CN111107857A - 制备血小板裂解物级分的方法、血小板裂解物级分及其用于治疗中枢神经系统疾病的用途 - Google Patents

制备血小板裂解物级分的方法、血小板裂解物级分及其用于治疗中枢神经系统疾病的用途 Download PDF

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Publication number
CN111107857A
CN111107857A CN201880061493.6A CN201880061493A CN111107857A CN 111107857 A CN111107857 A CN 111107857A CN 201880061493 A CN201880061493 A CN 201880061493A CN 111107857 A CN111107857 A CN 111107857A
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CN
China
Prior art keywords
platelet lysate
fraction
platelet
disease
lysate fraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201880061493.6A
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English (en)
Chinese (zh)
Inventor
D·德沃斯
T·布努夫
J-C·德威德疆
周明礼
F·古埃尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coastal Opal Coast University
Institut National de la Sante et de la Recherche Medicale INSERM
Centre Hospitalier Universitaire de Lille
Universite de Lille
Taipei Medical University TMU
Original Assignee
Coastal Opal Coast University
Institut National de la Sante et de la Recherche Medicale INSERM
Centre Hospitalier Regional Universitaire de Lille CHRU
Universite de Lille
Taipei Medical University TMU
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Application filed by Coastal Opal Coast University, Institut National de la Sante et de la Recherche Medicale INSERM, Centre Hospitalier Regional Universitaire de Lille CHRU, Universite de Lille, Taipei Medical University TMU filed Critical Coastal Opal Coast University
Publication of CN111107857A publication Critical patent/CN111107857A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0644—Platelets; Megakaryocytes

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CN201880061493.6A 2017-09-27 2018-09-27 制备血小板裂解物级分的方法、血小板裂解物级分及其用于治疗中枢神经系统疾病的用途 Pending CN111107857A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17306284.5 2017-09-27
EP17306284 2017-09-27
PCT/EP2018/076244 WO2019063683A1 (en) 2017-09-27 2018-09-27 PROCESS FOR THE PREPARATION OF PLATELET LYSATE FRACTION, PLATELET LYSATE FRACTION AND USE THEREOF FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS

Publications (1)

Publication Number Publication Date
CN111107857A true CN111107857A (zh) 2020-05-05

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Family Applications (1)

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CN201880061493.6A Pending CN111107857A (zh) 2017-09-27 2018-09-27 制备血小板裂解物级分的方法、血小板裂解物级分及其用于治疗中枢神经系统疾病的用途

Country Status (11)

Country Link
US (1) US20230135837A1 (enExample)
EP (1) EP3687554A1 (enExample)
JP (1) JP2020535163A (enExample)
CN (1) CN111107857A (enExample)
AU (1) AU2018343875A1 (enExample)
BR (1) BR112020006316A2 (enExample)
CA (1) CA3076858A1 (enExample)
IL (1) IL273482A (enExample)
RU (1) RU2020112898A (enExample)
TW (1) TW201914595A (enExample)
WO (1) WO2019063683A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108671224A (zh) * 2011-06-27 2018-10-19 爱默蕾大学 血小板裂解物的组合物、用途和制备
CN109310711A (zh) * 2016-03-23 2019-02-05 里尔大学中心医院 血小板沉淀裂解物的制备及其治疗神经系统疾病的用途

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210236556A1 (en) * 2020-02-03 2021-08-05 Oklahoma Blood Institute Preparation of human platelet lysate (hpl) from refrigerated whole blood platelets
EP3881858A1 (en) * 2020-03-20 2021-09-22 Rok Pangersic Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0501462L (sv) * 2005-06-23 2006-09-26 Proliff Ab Förfarande för framställning av blodplättslysat
CN102985101A (zh) * 2010-05-25 2013-03-20 国维联合科技股份有限公司 含有病毒去活化的生长因子且pdgf与vdgf耗尽的血小板裂解物及其制备方法
WO2015123778A1 (en) * 2014-02-20 2015-08-27 Polyvalor, Limited Partnership Freeze-dried polymer compositions for mixing with platelet rich plasma to form implants for tissue repair and/or compositions for therapeutic intra-articular injections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4815063B2 (ja) * 2001-04-13 2011-11-16 きみ子 室伏 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び／又は生存の促進のための薬剤
EP2101806B1 (en) * 2006-12-14 2013-05-01 NeuroNova AB Treatment of parkinson's disease or parkinsonian disorders using agents that decrease the activity of the melanocortin 4 receptor
CA3138143A1 (en) * 2014-05-16 2015-11-19 Mayo Foundation For Medical Education And Research Cell culture media compositions for primary cells

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0501462L (sv) * 2005-06-23 2006-09-26 Proliff Ab Förfarande för framställning av blodplättslysat
CN102985101A (zh) * 2010-05-25 2013-03-20 国维联合科技股份有限公司 含有病毒去活化的生长因子且pdgf与vdgf耗尽的血小板裂解物及其制备方法
WO2015123778A1 (en) * 2014-02-20 2015-08-27 Polyvalor, Limited Partnership Freeze-dried polymer compositions for mixing with platelet rich plasma to form implants for tissue repair and/or compositions for therapeutic intra-articular injections

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHOU ML等: "Tailor-made purified human platelet lysate concentrated in neurotrophins for treatment of Parkinson\'s disease" *
Y C CHOI等: "Effect of platelet lysate on growth and sulfated glycosaminoglycan synthesis in articular chondrocyte cultures" *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108671224A (zh) * 2011-06-27 2018-10-19 爱默蕾大学 血小板裂解物的组合物、用途和制备
CN108671224B (zh) * 2011-06-27 2022-12-13 爱默蕾大学 血小板裂解物的组合物、用途和制备
CN109310711A (zh) * 2016-03-23 2019-02-05 里尔大学中心医院 血小板沉淀裂解物的制备及其治疗神经系统疾病的用途
CN109310711B (zh) * 2016-03-23 2022-06-10 里尔大学中心医院 血小板沉淀裂解物的制备及其治疗神经系统疾病的用途

Also Published As

Publication number Publication date
TW201914595A (zh) 2019-04-16
AU2018343875A1 (en) 2020-04-16
BR112020006316A2 (pt) 2020-09-24
RU2020112898A (ru) 2021-10-04
US20230135837A1 (en) 2023-05-04
JP2020535163A (ja) 2020-12-03
EP3687554A1 (en) 2020-08-05
IL273482A (en) 2020-05-31
WO2019063683A1 (en) 2019-04-04
CA3076858A1 (en) 2019-04-04

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