RU2191778C2 - Производные пурина, фармацевтическая композиция и способ лечения - Google Patents

Производные пурина, фармацевтическая композиция и способ лечения Download PDF

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Publication number
RU2191778C2
RU2191778C2 RU99105119/04A RU99105119A RU2191778C2 RU 2191778 C2 RU2191778 C2 RU 2191778C2 RU 99105119/04 A RU99105119/04 A RU 99105119/04A RU 99105119 A RU99105119 A RU 99105119A RU 2191778 C2 RU2191778 C2 RU 2191778C2
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RU
Russia
Prior art keywords
alkyl
cyanophenoxy
amino
pyrimidine
methyl
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RU99105119/04A
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English (en)
Russian (ru)
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RU99105119A (ru
Inventor
Майкл М. МОРРИССЕЙ (US)
Майкл М. Морриссей
Бред БАКМЕН (US)
Бред БАКМЕН
Раджу МОХАН (US)
Раджу Мохан
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Шеринг Акциенгезелльшафт
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Publication of RU99105119A publication Critical patent/RU99105119A/ru
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RU99105119/04A 1996-08-16 1997-08-14 Производные пурина, фармацевтическая композиция и способ лечения RU2191778C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/689,979 1996-08-16
US08/689,979 US5753635A (en) 1996-08-16 1996-08-16 Purine derivatives and their use as anti-coagulants

Publications (2)

Publication Number Publication Date
RU99105119A RU99105119A (ru) 2001-01-20
RU2191778C2 true RU2191778C2 (ru) 2002-10-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU99105119/04A RU2191778C2 (ru) 1996-08-16 1997-08-14 Производные пурина, фармацевтическая композиция и способ лечения

Country Status (23)

Country Link
US (1) US5753635A (da)
EP (1) EP0920430B1 (da)
JP (1) JP2000516242A (da)
KR (1) KR20000068177A (da)
CN (1) CN1096461C (da)
AT (1) ATE250606T1 (da)
AU (1) AU722631B2 (da)
CA (1) CA2262876A1 (da)
CZ (1) CZ50299A3 (da)
DE (1) DE69725151T2 (da)
DK (1) DK0920430T3 (da)
ES (1) ES2206746T3 (da)
HK (1) HK1020057A1 (da)
HU (1) HUP9902308A3 (da)
IL (1) IL128160A (da)
NO (1) NO314584B1 (da)
NZ (1) NZ333895A (da)
PL (1) PL331608A1 (da)
PT (1) PT920430E (da)
RU (1) RU2191778C2 (da)
SK (1) SK19399A3 (da)
UA (1) UA57746C2 (da)
WO (1) WO1998007725A1 (da)

Cited By (1)

* Cited by examiner, † Cited by third party
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RU2496780C2 (ru) * 2006-10-27 2013-10-27 СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи Твердые формы

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2496780C2 (ru) * 2006-10-27 2013-10-27 СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи Твердые формы

Also Published As

Publication number Publication date
DE69725151T2 (de) 2004-06-09
EP0920430B1 (en) 2003-09-24
US5753635A (en) 1998-05-19
NZ333895A (en) 2000-07-28
CN1096461C (zh) 2002-12-18
NO990673L (no) 1999-04-15
WO1998007725A1 (en) 1998-02-26
ATE250606T1 (de) 2003-10-15
CN1228092A (zh) 1999-09-08
AU4118697A (en) 1998-03-06
DK0920430T3 (da) 2003-11-17
KR20000068177A (ko) 2000-11-25
HUP9902308A2 (en) 2000-07-28
SK19399A3 (en) 1999-08-06
DE69725151D1 (de) 2003-10-30
NO990673D0 (no) 1999-02-12
AU722631B2 (en) 2000-08-10
IL128160A0 (en) 1999-11-30
IL128160A (en) 2003-04-10
CZ50299A3 (cs) 1999-06-16
CA2262876A1 (en) 1998-02-26
PT920430E (pt) 2003-12-31
UA57746C2 (uk) 2003-07-15
HK1020057A1 (en) 2000-03-10
EP0920430A1 (en) 1999-06-09
PL331608A1 (en) 1999-08-02
ES2206746T3 (es) 2004-05-16
NO314584B1 (no) 2003-04-14
JP2000516242A (ja) 2000-12-05
HUP9902308A3 (en) 2000-08-28

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RH4A Copy of patent granted that was duplicated for the russian federation

Effective date: 20060520

NF4A Reinstatement of patent
MM4A The patent is invalid due to non-payment of fees

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