RU2166320C2 - Антигипертриглицеридемическая композиция (варианты), способ ее получения, способ лечения или профилактики гипертриглицеридемии - Google Patents

Антигипертриглицеридемическая композиция (варианты), способ ее получения, способ лечения или профилактики гипертриглицеридемии Download PDF

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RU2166320C2
RU2166320C2 RU95117068/14A RU95117068A RU2166320C2 RU 2166320 C2 RU2166320 C2 RU 2166320C2 RU 95117068/14 A RU95117068/14 A RU 95117068/14A RU 95117068 A RU95117068 A RU 95117068A RU 2166320 C2 RU2166320 C2 RU 2166320C2
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Russia
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substituted
group
oxo
tetrahydro
hypertriglyceridemia
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RU95117068/14A
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English (en)
Russian (ru)
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RU95117068A (ru
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Сугияма Ясуо
Юкимаса Хидефуми
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Такеда Кемикал Индастриз, Лтд.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
RU95117068/14A 1994-10-07 1995-10-06 Антигипертриглицеридемическая композиция (варианты), способ ее получения, способ лечения или профилактики гипертриглицеридемии RU2166320C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24413694 1994-10-07
JP06-244136 1994-10-07

Publications (2)

Publication Number Publication Date
RU95117068A RU95117068A (ru) 1998-01-10
RU2166320C2 true RU2166320C2 (ru) 2001-05-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU95117068/14A RU2166320C2 (ru) 1994-10-07 1995-10-06 Антигипертриглицеридемическая композиция (варианты), способ ее получения, способ лечения или профилактики гипертриглицеридемии

Country Status (11)

Country Link
EP (1) EP0705607A2 (cg-RX-API-DMAC10.html)
KR (1) KR960013370A (cg-RX-API-DMAC10.html)
CN (1) CN1128657A (cg-RX-API-DMAC10.html)
AU (1) AU703422B2 (cg-RX-API-DMAC10.html)
CA (1) CA2160092A1 (cg-RX-API-DMAC10.html)
FI (1) FI954773A7 (cg-RX-API-DMAC10.html)
HU (1) HUT73422A (cg-RX-API-DMAC10.html)
NO (1) NO308580B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ280165A (cg-RX-API-DMAC10.html)
RU (1) RU2166320C2 (cg-RX-API-DMAC10.html)
TW (1) TW401301B (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2271808C2 (ru) * 2001-06-06 2006-03-20 Ф. Хоффманн-Ля Рош Аг Фармацевтическая композиция, включающая ингибитор липазы и жирнокислотный сложный эфир сахарозы

