RU2099333C1 - Производное 3-дезоксиманнозамина, способ его получения и фармацевтическая композиция, обладающая ингибирующей активностью к развитию сосудов и метастазов - Google Patents

Производное 3-дезоксиманнозамина, способ его получения и фармацевтическая композиция, обладающая ингибирующей активностью к развитию сосудов и метастазов Download PDF

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RU2099333C1
RU2099333C1 SU925052492A SU5052492A RU2099333C1 RU 2099333 C1 RU2099333 C1 RU 2099333C1 SU 925052492 A SU925052492 A SU 925052492A SU 5052492 A SU5052492 A SU 5052492A RU 2099333 C1 RU2099333 C1 RU 2099333C1
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Russia
Prior art keywords
mannopyranose
dideoxy
formula
compound
acetamido
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SU925052492A
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English (en)
Russian (ru)
Inventor
Монгелли Никола
Барджиотти Альберто
Онето Нуччиа
Джерони Кристина
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Фармиталиа Карло Эрба С.Р.Л.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SU925052492A 1991-08-06 1992-08-05 Производное 3-дезоксиманнозамина, способ его получения и фармацевтическая композиция, обладающая ингибирующей активностью к развитию сосудов и метастазов RU2099333C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919116896A GB9116896D0 (en) 1991-08-06 1991-08-06 3-deoxymannosamine derivatives and process for their preparation
GB9116896.3 1991-08-06

Publications (1)

Publication Number Publication Date
RU2099333C1 true RU2099333C1 (ru) 1997-12-20

Family

ID=10699545

Family Applications (1)

Application Number Title Priority Date Filing Date
SU925052492A RU2099333C1 (ru) 1991-08-06 1992-08-05 Производное 3-дезоксиманнозамина, способ его получения и фармацевтическая композиция, обладающая ингибирующей активностью к развитию сосудов и метастазов

Country Status (16)

Country Link
US (1) US5332756A (OSRAM)
EP (1) EP0527042A2 (OSRAM)
JP (1) JPH05208988A (OSRAM)
KR (1) KR930004325A (OSRAM)
AU (1) AU646173B2 (OSRAM)
CA (1) CA2075336A1 (OSRAM)
FI (1) FI923498A7 (OSRAM)
GB (1) GB9116896D0 (OSRAM)
HU (1) HU213208B (OSRAM)
IL (1) IL102500A (OSRAM)
MX (1) MX9204395A (OSRAM)
MY (1) MY108749A (OSRAM)
NZ (1) NZ243627A (OSRAM)
RU (1) RU2099333C1 (OSRAM)
TW (1) TW248564B (OSRAM)
ZA (1) ZA925871B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2266734C2 (ru) * 1999-05-13 2005-12-27 Фарма Мар, С.А. Композиции и применение ет743 для лечения злокачественных опухолей

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
GB9304589D0 (en) * 1993-03-05 1993-04-21 Erba Carlo Spa Biologically active ureido derivatives useful as antimetastic agents
FR2723947B1 (fr) * 1994-08-31 1996-09-27 Adir Nouveaux composes tetrahydropyraniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US20080306011A1 (en) * 2004-05-26 2008-12-11 National University Corporation Kagawa University Method of Controlling the Proliferation of Vascular Endothelial Cells and Inhibiting Lumen Formation
RU2404995C2 (ru) * 2004-06-23 2010-11-27 Чилдрен'С Хоспитал Энд Рисерч Сентер Эт Окленд Производные полисахаридов и их применение для индуцирования иммунной реакции
US8148335B2 (en) 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy
US20090214439A1 (en) * 2006-03-15 2009-08-27 Trustees Of Tufts College Fluorinated Carbohydrates and Their Use in Tumor Visualization, Tissue Engineering, and Cancer Chemotherapy
KR100780868B1 (ko) 2006-07-10 2007-11-30 부경대학교 산학협력단 항암효과를 나타내는 4급 아미노 글루코사민 화합물
CA2692419C (en) * 2007-07-03 2017-12-05 Children's Hospital & Research Center At Oakland Inhibitors of polysialic acid de-n-acetylase and methods for using the same
WO2009006613A1 (en) * 2007-07-03 2009-01-08 Children's Hospital & Research Center At Oakland Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting
EP2173759A4 (en) * 2007-07-03 2014-01-29 Childrens Hosp & Res Ct Oak OLIGOSIAL INSERTS, PROCESS FOR THEIR PREPARATION AND ITS IMMUNOLOGICAL USE
FR2930943B1 (fr) * 2008-05-07 2011-03-18 Centre Nat Rech Scient Nouvelles utilisations de derives de d-mannopyranose inhibiteurs de l'angiogenese

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4216208A (en) * 1978-07-31 1980-08-05 Proter S.P.A. N-Acyl derivatives of glucosamines having antitumor chemotherapeutic activity
US4647453A (en) * 1984-10-18 1987-03-03 Peritain, Ltd. Treatment for tissue degenerative inflammatory disease
DE3906174A1 (de) * 1989-02-28 1990-08-30 Forschungszentrum Juelich Gmbh Verfahren zur herstellung von d-mannosaminderivaten

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
1. Journal Org. Chem., 1961, т. 26, с. 2455 - 2458. 2. Arg. Biol. Chem., 1969, т. 33, в. 5, с. 748 - 754. 3. Carbohydrates Research, 1974, т. 38, с. 205 - 216. 4. Tetrahedron Letters, 1968, т. 18, с. 2271. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2266734C2 (ru) * 1999-05-13 2005-12-27 Фарма Мар, С.А. Композиции и применение ет743 для лечения злокачественных опухолей

Also Published As

Publication number Publication date
CA2075336A1 (en) 1993-02-07
EP0527042A3 (OSRAM) 1994-01-05
ZA925871B (en) 1993-04-28
GB9116896D0 (en) 1991-09-18
FI923498L (fi) 1993-02-07
KR930004325A (ko) 1993-03-22
TW248564B (OSRAM) 1995-06-01
AU2037492A (en) 1993-02-11
MY108749A (en) 1996-11-30
JPH05208988A (ja) 1993-08-20
NZ243627A (en) 1994-04-27
FI923498A0 (fi) 1992-08-03
IL102500A (en) 1996-01-19
EP0527042A2 (en) 1993-02-10
HU213208B (en) 1997-03-28
HUT62593A (en) 1993-05-28
FI923498A7 (fi) 1993-02-07
MX9204395A (es) 1993-02-01
US5332756A (en) 1994-07-26
HU9202329D0 (en) 1992-10-28
IL102500A0 (en) 1993-01-14
AU646173B2 (en) 1994-02-10

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