RU2125557C1 - Замещенные 2-гидрокси-3-[1-(1h-имидазол-4-ил)-алкил] - бензолкарбоксимидамиды, их оптические изомеры, их рацемические смеси или их нетоксичные, офтальмологически приемлемые соли присоединения кислот. - Google Patents

Замещенные 2-гидрокси-3-[1-(1h-имидазол-4-ил)-алкил] - бензолкарбоксимидамиды, их оптические изомеры, их рацемические смеси или их нетоксичные, офтальмологически приемлемые соли присоединения кислот. Download PDF

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Publication number
RU2125557C1
RU2125557C1 RU94018525A RU94018525A RU2125557C1 RU 2125557 C1 RU2125557 C1 RU 2125557C1 RU 94018525 A RU94018525 A RU 94018525A RU 94018525 A RU94018525 A RU 94018525A RU 2125557 C1 RU2125557 C1 RU 2125557C1
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RU
Russia
Prior art keywords
imidazol
hydroxy
formula
alkyl
methyl
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RU94018525A
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English (en)
Russian (ru)
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RU94018525A (ru
Inventor
Мишель ФИЛИПП
Коссеман Эрик
Гобер Жан
Вюлферт Эрнст
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Юцб
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Publication of RU94018525A publication Critical patent/RU94018525A/ru
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Publication of RU2125557C1 publication Critical patent/RU2125557C1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RU94018525A 1993-05-27 1994-05-25 Замещенные 2-гидрокси-3-[1-(1h-имидазол-4-ил)-алкил] - бензолкарбоксимидамиды, их оптические изомеры, их рацемические смеси или их нетоксичные, офтальмологически приемлемые соли присоединения кислот. RU2125557C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9310965.0 1993-05-27
GB939310965A GB9310965D0 (en) 1993-05-27 1993-05-27 2-hydroxy-3-(1h-imidazol-4-yl)alkyl)benzenecarboximidamides

Publications (2)

Publication Number Publication Date
RU94018525A RU94018525A (ru) 1996-03-20
RU2125557C1 true RU2125557C1 (ru) 1999-01-27

Family

ID=10736226

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94018525A RU2125557C1 (ru) 1993-05-27 1994-05-25 Замещенные 2-гидрокси-3-[1-(1h-имидазол-4-ил)-алкил] - бензолкарбоксимидамиды, их оптические изомеры, их рацемические смеси или их нетоксичные, офтальмологически приемлемые соли присоединения кислот.

Country Status (21)

Country Link
US (1) US5385927A (https=)
EP (1) EP0626372B1 (https=)
JP (1) JPH0770082A (https=)
AT (1) ATE198196T1 (https=)
AU (1) AU673422B2 (https=)
CA (1) CA2124289A1 (https=)
CZ (1) CZ287136B6 (https=)
DE (1) DE69426433D1 (https=)
FI (1) FI942390L (https=)
GB (1) GB9310965D0 (https=)
HU (1) HUT67813A (https=)
IL (1) IL109750A (https=)
MY (1) MY111216A (https=)
NO (1) NO303824B1 (https=)
NZ (1) NZ260588A (https=)
PL (1) PL175970B1 (https=)
RU (1) RU2125557C1 (https=)
SG (1) SG42791A1 (https=)
SK (1) SK60394A3 (https=)
TW (1) TW263500B (https=)
ZA (1) ZA943651B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2311928C2 (ru) * 2000-07-14 2007-12-10 Аллерган Инк. Композиции, содержащие альфа-2-адренергические агонисты

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9521680D0 (en) * 1995-10-23 1996-01-03 Orion Yhtymo Oy New use of imidazole derivatives
US6200967B1 (en) 1996-06-25 2001-03-13 Eli Lilly And Company Anticoagulant agents
CA2258915A1 (en) * 1996-06-25 1997-12-31 Michael Robert Wiley Anticoagulant agents
US7902247B2 (en) * 2008-01-09 2011-03-08 Allergan, Inc. Substituted-aryl-2-phenylethyl-1H-imidazole compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors
EP2196461A1 (de) 2008-12-15 2010-06-16 Bayer CropScience AG 4-Amino-1,2,3-benzoxathiazin-Derivate als Pestizide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8626287D0 (en) * 1986-11-04 1986-12-03 Ucb Sa Substituted 1h-imidazoles
GB8810067D0 (en) * 1988-04-28 1988-06-02 Ucb Sa Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides
FI98815C (fi) * 1990-11-30 1997-08-25 Santen Oy Menetelmä uusien, farmakologisesti käyttökelpoisten bispilokarpiinihapon esterijohdannaisten valmistamiseksi

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2311928C2 (ru) * 2000-07-14 2007-12-10 Аллерган Инк. Композиции, содержащие альфа-2-адренергические агонисты

Also Published As

Publication number Publication date
HUT67813A (en) 1995-05-29
TW263500B (https=) 1995-11-21
PL175970B1 (pl) 1999-03-31
ZA943651B (en) 1995-01-26
US5385927A (en) 1995-01-31
EP0626372B1 (fr) 2000-12-20
MY111216A (en) 1999-09-30
NO941932D0 (no) 1994-05-25
CZ287136B6 (en) 2000-09-13
JPH0770082A (ja) 1995-03-14
IL109750A0 (en) 1994-08-26
NO941932L (no) 1994-11-28
DE69426433D1 (de) 2001-01-25
CA2124289A1 (en) 1994-11-28
NO303824B1 (no) 1998-09-07
AU6330394A (en) 1994-12-01
FI942390A7 (fi) 1994-11-28
EP0626372A1 (fr) 1994-11-30
IL109750A (en) 1998-06-15
FI942390L (fi) 1994-11-28
NZ260588A (en) 1995-09-26
SG42791A1 (en) 1997-10-17
AU673422B2 (en) 1996-11-07
CZ124794A3 (en) 1994-12-15
FI942390A0 (fi) 1994-05-24
SK60394A3 (en) 1995-07-11
ATE198196T1 (de) 2001-01-15
HU9401574D0 (en) 1994-08-29
GB9310965D0 (en) 1993-07-14

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