RU2070198C1 - Гетероцикленовое соединение, способ его получения и фармацевтическая композиция - Google Patents

Гетероцикленовое соединение, способ его получения и фармацевтическая композиция Download PDF

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Publication number
RU2070198C1
RU2070198C1 SU914895761A SU4895761A RU2070198C1 RU 2070198 C1 RU2070198 C1 RU 2070198C1 SU 914895761 A SU914895761 A SU 914895761A SU 4895761 A SU4895761 A SU 4895761A RU 2070198 C1 RU2070198 C1 RU 2070198C1
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RU
Russia
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formula
methyl
alkyl
substituents
compound
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SU914895761A
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English (en)
Russian (ru)
Inventor
Джеффри Колерик Берд Томас
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Империал Кемикал Индастриз ПЛС
И.С.И.-Фарма
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SU914895761A 1990-06-21 1991-06-20 Гетероцикленовое соединение, способ его получения и фармацевтическая композиция RU2070198C1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP90401758 1990-06-21
EP90401758.9 1990-06-21
EP91400077 1991-01-15
EP91400077.3 1991-01-15

Publications (1)

Publication Number Publication Date
RU2070198C1 true RU2070198C1 (ru) 1996-12-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SU914895761A RU2070198C1 (ru) 1990-06-21 1991-06-20 Гетероцикленовое соединение, способ его получения и фармацевтическая композиция

Country Status (24)

Country Link
US (3) US5217978A (enExample)
EP (1) EP0462812B1 (enExample)
JP (1) JP3112980B2 (enExample)
KR (1) KR920000753A (enExample)
AT (1) ATE131166T1 (enExample)
AU (1) AU640235B2 (enExample)
CA (1) CA2045095A1 (enExample)
CS (1) CS187391A3 (enExample)
DE (1) DE69115134T2 (enExample)
DK (1) DK0462812T3 (enExample)
ES (1) ES2080900T3 (enExample)
FI (1) FI913045A7 (enExample)
GB (1) GB9113166D0 (enExample)
GR (1) GR3018319T3 (enExample)
HU (1) HUT61753A (enExample)
IE (1) IE911853A1 (enExample)
IL (1) IL98382A0 (enExample)
NO (1) NO912410L (enExample)
NZ (1) NZ238467A (enExample)
PL (1) PL290758A1 (enExample)
PT (1) PT98042A (enExample)
RU (1) RU2070198C1 (enExample)
TW (1) TW229156B (enExample)
ZW (1) ZW6991A1 (enExample)

