TW201914595A - 製備血小板裂解物組分的方法、血小板裂解物組分及其用於治療中樞神經系統疾病的用途 - Google Patents

製備血小板裂解物組分的方法、血小板裂解物組分及其用於治療中樞神經系統疾病的用途 Download PDF

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Publication number
TW201914595A
TW201914595A TW107133811A TW107133811A TW201914595A TW 201914595 A TW201914595 A TW 201914595A TW 107133811 A TW107133811 A TW 107133811A TW 107133811 A TW107133811 A TW 107133811A TW 201914595 A TW201914595 A TW 201914595A
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TW
Taiwan
Prior art keywords
platelet lysate
platelet
component
kda
disease
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TW107133811A
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English (en)
Chinese (zh)
Inventor
大衛 戴弗斯
台瑞 白
珍克里斯托夫 德威簡
周明莉
弗羅爾 古埃爾
Original Assignee
法國里爾中央醫學中心
法國里爾大學
法國濱海大學
法國國家健康及醫學研究中心
臺北醫學大學
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Application filed by 法國里爾中央醫學中心, 法國里爾大學, 法國濱海大學, 法國國家健康及醫學研究中心, 臺北醫學大學 filed Critical 法國里爾中央醫學中心
Publication of TW201914595A publication Critical patent/TW201914595A/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/19Platelets; Megacaryocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0644Platelets; Megakaryocytes

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
TW107133811A 2017-09-27 2018-09-26 製備血小板裂解物組分的方法、血小板裂解物組分及其用於治療中樞神經系統疾病的用途 TW201914595A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17306284.5 2017-09-27
EP17306284 2017-09-27

Publications (1)

Publication Number Publication Date
TW201914595A true TW201914595A (zh) 2019-04-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
TW107133811A TW201914595A (zh) 2017-09-27 2018-09-26 製備血小板裂解物組分的方法、血小板裂解物組分及其用於治療中樞神經系統疾病的用途

Country Status (11)

Country Link
US (1) US20230135837A1 (enExample)
EP (1) EP3687554A1 (enExample)
JP (1) JP2020535163A (enExample)
CN (1) CN111107857A (enExample)
AU (1) AU2018343875A1 (enExample)
BR (1) BR112020006316A2 (enExample)
CA (1) CA3076858A1 (enExample)
IL (1) IL273482A (enExample)
RU (1) RU2020112898A (enExample)
TW (1) TW201914595A (enExample)
WO (1) WO2019063683A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108671224B (zh) * 2011-06-27 2022-12-13 爱默蕾大学 血小板裂解物的组合物、用途和制备
TWI744300B (zh) * 2016-03-23 2021-11-01 里爾中央醫學中心 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途
US20210236556A1 (en) * 2020-02-03 2021-08-05 Oklahoma Blood Institute Preparation of human platelet lysate (hpl) from refrigerated whole blood platelets
EP3881858A1 (en) * 2020-03-20 2021-09-22 Rok Pangersic Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4815063B2 (ja) * 2001-04-13 2011-11-16 きみ子 室伏 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び/又は生存の促進のための薬剤
SE528214C2 (sv) * 2005-06-23 2006-09-26 Proliff Ab Förfarande för framställning av blodplättslysat
EP2101806B1 (en) * 2006-12-14 2013-05-01 NeuroNova AB Treatment of parkinson's disease or parkinsonian disorders using agents that decrease the activity of the melanocortin 4 receptor
EP2389942B1 (en) * 2010-05-25 2013-01-23 GwoWei Technology Co., Ltd. Virally-inactivated growth factors-containing platelet lysate depleted of PDGF and VEGF and preparation method thereof
US11285100B2 (en) * 2014-02-20 2022-03-29 Ortho Regenerative Technologies Inc. Freeze-dried polymer compositions for mixing with platelet rich plasma to form implants for tissue repair and/or compositions for therapeutic intra-articular injections
CA3138143A1 (en) * 2014-05-16 2015-11-19 Mayo Foundation For Medical Education And Research Cell culture media compositions for primary cells

Also Published As

Publication number Publication date
AU2018343875A1 (en) 2020-04-16
BR112020006316A2 (pt) 2020-09-24
RU2020112898A (ru) 2021-10-04
US20230135837A1 (en) 2023-05-04
JP2020535163A (ja) 2020-12-03
EP3687554A1 (en) 2020-08-05
IL273482A (en) 2020-05-31
WO2019063683A1 (en) 2019-04-04
CA3076858A1 (en) 2019-04-04
CN111107857A (zh) 2020-05-05

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