RU2019116069A - Новые биомаркеры старения кожи человека - Google Patents
Новые биомаркеры старения кожи человека Download PDFInfo
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- RU2019116069A RU2019116069A RU2019116069A RU2019116069A RU2019116069A RU 2019116069 A RU2019116069 A RU 2019116069A RU 2019116069 A RU2019116069 A RU 2019116069A RU 2019116069 A RU2019116069 A RU 2019116069A RU 2019116069 A RU2019116069 A RU 2019116069A
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- hmgn1
- tubb3
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- 230000009759 skin aging Effects 0.000 title claims 4
- 239000000090 biomarker Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 claims 54
- 102000004169 proteins and genes Human genes 0.000 claims 29
- 210000003491 skin Anatomy 0.000 claims 21
- 108700039143 HMGA2 Proteins 0.000 claims 12
- 102100028999 High mobility group protein HMGI-C Human genes 0.000 claims 12
- 101150073387 Hmga2 gene Proteins 0.000 claims 12
- 101000866795 Homo sapiens Non-histone chromosomal protein HMG-14 Proteins 0.000 claims 12
- 101000713575 Homo sapiens Tubulin beta-3 chain Proteins 0.000 claims 12
- 102100031353 Non-histone chromosomal protein HMG-14 Human genes 0.000 claims 12
- 102100036790 Tubulin beta-3 chain Human genes 0.000 claims 12
- 238000000034 method Methods 0.000 claims 12
- 230000032683 aging Effects 0.000 claims 9
- -1 NEB Proteins 0.000 claims 7
- 102100036659 26S proteasome non-ATPase regulatory subunit 9 Human genes 0.000 claims 6
- 102100039377 28 kDa heat- and acid-stable phosphoprotein Human genes 0.000 claims 6
- 102000003741 Actin-related protein 3 Human genes 0.000 claims 6
- 108090000104 Actin-related protein 3 Proteins 0.000 claims 6
- 102100032559 Clathrin light chain B Human genes 0.000 claims 6
- 102100027563 Cytochrome c oxidase subunit 5A, mitochondrial Human genes 0.000 claims 6
- 102100023078 Early endosome antigen 1 Human genes 0.000 claims 6
- 102100029009 High mobility group protein HMG-I/HMG-Y Human genes 0.000 claims 6
- 102100021639 Histone H2B type 1-K Human genes 0.000 claims 6
- 101001136710 Homo sapiens 26S proteasome non-ATPase regulatory subunit 9 Proteins 0.000 claims 6
- 101001035654 Homo sapiens 28 kDa heat- and acid-stable phosphoprotein Proteins 0.000 claims 6
- 101000942271 Homo sapiens Clathrin light chain B Proteins 0.000 claims 6
- 101000725076 Homo sapiens Cytochrome c oxidase subunit 5A, mitochondrial Proteins 0.000 claims 6
- 101001050162 Homo sapiens Early endosome antigen 1 Proteins 0.000 claims 6
- 101000986380 Homo sapiens High mobility group protein HMG-I/HMG-Y Proteins 0.000 claims 6
- 101000898898 Homo sapiens Histone H2B type 1-K Proteins 0.000 claims 6
- 101001042036 Homo sapiens Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Proteins 0.000 claims 6
- 101000942713 Homo sapiens Liprin-alpha-2 Proteins 0.000 claims 6
- 101001027945 Homo sapiens Metallothionein-1E Proteins 0.000 claims 6
- 101001000104 Homo sapiens Myosin-11 Proteins 0.000 claims 6
- 101000866805 Homo sapiens Non-histone chromosomal protein HMG-17 Proteins 0.000 claims 6
- 101001133656 Homo sapiens Plasminogen activator inhibitor 1 RNA-binding protein Proteins 0.000 claims 6
- 101000596119 Homo sapiens Plastin-3 Proteins 0.000 claims 6
- 101000980965 Homo sapiens Protein CDV3 homolog Proteins 0.000 claims 6
- 101000738322 Homo sapiens Prothymosin alpha Proteins 0.000 claims 6
- 101000700735 Homo sapiens Serine/arginine-rich splicing factor 7 Proteins 0.000 claims 6
- 101000831940 Homo sapiens Stathmin Proteins 0.000 claims 6
- 101000653663 Homo sapiens T-complex protein 1 subunit epsilon Proteins 0.000 claims 6
- 101000658138 Homo sapiens Thymosin beta-10 Proteins 0.000 claims 6
- 101000658157 Homo sapiens Thymosin beta-4 Proteins 0.000 claims 6