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IE914005A1 (en) * 1990-12-14 1992-06-17 Zeneca Ltd Novel intermediates
US5281720A (en) * 1991-02-28 1994-01-25 Merck Frosst Canada, Inc. Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
US5227399A (en) * 1991-02-28 1993-07-13 Merck Frosst Canada, Inc. Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis
GB9122590D0 (en) * 1991-10-24 1991-12-04 Lilly Industries Ltd Pharmaceutical compounds
GB9300894D0 (en) * 1992-02-07 1993-03-10 Zeneca Ltd Oxime derivatives
CA2094465A1 (en) * 1992-04-23 1993-10-24 Pierre Andre Raymond Bruneau Cycloalkane derivatives
CA2095005A1 (en) * 1992-05-12 1993-11-13 Philip Neil Edwards Hydroxylamine derivatives
CA2095006A1 (en) * 1992-05-12 1993-11-13 Philip Neil Edwards Oxime derivatives
US5308852A (en) * 1992-06-29 1994-05-03 Merck Frosst Canada, Inc. Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis
US5426109A (en) * 1992-08-27 1995-06-20 Merck Frosst Canada, Inc. Phenylnaphthalene hydroxy acids
US5350744A (en) * 1992-08-27 1994-09-27 Merck Frosst Canada, Inc. Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5428060A (en) * 1992-08-27 1995-06-27 Merck Frosst Canada, Inc. Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5252599A (en) * 1992-08-27 1993-10-12 Merck Frosst Canada, Inc. Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis
AU4444393A (en) * 1992-09-01 1994-03-10 Zeneca Limited Pyrrolidine derivatives
EP0586229A1 (en) * 1992-09-01 1994-03-09 Zeneca Limited 3-Hydroxy-3-(subst-akyl)-pyrrolidines as 5-lipoxygenase inhibitors
US5354865A (en) * 1992-09-10 1994-10-11 Abbott Laboratories Phenylmethyl derivatives having lipoxygenase inhibitory activity
IL108187A0 (en) * 1993-01-28 1994-04-12 Zenecca Limited Oxime derivatives
EP0610032A1 (en) * 1993-02-05 1994-08-10 Zeneca Limited Acetanilide derivatives
IL109254A (en) * 1993-04-29 1999-03-12 Zeneca Ltd Tetrahydropyran and tetrahydrofuran ether derivatives their preparation and pharmaceutical compositions comprising them
US5459271A (en) * 1993-07-20 1995-10-17 Merck Frosst Canada, Inc. Arylbicyclooctanes as inhibitors of leukotriene biosynthesis
US5410054A (en) * 1993-07-20 1995-04-25 Merck Frosst Canada, Inc. Heteroaryl quinolines as inhibitors of leukotriene biosynthesis
EP0636624A1 (en) * 1993-07-27 1995-02-01 Zeneca Limited Thiazole derivatives as lipoxygenase inhibitors
ZA945250B (en) * 1993-07-27 1995-01-27 Zeneca Ltd Thiazole derivatives
IL110280A0 (en) * 1993-07-27 1994-10-21 Zeneca Ltd Thiazole derivatives
US5446062A (en) * 1993-11-12 1995-08-29 Abbott Laboratories ((4-alkoxypyran-4-yl) substituted) ether, arylalkyl-, arylalkenyl-, and arylalkynyl)urea inhibitors of 5-lipoxygenase
US5407959A (en) * 1993-11-12 1995-04-18 Abbott Laboratories (Trans-1,4-dialkoxycyclohexyl) substituted arylalkylaryl-arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase
US5552437A (en) * 1994-10-27 1996-09-03 Merck Frosst Canada, Inc. Bisarylcarbinol derivatives as inhibitors of leukotriene biosynthesis
US5891460A (en) * 1995-06-07 1999-04-06 University Of Southern California University Park Campus Method for reducing or preventing post-surgical adhesion formation using ketotifen and analogs thereof
DE69611101T2 (de) * 1995-09-18 2001-04-05 Pfizer Inc., New York Imidazol lipoxygenase inhibitoren
DE19983872T1 (de) * 1998-12-29 2002-02-14 Kimberly Clark Co Wärmeaktivierte Klebstoffe
US6951855B2 (en) 2001-04-23 2005-10-04 Astrazeneca Ab Benzoxazinone derivatives for use in the treatment of angiogenesis
NZ595789A (en) 2009-04-29 2014-05-30 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same

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Also Published As

Publication number Publication date
US5484805A (en) 1996-01-16
AU7815791A (en) 1992-01-02
DE69115134T2 (de) 1996-06-13
JP3112980B2 (ja) 2000-11-27
DE69115134D1 (de) 1996-01-18
AU640235B2 (en) 1993-08-19
PT98042A (pt) 1992-04-30
CS187391A3 (en) 1992-02-19
NZ238467A (en) 1993-08-26
ZW6991A1 (en) 1992-03-25
PL290758A1 (en) 1992-08-24
IE911853A1 (en) 1992-01-01
EP0462812A3 (en) 1992-01-22
JPH04230282A (ja) 1992-08-19
GR3018319T3 (en) 1996-03-31
NO912410D0 (no) 1991-06-20
FI913045A0 (fi) 1991-06-20
EP0462812A2 (en) 1991-12-27
HU912002D0 (en) 1991-12-30
US5359063A (en) 1994-10-25
FI913045L (fi) 1991-12-22
IL98382A0 (en) 1992-07-15
TW229156B (enExample) 1994-09-01
ATE131166T1 (de) 1995-12-15
ES2080900T3 (es) 1996-02-16
CA2045095A1 (en) 1991-12-22
FI913045A7 (fi) 1991-12-22
NO912410L (no) 1991-12-23
EP0462812B1 (en) 1995-12-06
KR920000753A (ko) 1992-01-29
DK0462812T3 (da) 1996-04-22
GB9113166D0 (en) 1991-08-07
HUT61753A (en) 1993-03-01
US5217978A (en) 1993-06-08

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