RU2020112898A - Способ получения фракции лизата тромбоцитов, фракция лизата тромбоцитов и ее применение для лечения расстройств центральной нервной системы - Google Patents
Способ получения фракции лизата тромбоцитов, фракция лизата тромбоцитов и ее применение для лечения расстройств центральной нервной системы Download PDFInfo
- Publication number
- RU2020112898A RU2020112898A RU2020112898A RU2020112898A RU2020112898A RU 2020112898 A RU2020112898 A RU 2020112898A RU 2020112898 A RU2020112898 A RU 2020112898A RU 2020112898 A RU2020112898 A RU 2020112898A RU 2020112898 A RU2020112898 A RU 2020112898A
- Authority
- RU
- Russia
- Prior art keywords
- platelet lysate
- fraction
- disorders
- use according
- kda
- Prior art date
Links
- 239000006166 lysate Substances 0.000 title claims 27
- 238000000034 method Methods 0.000 title claims 6
- 210000003169 central nervous system Anatomy 0.000 title claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims 2
- 208000018737 Parkinson disease Diseases 0.000 claims 4
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 3
- 208000015122 neurodegenerative disease Diseases 0.000 claims 3
- 208000024827 Alzheimer disease Diseases 0.000 claims 2
- 201000011240 Frontotemporal dementia Diseases 0.000 claims 2
- 208000023105 Huntington disease Diseases 0.000 claims 2
- 206010064930 age-related macular degeneration Diseases 0.000 claims 2
- 208000015114 central nervous system disease Diseases 0.000 claims 2
- 208000002780 macular degeneration Diseases 0.000 claims 2
- 201000006417 multiple sclerosis Diseases 0.000 claims 2
- 238000000108 ultra-filtration Methods 0.000 claims 2
- 208000014644 Brain disease Diseases 0.000 claims 1
- 102000008946 Fibrinogen Human genes 0.000 claims 1
- 108010049003 Fibrinogen Proteins 0.000 claims 1
- 206010021143 Hypoxia Diseases 0.000 claims 1
- 208000009829 Lewy Body Disease Diseases 0.000 claims 1
- 201000002832 Lewy body dementia Diseases 0.000 claims 1
- 208000029726 Neurodevelopmental disease Diseases 0.000 claims 1
- 208000018642 Semantic dementia Diseases 0.000 claims 1
- 208000026062 Tissue disease Diseases 0.000 claims 1
- 201000004810 Vascular dementia Diseases 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 230000006931 brain damage Effects 0.000 claims 1
- 231100000874 brain damage Toxicity 0.000 claims 1
- 208000029028 brain injury Diseases 0.000 claims 1
- 210000004289 cerebral ventricle Anatomy 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940012952 fibrinogen Drugs 0.000 claims 1
- 238000005194 fractionation Methods 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 230000007954 hypoxia Effects 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 208000017376 neurovascular disease Diseases 0.000 claims 1
- 239000006228 supernatant Substances 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 210000000211 third ventricle Anatomy 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0644—Platelets; Megakaryocytes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Virology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17306284.5 | 2017-09-27 | ||
| EP17306284 | 2017-09-27 | ||
| PCT/EP2018/076244 WO2019063683A1 (en) | 2017-09-27 | 2018-09-27 | PROCESS FOR THE PREPARATION OF PLATELET LYSATE FRACTION, PLATELET LYSATE FRACTION AND USE THEREOF FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2020112898A true RU2020112898A (ru) | 2021-10-04 |
Family
ID=60083230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2020112898A RU2020112898A (ru) | 2017-09-27 | 2018-09-27 | Способ получения фракции лизата тромбоцитов, фракция лизата тромбоцитов и ее применение для лечения расстройств центральной нервной системы |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230135837A1 (enExample) |
| EP (1) | EP3687554A1 (enExample) |
| JP (1) | JP2020535163A (enExample) |
| CN (1) | CN111107857A (enExample) |
| AU (1) | AU2018343875A1 (enExample) |
| BR (1) | BR112020006316A2 (enExample) |
| CA (1) | CA3076858A1 (enExample) |
| IL (1) | IL273482A (enExample) |
| RU (1) | RU2020112898A (enExample) |
| TW (1) | TW201914595A (enExample) |
| WO (1) | WO2019063683A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108671224B (zh) * | 2011-06-27 | 2022-12-13 | 爱默蕾大学 | 血小板裂解物的组合物、用途和制备 |
| TWI744300B (zh) * | 2016-03-23 | 2021-11-01 | 里爾中央醫學中心 | 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途 |
| US20210236556A1 (en) * | 2020-02-03 | 2021-08-05 | Oklahoma Blood Institute | Preparation of human platelet lysate (hpl) from refrigerated whole blood platelets |
| EP3881858A1 (en) * | 2020-03-20 | 2021-09-22 | Rok Pangersic | Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4815063B2 (ja) * | 2001-04-13 | 2011-11-16 | きみ子 室伏 | 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び／又は生存の促進のための薬剤 |
| SE528214C2 (sv) * | 2005-06-23 | 2006-09-26 | Proliff Ab | Förfarande för framställning av blodplättslysat |
| EP2101806B1 (en) * | 2006-12-14 | 2013-05-01 | NeuroNova AB | Treatment of parkinson's disease or parkinsonian disorders using agents that decrease the activity of the melanocortin 4 receptor |
| EP2389942B1 (en) * | 2010-05-25 | 2013-01-23 | GwoWei Technology Co., Ltd. | Virally-inactivated growth factors-containing platelet lysate depleted of PDGF and VEGF and preparation method thereof |
| US11285100B2 (en) * | 2014-02-20 | 2022-03-29 | Ortho Regenerative Technologies Inc. | Freeze-dried polymer compositions for mixing with platelet rich plasma to form implants for tissue repair and/or compositions for therapeutic intra-articular injections |
| CA3138143A1 (en) * | 2014-05-16 | 2015-11-19 | Mayo Foundation For Medical Education And Research | Cell culture media compositions for primary cells |
-
2018
- 2018-09-26 TW TW107133811A patent/TW201914595A/zh unknown
- 2018-09-27 CA CA3076858A patent/CA3076858A1/en active Pending
- 2018-09-27 JP JP2020517424A patent/JP2020535163A/ja active Pending
- 2018-09-27 US US16/650,070 patent/US20230135837A1/en not_active Abandoned
- 2018-09-27 EP EP18782679.7A patent/EP3687554A1/en not_active Withdrawn
- 2018-09-27 RU RU2020112898A patent/RU2020112898A/ru unknown
- 2018-09-27 BR BR112020006316-9A patent/BR112020006316A2/pt not_active IP Right Cessation
- 2018-09-27 AU AU2018343875A patent/AU2018343875A1/en not_active Abandoned
- 2018-09-27 WO PCT/EP2018/076244 patent/WO2019063683A1/en not_active Ceased
- 2018-09-27 CN CN201880061493.6A patent/CN111107857A/zh active Pending
-
2020
- 2020-03-22 IL IL273482A patent/IL273482A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW201914595A (zh) | 2019-04-16 |
| AU2018343875A1 (en) | 2020-04-16 |
| BR112020006316A2 (pt) | 2020-09-24 |
| US20230135837A1 (en) | 2023-05-04 |
| JP2020535163A (ja) | 2020-12-03 |
| EP3687554A1 (en) | 2020-08-05 |
| IL273482A (en) | 2020-05-31 |
| WO2019063683A1 (en) | 2019-04-04 |
| CA3076858A1 (en) | 2019-04-04 |
| CN111107857A (zh) | 2020-05-05 |
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