- 101000788845 Homo sapiens Zinc finger CCCH domain-containing protein 11A Proteins 0.000 claims 6
- 102100021332 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Human genes 0.000 claims 6
- 102100032894 Liprin-alpha-2 Human genes 0.000 claims 6
- 102100037510 Metallothionein-1E Human genes 0.000 claims 6
- 102100036639 Myosin-11 Human genes 0.000 claims 6
- 102100031346 Non-histone chromosomal protein HMG-17 Human genes 0.000 claims 6
- 102100034055 Plasminogen activator inhibitor 1 RNA-binding protein Human genes 0.000 claims 6
- 102100035220 Plastin-3 Human genes 0.000 claims 6
- 102100024920 Prefoldin subunit 2 Human genes 0.000 claims 6
- 102100024449 Protein CDV3 homolog Human genes 0.000 claims 6
- 102100037925 Prothymosin alpha Human genes 0.000 claims 6
- 102100029287 Serine/arginine-rich splicing factor 7 Human genes 0.000 claims 6
- 102100024237 Stathmin Human genes 0.000 claims 6
- 102100029886 T-complex protein 1 subunit epsilon Human genes 0.000 claims 6
- 102100034998 Thymosin beta-10 Human genes 0.000 claims 6
- 102100035000 Thymosin beta-4 Human genes 0.000 claims 6
- OKKRPWIIYQTPQF-UHFFFAOYSA-N Trimethylolpropane trimethacrylate Chemical compound CC(=C)C(=O)OCC(CC)(COC(=O)C(C)=C)COC(=O)C(C)=C OKKRPWIIYQTPQF-UHFFFAOYSA-N 0.000 claims 6
- 102100025402 Zinc finger CCCH domain-containing protein 11A Human genes 0.000 claims 6
- 108010075843 alpha-2-HS-Glycoprotein Proteins 0.000 claims 6
- 102000012005 alpha-2-HS-Glycoprotein Human genes 0.000 claims 6
- 239000000126 substance Substances 0.000 claims 6
- LTPSRQRIPCVMKQ-UHFFFAOYSA-N 2-amino-5-methylbenzenesulfonic acid Chemical compound CC1=CC=C(N)C(S(O)(=O)=O)=C1 LTPSRQRIPCVMKQ-UHFFFAOYSA-N 0.000 claims 5
- 102100032303 26S proteasome non-ATPase regulatory subunit 2 Human genes 0.000 claims 5
- 102100023679 40S ribosomal protein S28 Human genes 0.000 claims 5
- 102100024442 60S ribosomal protein L13 Human genes 0.000 claims 5
- 101100339431 Arabidopsis thaliana HMGB2 gene Proteins 0.000 claims 5
- 102100025580 Calmodulin-1 Human genes 0.000 claims 5
- 102000058063 Glucose Transporter Type 1 Human genes 0.000 claims 5
- 108700010013 HMGB1 Proteins 0.000 claims 5
- 101150021904 HMGB1 gene Proteins 0.000 claims 5
- 102100037907 High mobility group protein B1 Human genes 0.000 claims 5
- 101000590272 Homo sapiens 26S proteasome non-ATPase regulatory subunit 2 Proteins 0.000 claims 5
- 101000691550 Homo sapiens 39S ribosomal protein L13, mitochondrial Proteins 0.000 claims 5
- 101000623076 Homo sapiens 40S ribosomal protein S28 Proteins 0.000 claims 5
- 101001118201 Homo sapiens 60S ribosomal protein L13 Proteins 0.000 claims 5
- 101000984164 Homo sapiens Calmodulin-1 Proteins 0.000 claims 5
- 101001076613 Homo sapiens Immortalization up-regulated protein Proteins 0.000 claims 5
- 101000961149 Homo sapiens Immunoglobulin heavy constant gamma 4 Proteins 0.000 claims 5
- 101001027938 Homo sapiens Metallothionein-1G Proteins 0.000 claims 5
- 101001082207 Homo sapiens Parathymosin Proteins 0.000 claims 5
- 101001116674 Homo sapiens Prefoldin subunit 2 Proteins 0.000 claims 5
- 101000730802 Homo sapiens Prefoldin subunit 6 Proteins 0.000 claims 5
- 101000611053 Homo sapiens Proteasome subunit beta type-2 Proteins 0.000 claims 5
- 101000837067 Homo sapiens SH3 domain-binding glutamic acid-rich-like protein 3 Proteins 0.000 claims 5
- 101000832685 Homo sapiens Small ubiquitin-related modifier 2 Proteins 0.000 claims 5
- 101000587717 Homo sapiens Sulfide:quinone oxidoreductase, mitochondrial Proteins 0.000 claims 5
- 101000830781 Homo sapiens Tropomyosin alpha-4 chain Proteins 0.000 claims 5
- 101000806601 Homo sapiens V-type proton ATPase catalytic subunit A Proteins 0.000 claims 5
- 102100025886 Immortalization up-regulated protein Human genes 0.000 claims 5
- 102100039347 Immunoglobulin heavy constant gamma 4 Human genes 0.000 claims 5
