Nobel N.V. Testosterone ester formulation for human use

Also Published As

Publication number Publication date
IL165204A0 (en) 2005-12-18
IS7539A (is) 2004-11-18
CN1298330C (zh) 2007-02-07
RU2328289C2 (ru) 2008-07-10
JP2005533036A (ja) 2005-11-04
NZ536735A (en) 2007-01-26
MXPA04011928A (es) 2005-03-31
AU2003238084A1 (en) 2003-12-19
EP1513587A1 (en) 2005-03-16
TW200404552A (en) 2004-04-01
RS100904A (sr) 2006-10-27
ZA200409646B (en) 2006-06-28
WO2003101539A1 (en) 2003-12-11
US20060094698A1 (en) 2006-05-04
HRP20041126A2 (en) 2005-04-30
CN1655847A (zh) 2005-08-17
BR0311423A (pt) 2005-03-15
PL373074A1 (en) 2005-08-08
RU2004138811A (ru) 2005-06-10
AR040131A1 (es) 2005-03-16
UA80822C2 (en) 2007-11-12
PE20040676A1 (es) 2004-09-25
NO20044976L (no) 2004-12-23
KR20050010014A (ko) 2005-01-26

Similar Documents

Publication Publication Date Title
DE60310714T2 (de) Etonogestrelester
MX2012006755A (es) Gel transdermico de progestina/estradiol.
JP2010511730A (ja) テストステロンおよびプロゲスターゲンを用いたドライアイのための処置
WO2000074684A1 (en) Pharmaceutical formulations for treating postmenopausal and perimenopausal women, and their use
CA2487639A1 (en) Self-administered contraceptive injection of oily solution
Thorneycroft Update on androgenicity
EP1513588B1 (en) Use of new etonogestrel esters
WO2004096191A1 (de) Pharmazeutische zusammensetzung in form eines hydrogels zur transdermalen verabreichung von wirkstoffen
US4794119A (en) Aqueous crystalline suspension of steroid glycoesters
HK1072568B (en) Use of new etonogestrel esters
SWYER PROGESTOGENS AND THEIR CLINICAL USES: PARTI

Legal Events

Date Code Title Description
FZDE Discontinued