RU2184116C1 - Способ получения пиперидиниламинометил-трифторметиловых циклических эфиров - Google Patents

Способ получения пиперидиниламинометил-трифторметиловых циклических эфиров Download PDF

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Publication number
RU2184116C1
RU2184116C1 RU2000126151/04A RU2000126151A RU2184116C1 RU 2184116 C1 RU2184116 C1 RU 2184116C1 RU 2000126151/04 A RU2000126151/04 A RU 2000126151/04A RU 2000126151 A RU2000126151 A RU 2000126151A RU 2184116 C1 RU2184116 C1 RU 2184116C1
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RU
Russia
Prior art keywords
alkyl
formula
acid
compound
compounds
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RU2000126151/04A
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English (en)
Russian (ru)
Inventor
Стефан Карон
Энрике ВАСКЕС
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Пфайзер Продактс Инк.
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Publication of RU2184116C1 publication Critical patent/RU2184116C1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76—Benzo[c]pyrans

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
RU2000126151/04A 1999-10-18 2000-10-17 Способ получения пиперидиниламинометил-трифторметиловых циклических эфиров RU2184116C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16022699P 1999-10-18 1999-10-18
US60/160,226 1999-10-18

Publications (1)

Publication Number Publication Date
RU2184116C1 true RU2184116C1 (ru) 2002-06-27

Family

ID=22576040

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2000126151/04A RU2184116C1 (ru) 1999-10-18 2000-10-17 Способ получения пиперидиниламинометил-трифторметиловых циклических эфиров

Country Status (24)

Country Link
US (2) US6486325B1 (xx)
EP (1) EP1095939B1 (xx)
JP (1) JP3564685B2 (xx)
KR (1) KR100459952B1 (xx)
CN (1) CN1293193A (xx)
AR (1) AR026053A1 (xx)
AT (1) ATE257477T1 (xx)
AU (1) AU784275B2 (xx)
BR (1) BR0004901A (xx)
CA (1) CA2323315C (xx)
CZ (1) CZ299029B6 (xx)
DE (1) DE60007599T2 (xx)
DK (1) DK1095939T3 (xx)
ES (1) ES2211455T3 (xx)
HU (1) HUP0004061A2 (xx)
ID (1) ID27627A (xx)
IL (1) IL139012A (xx)
IN (1) IN190078B (xx)
PL (1) PL343290A1 (xx)
PT (1) PT1095939E (xx)
RU (1) RU2184116C1 (xx)
TR (1) TR200003002A2 (xx)
YU (1) YU60600A (xx)
ZA (1) ZA200005695B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
WO2003053929A1 (fr) * 2001-12-21 2003-07-03 Toray Fine Chemicals Co., Ltd. Procede de production de derives de cis-piperidine optiquement actifs

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0581777A1 (en) * 1991-03-26 1994-02-09 Pfizer Inc. Stereoselective preparation of substituted piperidines
US5294744A (en) * 1993-04-20 1994-03-15 Pfizer Inc. Formylation process for aromatic aldehydes
ES2155601T3 (es) * 1995-07-07 2001-05-16 Pfizer Compuestos de benzolactama sustituidos como antagonistas de la sustancia p.
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
CA2374643C (en) * 1999-05-21 2006-02-14 Pfizer Products Inc. 1-trifluoromethyl-4-hydroxy-7-piperidinylaminomethylchroman derivatives as substance p antagonists

Also Published As

Publication number Publication date
PL343290A1 (en) 2001-04-23
CZ20003840A3 (cs) 2002-02-13
JP3564685B2 (ja) 2004-09-15
ES2211455T3 (es) 2004-07-16
ZA200005695B (en) 2002-04-16
PT1095939E (pt) 2004-04-30
DK1095939T3 (da) 2004-04-13
BR0004901A (pt) 2001-05-29
HU0004061D0 (en) 2000-12-28
IL139012A0 (en) 2001-11-25
KR100459952B1 (ko) 2004-12-04
IL139012A (en) 2007-06-17
US20030236268A1 (en) 2003-12-25
HUP0004061A2 (hu) 2002-05-29
DE60007599D1 (de) 2004-02-12
EP1095939B1 (en) 2004-01-07
CN1293193A (zh) 2001-05-02
AR026053A1 (es) 2002-12-26
ID27627A (id) 2001-04-19
IN190078B (xx) 2003-06-07
EP1095939A2 (en) 2001-05-02
CA2323315C (en) 2008-07-29
US6486325B1 (en) 2002-11-26
CA2323315A1 (en) 2001-04-18
EP1095939A3 (en) 2001-05-23
CZ299029B6 (cs) 2008-04-09
AU6547400A (en) 2001-04-26
ATE257477T1 (de) 2004-01-15
KR20010051069A (ko) 2001-06-25
AU784275B2 (en) 2006-03-02
DE60007599T2 (de) 2004-11-11
YU60600A (sh) 2002-12-10
JP2001151773A (ja) 2001-06-05
TR200003002A2 (tr) 2001-05-21

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20081018