RU2019111101A3 - - Google Patents

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Publication number
RU2019111101A3
RU2019111101A3 RU2019111101A RU2019111101A RU2019111101A3 RU 2019111101 A3 RU2019111101 A3 RU 2019111101A3 RU 2019111101 A RU2019111101 A RU 2019111101A RU 2019111101 A RU2019111101 A RU 2019111101A RU 2019111101 A3 RU2019111101 A3 RU 2019111101A3
Authority
RU
Russia
Application number
RU2019111101A
Other languages
Russian (ru)
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RU2019111101A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2019111101A publication Critical patent/RU2019111101A/ru
Publication of RU2019111101A3 publication Critical patent/RU2019111101A3/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C07J71/0047—Nitrogen only at position 2(3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2019111101A 2016-10-14 2017-10-13 Структуры и механизм для дизайна высокоактивных глюкокортикоидов RU2019111101A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662408314P 2016-10-14 2016-10-14
US62/408,314 2016-10-14
PCT/US2017/056447 WO2018071736A1 (en) 2016-10-14 2017-10-13 Structures and mechanism for the design of highly potent glucocorticoids

Publications (2)

Publication Number Publication Date
RU2019111101A RU2019111101A (ru) 2020-11-16
RU2019111101A3 true RU2019111101A3 (enExample) 2020-11-27

Family

ID=61906432

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2019111101A RU2019111101A (ru) 2016-10-14 2017-10-13 Структуры и механизм для дизайна высокоактивных глюкокортикоидов

Country Status (12)

Country Link
US (1) US10954265B2 (enExample)
EP (1) EP3525870B1 (enExample)
JP (2) JP7146750B2 (enExample)
KR (1) KR102497070B1 (enExample)
CN (1) CN110382033B (enExample)
ES (1) ES2945983T3 (enExample)
MA (1) MA46539A (enExample)
PH (1) PH12019500801A1 (enExample)
RU (1) RU2019111101A (enExample)
SG (1) SG11201903209TA (enExample)
WO (1) WO2018071736A1 (enExample)
ZA (1) ZA201902595B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024396409A1 (en) * 2023-12-08 2026-07-09 Zhejiang Palo Alto Pharmaceuticals, Inc. High-efficacy glucocorticoid polymorph, preparation method therefor, and use thereof
WO2025157225A1 (zh) * 2024-01-24 2025-07-31 浙江柏拉阿图医药科技有限公司 一种高效力糖皮质激素化合物及其制备和用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK66202C (da) 1945-03-03 1948-01-12 Danske Securitas As Kodekontakt til elektriske Alarmanlæg.
DK71662C (da) 1946-09-05 1950-11-06 Ingenioer Frank Broadbent Tørrecentrifuge.
US4049813A (en) 1976-07-15 1977-09-20 Sandoz, Inc. Substituted isoxazolo pyridinones
US5837698A (en) * 1996-05-02 1998-11-17 G. D. Searle & Co. Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs
WO2002102807A1 (en) 2001-06-14 2002-12-27 Banyu Pharmaceutical Co., Ltd. Novel isoxazolopyridone derivatives and use thereof
GB0119911D0 (en) 2001-08-15 2001-10-10 Novartis Ag Organic Compounds
KR20060118536A (ko) * 2003-11-13 2006-11-23 콤비네이토릭스, 인코포레이티드 면역염증성 질환의 치료 방법 및 시약
KR20080039442A (ko) * 2005-09-02 2008-05-07 니콕스 에스. 에이. 스테로이드 니트록시 유도체들
CN1813768A (zh) * 2005-11-18 2006-08-09 成都力思特制药股份有限公司 治疗呼吸系统疾病的药用组合物及其在制药中的应用
MX2010003698A (es) * 2007-10-04 2010-04-21 Astrazeneca Ab Compuestos de [3,2-c]pirazol esteroides con actividad glucocorticoide.
US20110160167A1 (en) * 2007-12-20 2011-06-30 Astrazeneca Ab Steroid Derivatives Acting As Glucocorticosteroid Receptor Agonists
US8173670B2 (en) 2009-01-13 2012-05-08 Van Andel Research Institute Methods of using substituted isoxazolo pyridinones as dissociated glucocorticoids
UY32520A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
UY32523A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32525A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
TW201111392A (en) * 2009-06-16 2011-04-01 Schering Corp Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof
HK1222565A1 (zh) * 2013-09-25 2017-07-07 范安德尔研究所 高效糖皮質激素
TWI695831B (zh) * 2014-09-13 2020-06-11 香港商南北兄弟藥業投資有限公司 Crth2拮抗劑化合物及其用途

Also Published As

Publication number Publication date
KR20190068577A (ko) 2019-06-18
WO2018071736A9 (en) 2019-05-23
CN110382033B (zh) 2022-04-15
RU2019111101A (ru) 2020-11-16
ES2945983T3 (es) 2023-07-11
JP2022132464A (ja) 2022-09-08
EP3525870A4 (en) 2020-04-29
CN110382033A (zh) 2019-10-25
US20190263853A1 (en) 2019-08-29
JP2019532071A (ja) 2019-11-07
US10954265B2 (en) 2021-03-23
EP3525870B1 (en) 2023-05-10
WO2018071736A1 (en) 2018-04-19
KR102497070B1 (ko) 2023-02-06
JP7146750B2 (ja) 2022-10-04
SG11201903209TA (en) 2019-05-30
EP3525870A1 (en) 2019-08-21
ZA201902595B (en) 2021-04-28
PH12019500801A1 (en) 2019-11-11
MA46539A (fr) 2019-08-21

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