JP2020535163A - 血小板溶解物画分を調製するための方法、血小板溶解物画分、及び中枢神経系の障害を処置するためのその使用 - Google Patents

血小板溶解物画分を調製するための方法、血小板溶解物画分、及び中枢神経系の障害を処置するためのその使用 Download PDF

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Publication number
JP2020535163A
JP2020535163A JP2020517424A JP2020517424A JP2020535163A JP 2020535163 A JP2020535163 A JP 2020535163A JP 2020517424 A JP2020517424 A JP 2020517424A JP 2020517424 A JP2020517424 A JP 2020517424A JP 2020535163 A JP2020535163 A JP 2020535163A
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Prior art keywords
platelet lysate
fraction
platelet
kda
disorders
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Pending
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JP2020517424A
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English (en)
Japanese (ja)
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JP2020535163A5 (enExample
Inventor
ダヴィド・ドゥヴォス
ティエリー・ビュルヌーフ
ジャン−クリストフ・ドゥヴジャン
ミン−リ・チョウ
フロール・グエル
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Institut National de la Sante et de la Recherche Medicale INSERM
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Institut National de la Sante et de la Recherche Medicale INSERM
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Publication of JP2020535163A publication Critical patent/JP2020535163A/ja
Publication of JP2020535163A5 publication Critical patent/JP2020535163A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0644—Platelets; Megakaryocytes

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2020517424A 2017-09-27 2018-09-27 血小板溶解物画分を調製するための方法、血小板溶解物画分、及び中枢神経系の障害を処置するためのその使用 Pending JP2020535163A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17306284.5 2017-09-27
EP17306284 2017-09-27
PCT/EP2018/076244 WO2019063683A1 (en) 2017-09-27 2018-09-27 PROCESS FOR THE PREPARATION OF PLATELET LYSATE FRACTION, PLATELET LYSATE FRACTION AND USE THEREOF FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS

Publications (2)

Publication Number Publication Date
JP2020535163A true JP2020535163A (ja) 2020-12-03
JP2020535163A5 JP2020535163A5 (enExample) 2021-10-14

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JP2020517424A Pending JP2020535163A (ja) 2017-09-27 2018-09-27 血小板溶解物画分を調製するための方法、血小板溶解物画分、及び中枢神経系の障害を処置するためのその使用

Country Status (11)

Country Link
US (1) US20230135837A1 (enExample)
EP (1) EP3687554A1 (enExample)
JP (1) JP2020535163A (enExample)
CN (1) CN111107857A (enExample)
AU (1) AU2018343875A1 (enExample)
BR (1) BR112020006316A2 (enExample)
CA (1) CA3076858A1 (enExample)
IL (1) IL273482A (enExample)
RU (1) RU2020112898A (enExample)
TW (1) TW201914595A (enExample)
WO (1) WO2019063683A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108671224B (zh) * 2011-06-27 2022-12-13 爱默蕾大学 血小板裂解物的组合物、用途和制备
TWI744300B (zh) * 2016-03-23 2021-11-01 里爾中央醫學中心 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途
US20210236556A1 (en) * 2020-02-03 2021-08-05 Oklahoma Blood Institute Preparation of human platelet lysate (hpl) from refrigerated whole blood platelets
EP3881858A1 (en) * 2020-03-20 2021-09-22 Rok Pangersic Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002308779A (ja) * 2001-04-13 2002-10-23 Gencom Co 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び／又は生存の促進のための薬剤
JP2010513230A (ja) * 2006-12-14 2010-04-30 ニューロノバ エービー メラノコルチン４レセプターの活性を低下させる薬剤を使用した、神経系の疾患または損傷の処置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE528214C2 (sv) * 2005-06-23 2006-09-26 Proliff Ab Förfarande för framställning av blodplättslysat
EP2389942B1 (en) * 2010-05-25 2013-01-23 GwoWei Technology Co., Ltd. Virally-inactivated growth factors-containing platelet lysate depleted of PDGF and VEGF and preparation method thereof
US11285100B2 (en) * 2014-02-20 2022-03-29 Ortho Regenerative Technologies Inc. Freeze-dried polymer compositions for mixing with platelet rich plasma to form implants for tissue repair and/or compositions for therapeutic intra-articular injections
CA3138143A1 (en) * 2014-05-16 2015-11-19 Mayo Foundation For Medical Education And Research Cell culture media compositions for primary cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002308779A (ja) * 2001-04-13 2002-10-23 Gencom Co 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び／又は生存の促進のための薬剤
JP2010513230A (ja) * 2006-12-14 2010-04-30 ニューロノバ エービー メラノコルチン４レセプターの活性を低下させる薬剤を使用した、神経系の疾患または損傷の処置

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"グリア細胞が脳を外傷から保護するメカニズムの解明", 国立大学法人山梨大学 プレスリリース, JPN6022027112, 8 May 2017 (2017-05-08), ISSN: 0005127727 *
CHOI YC: "Effect of platelet lysate on growth and sulfated glycosaminoglycan synthesis in articular chondrocyt", ARTHRITIS RHEUM, vol. 23巻2号, JPN6022027108, 1980, pages 220 - 224, ISSN: 0005127725 *
HELDIN CH: "Partial purification and characterization of platelet factors stimulating the multiplication of norm", EXP CELL RES, vol. 109巻2号, JPN6022027111, 1977, pages 429 - 437, ISSN: 0005127726 *

Also Published As

Publication number Publication date
TW201914595A (zh) 2019-04-16
AU2018343875A1 (en) 2020-04-16
BR112020006316A2 (pt) 2020-09-24
RU2020112898A (ru) 2021-10-04
US20230135837A1 (en) 2023-05-04
EP3687554A1 (en) 2020-08-05
IL273482A (en) 2020-05-31
WO2019063683A1 (en) 2019-04-04
CA3076858A1 (en) 2019-04-04
CN111107857A (zh) 2020-05-05

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