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CN1072649C (zh) * 1995-09-13 2001-10-10 武田药品工业株式会社 苯并氧杂吖庚因化合物,其生产方法和用途
PT862562E (pt) * 1995-09-13 2001-11-30 Takeda Chemical Industries Ltd Compostos de benzoxazepina sua producao e utilizacao como agentes para reducao dos niveis de lipidos
EP0843559A2 (en) * 1996-06-11 1998-05-27 Zonagen, Inc. Chitosan drug delivery system
CN1252795A (zh) 1997-04-21 2000-05-10 武田药品工业株式会社 4,1－苯并氧氮杂、它们的类似物和它们作为抑生长素兴奋剂的用途
JP4204657B2 (ja) * 1997-12-05 2009-01-07 有限会社ケムフィズ 糖尿病の予防・治療剤
KR100584650B1 (ko) 1998-03-31 2006-05-30 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 치환된 인돌알칸산
US6207664B1 (en) 1998-11-25 2001-03-27 Pfizer Inc. Squalene synthetase inhibitor agents
TNSN99224A1 (fr) * 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
AU5588400A (en) 1999-05-26 2000-12-18 Du Pont Pharmaceuticals Company 1,4-benzodiazepin-2-ones useful as hiv reverse transcriptase inhibitors
EP1210338A2 (en) * 1999-08-05 2002-06-05 IGT Pharma Inc. 1,4-diazepine derivatives for the treatment of diseases related to the central nervous system
KR20030048465A (ko) * 2000-11-09 2003-06-19 다케다 야쿠힌 고교 가부시키가이샤 고밀도 지질단백질-콜레스테롤 상승제
EP1365745A2 (en) 2001-02-15 2003-12-03 King Pharmaceuticals, Inc. Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
EP1407782A4 (en) * 2001-06-28 2004-10-20 Takeda Chemical Industries Ltd AGENTS FOR PREVENTION / TREATMENT OF FUNCTIONAL ORGANIC DISEASES AND ORGANIC DYSFUNCTION
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
CA2514547A1 (en) 2003-01-28 2004-08-12 Takeda Pharmaceutical Company Limited Receptor agonists
CA2546601A1 (en) 2003-11-19 2005-06-09 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
JP2008509074A (ja) * 2004-08-09 2008-03-27 武田薬品工業株式会社 Ｃｒｐ低下剤
US7790745B2 (en) 2005-10-21 2010-09-07 Bristol-Myers Squibb Company Tetrahydroisoquinoline LXR Modulators
RU2008119687A (ru) 2005-10-21 2009-11-27 Новартис АГ (CH) Комбинации органических соединений
BRPI0811204A8 (pt) 2007-05-10 2015-09-22 Bristol Myers Squibb Co Tetra-hidroibenzo-1,4-diazepinas substituídas por arila e heteroarila e uso das mesmas para bloquear a recaptação de norepinefrina, dopamina e serotonina
US20120046364A1 (en) 2009-02-10 2012-02-23 Metabasis Therapeutics, Inc. Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
KR20240131463A (ko) 2020-05-05 2024-08-30 뉴베일런트, 아이엔씨. 헤테로방향족 거대환식 에터 화학치료제
JP7519463B2 (ja) 2020-05-05 2024-07-19 ヌバレント， インク． ヘテロ芳香族大環状エーテル化学療法剤
CN118234725A (zh) 2021-10-01 2024-06-21 纽威伦特公司 杂芳族大环醚化合物的固体形式、药物组合物及制备

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US5153190A (en) * 1990-03-08 1992-10-06 Adir Et Compagnie Pyrrolo [1,2A] thieno [3,2-F] [1,4] diazepines
US5180717A (en) * 1988-08-16 1993-01-19 The Upjohn Company Bivalent ligands effective for blocking ACAT enzyme for lowering plasma triglycerides and for elevating HDL cholesterol
EP0579222A2 (en) * 1992-07-17 1994-01-19 Senju Pharmaceutical Co., Ltd. Lipid metabolism improving composition

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AU678503B2 (en) * 1993-09-24 1997-05-29 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds and their use as squalene synthetase inhibitors
WO1995021834A1 (en) * 1994-02-09 1995-08-17 Takeda Chemical Industries, Ltd. Optically active 4,1-benzoxazepine derivatives useful as squalene synthase inhibitors

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US5180717A (en) * 1988-08-16 1993-01-19 The Upjohn Company Bivalent ligands effective for blocking ACAT enzyme for lowering plasma triglycerides and for elevating HDL cholesterol
US5153190A (en) * 1990-03-08 1992-10-06 Adir Et Compagnie Pyrrolo [1,2A] thieno [3,2-F] [1,4] diazepines
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Cited By (1)

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Publication number Priority date Publication date Assignee Title
RU2271808C2 (ru) * 2001-06-06 2006-03-20 Ф. Хоффманн-Ля Рош Аг Фармацевтическая композиция, включающая ингибитор липазы и жирнокислотный сложный эфир сахарозы

Also Published As

Publication number Publication date
NO953961D0 (no) 1995-10-05
TW401301B (en) 2000-08-11
KR960013370A (ko) 1996-05-22
EP0705607A3 (cg-RX-API-DMAC10.html) 1996-05-08
EP0705607A2 (en) 1996-04-10
CA2160092A1 (en) 1996-04-08
NO308580B1 (no) 2000-10-02
NO953961L (no) 1996-04-09
FI954773A0 (fi) 1995-10-06
AU3308195A (en) 1996-04-18
FI954773A7 (fi) 1996-04-08
AU703422B2 (en) 1999-03-25
CN1128657A (zh) 1996-08-14
HU9502918D0 (en) 1995-11-28
NZ280165A (en) 1997-07-27
HUT73422A (en) 1996-07-29

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