RU2018140056A - Композиции и способы с использованием т-клеток с химерным рецептором аллоантигена - Google Patents

Композиции и способы с использованием т-клеток с химерным рецептором аллоантигена Download PDF

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RU2018140056A
RU2018140056A RU2018140056A RU2018140056A RU2018140056A RU 2018140056 A RU2018140056 A RU 2018140056A RU 2018140056 A RU2018140056 A RU 2018140056A RU 2018140056 A RU2018140056 A RU 2018140056A RU 2018140056 A RU2018140056 A RU 2018140056A
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acid sequence
nucleic acid
isolated
callar
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RU2018140056A
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RU2018140056A3 (enExample
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Майкл К. Майлон
Валдер АРРУДА
Сара РИЧМАН
Бенджамин СЕЙМЕЛСОН-ДЖОУНЗ
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Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
Дзе Чилдрен'З Хоспитал Оф Филадельфия
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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RU2018140056A 2016-04-15 2017-04-14 Композиции и способы с использованием т-клеток с химерным рецептором аллоантигена RU2018140056A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662322937P 2016-04-15 2016-04-15
US62/322,937 2016-04-15
PCT/US2017/027754 WO2017181101A1 (en) 2016-04-15 2017-04-14 Compositions and methods of chimeric alloantigen receptor t cells

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RU2018140056A true RU2018140056A (ru) 2020-05-15
RU2018140056A3 RU2018140056A3 (enExample) 2020-10-16

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US (3) US20190153064A1 (enExample)
EP (1) EP3443076A4 (enExample)
JP (3) JP2019513394A (enExample)
KR (1) KR20190003550A (enExample)
CN (1) CN109328230A (enExample)
AU (2) AU2017248817A1 (enExample)
CA (1) CA3020599A1 (enExample)
MX (1) MX2018012539A (enExample)
RU (1) RU2018140056A (enExample)
WO (1) WO2017181101A1 (enExample)

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CN114369168B (zh) * 2020-10-19 2024-08-30 南京卡提医学科技有限公司 包含dap12和共刺激信号分子信号域的嵌合受体及其使用方法
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