- 102100037512 Metallothionein-1G Human genes 0.000 claims 5
- 102100027370 Parathymosin Human genes 0.000 claims 5
- 102100032926 Prefoldin subunit 6 Human genes 0.000 claims 5
- 102100040400 Proteasome subunit beta type-2 Human genes 0.000 claims 5
- 102100028643 SH3 domain-binding glutamic acid-rich-like protein 3 Human genes 0.000 claims 5
- 108091006296 SLC2A1 Proteins 0.000 claims 5
- 102100024542 Small ubiquitin-related modifier 2 Human genes 0.000 claims 5
- 102100031138 Sulfide:quinone oxidoreductase, mitochondrial Human genes 0.000 claims 5
- 102100024944 Tropomyosin alpha-4 chain Human genes 0.000 claims 5
- 102100037466 V-type proton ATPase catalytic subunit A Human genes 0.000 claims 5
- 102100030943 Glutathione S-transferase P Human genes 0.000 claims 4
- 101001010139 Homo sapiens Glutathione S-transferase P Proteins 0.000 claims 4
- 102100024341 10 kDa heat shock protein, mitochondrial Human genes 0.000 claims 3
- 102100026357 40S ribosomal protein S13 Human genes 0.000 claims 3
- 102100023541 Glutathione S-transferase omega-1 Human genes 0.000 claims 3
- 101000980303 Homo sapiens 10 kDa heat shock protein, mitochondrial Proteins 0.000 claims 3
- 101000718313 Homo sapiens 40S ribosomal protein S13 Proteins 0.000 claims 3
- 101000906386 Homo sapiens Glutathione S-transferase omega-1 Proteins 0.000 claims 3
- 101001098824 Homo sapiens Protein disulfide-isomerase A4 Proteins 0.000 claims 3
- 102100037089 Protein disulfide-isomerase A4 Human genes 0.000 claims 3
- 239000003446 ligand Substances 0.000 claims 3
- 102100025514 ATP-dependent 6-phosphofructokinase, platelet type Human genes 0.000 claims 2
- 101710106492 Acyl-CoA-binding protein Proteins 0.000 claims 2
- 101710169323 Acyl-CoA-binding protein homolog Proteins 0.000 claims 2
- 102100030291 Cornifin-B Human genes 0.000 claims 2
- 102100033325 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Human genes 0.000 claims 2
- 102100031000 Hepatoma-derived growth factor Human genes 0.000 claims 2
- 101000693765 Homo sapiens ATP-dependent 6-phosphofructokinase, platelet type Proteins 0.000 claims 2
- 101000702152 Homo sapiens Cornifin-B Proteins 0.000 claims 2
- 101000926793 Homo sapiens Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Proteins 0.000 claims 2
- 101001090050 Homo sapiens Thioredoxin-dependent peroxide reductase, mitochondrial Proteins 0.000 claims 2
- 101000795292 Homo sapiens Tripartite motif-containing protein 6 Proteins 0.000 claims 2
- 102100031269 Putative peripheral benzodiazepine receptor-related protein Human genes 0.000 claims 2
- 101000805921 Strongylocentrotus purpuratus Upstream stimulatory factor Proteins 0.000 claims 2
- 102100034769 Thioredoxin-dependent peroxide reductase, mitochondrial Human genes 0.000 claims 2
- 102100029673 Tripartite motif-containing protein 6 Human genes 0.000 claims 2
- 101000671634 Xenopus borealis Upstream stimulatory factor 1 Proteins 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 108010052188 hepatoma-derived growth factor Proteins 0.000 claims 2
- 210000002510 keratinocyte Anatomy 0.000 claims 2
- 102100036846 C-C motif chemokine 21 Human genes 0.000 claims 1
- 101000713085 Homo sapiens C-C motif chemokine 21 Proteins 0.000 claims 1
- 101000589870 Homo sapiens Prostaglandin reductase 3 Proteins 0.000 claims 1
- 101000635777 Homo sapiens Receptor-transporting protein 4 Proteins 0.000 claims 1
- 101150036282 Pfdn2 gene Proteins 0.000 claims 1
- 102100032255 Prostaglandin reductase 3 Human genes 0.000 claims 1
- 102100030854 Receptor-transporting protein 4 Human genes 0.000 claims 1
- 101100243555 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GIM4 gene Proteins 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6881—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16306561 | 2016-11-25 | ||
| EP16306561.8 | 2016-11-25 | ||
| PCT/EP2017/080414 WO2018096117A1 (en) | 2016-11-25 | 2017-11-24 | New biomarkers of human skin aging |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2019116069A true RU2019116069A (ru) | 2020-12-25 |
Family
ID=57517827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019116069A RU2019116069A (ru) | 2016-11-25 | 2017-11-24 | Новые биомаркеры старения кожи человека |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210109111A1 (enExample) |
| EP (1) | EP3545301A1 (enExample) |
| JP (1) | JP7115756B2 (enExample) |
| CN (1) | CN110268263B (enExample) |
| CA (1) | CA3041959A1 (enExample) |
| RU (1) | RU2019116069A (enExample) |
| WO (1) | WO2018096117A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3803415A1 (en) * | 2018-06-04 | 2021-04-14 | Avon Products, Inc. | Protein biomarkers for identifying and treating aging skin and skin conditions |
| JP7633003B2 (ja) * | 2019-11-29 | 2025-02-19 | ポーラ化成工業株式会社 | 抗老化成分のスクリーニング方法 |
| WO2023090901A1 (ko) * | 2021-11-18 | 2023-05-25 | 의료법인 성광의료재단 | 기계 학습을 이용한 세포 노화의 마커를 선별하는 방법, 세포 노화 바이오 마커, 및 이를 이용한 세놀리틱 제제를 스크리닝 하는 방법 |
| US20230240960A1 (en) * | 2022-01-07 | 2023-08-03 | Revela, Inc | Compositions, formulations, and methods for skin treatment |
| JP2023130972A (ja) * | 2022-03-08 | 2023-09-21 | 株式会社 資生堂 | 黄ぐすみ抑制方法、黄ぐすみ抑制剤のスクリーニング方法、及び黄ぐすみ感受性の評価方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001249098A1 (en) | 2000-03-10 | 2001-09-24 | Lifespan Biosciences, Inc. | Nucleic acid sequences associated with aging, particularly skin aging |
| DE10100121A1 (de) * | 2001-01-03 | 2002-08-01 | Henkel Kgaa | Verfahren zur Bestimmung des Hautstreß oder der Hautalterung in vitro |
| WO2004061456A2 (de) * | 2003-01-03 | 2004-07-22 | Alcedo Biotech Gmbh | Verwendungen von hmgb, hmgn, hmga proteinen |
| WO2004083398A2 (en) * | 2003-03-17 | 2004-09-30 | The Government Of The United States Of America As Represented By The Secretary Of Department Of Health And Human Services | Therapeutic uses of hmgn1 and hmgn2 |
| CN101248192B (zh) * | 2005-08-23 | 2013-02-20 | 株式会社芳珂 | 皮肤老化标记物及其利用技术 |
| US8859021B2 (en) * | 2007-05-14 | 2014-10-14 | Sytheon | Skin appearance through gene manipulation |
| KR100999261B1 (ko) * | 2007-10-09 | 2010-12-07 | (주)아모레퍼시픽 | 여성호르몬 결핍으로 초래되는 여성 피부의 노화 억제제 스크리닝 방법 |
| FR2925313A1 (fr) * | 2007-12-19 | 2009-06-26 | Oreal | Utilisation cosmetique de proteines de type plakoglobine |
| US20120034613A1 (en) * | 2010-08-03 | 2012-02-09 | Nse Products, Inc. | Apparatus and Method for Testing Relationships Between Gene Expression and Physical Appearance of Skin |
| EP2704728A4 (en) * | 2011-05-03 | 2015-04-22 | Dermachip Inc | EXPRESSION SIGNATURES OF AGENTS ASSOCIATED WITH SKIN AGING AND GEN NETWORKS |
| JP6336565B2 (ja) * | 2013-03-15 | 2018-06-06 | ザ プロクター アンド ギャンブル カンパニー | 微生物からの自然防御の客観的尺度として皮膚から抗微生物ペプチドを測定するための非侵襲的方法 |
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2017
- 2017-11-24 CA CA3041959A patent/CA3041959A1/en active Pending
- 2017-11-24 WO PCT/EP2017/080414 patent/WO2018096117A1/en not_active Ceased
- 2017-11-24 JP JP2019528092A patent/JP7115756B2/ja active Active
- 2017-11-24 CN CN201780072821.8A patent/CN110268263B/zh not_active Expired - Fee Related
- 2017-11-24 US US16/464,517 patent/US20210109111A1/en not_active Abandoned
- 2017-11-24 EP EP17801484.1A patent/EP3545301A1/en not_active Withdrawn
- 2017-11-24 RU RU2019116069A patent/RU2019116069A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018096117A1 (en) | 2018-05-31 |
| CN110268263A (zh) | 2019-09-20 |
| JP7115756B2 (ja) | 2022-08-09 |
| US20210109111A1 (en) | 2021-04-15 |
| CA3041959A1 (en) | 2018-05-31 |
| JP2020502498A (ja) | 2020-01-23 |
| CN110268263B (zh) | 2022-07-19 |
| EP3545301A1 (en) | 2019-10-02 |
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